Amyloidosis, Hereditary, Transthyretin-Related: all 82 studies
Page 1 of 1. Open to participants first (28), then studies with results posted, then the rest; newest registration first within each.
- Liver and Coagulation Disorders in Cardiac Transthyretin AmyloidosisRecruitingNCT07766135
- Cardiac Magnetic Resonance and Echocardiography Study With AcoramidisRecruitingNCT07695701Phase 4
- Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired SubpopulationsRecruitingNCT07654855
- Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament BiopsyRecruitingNCT07644325Not applicable
- ATTRACT-52: Primary Care Cardiac Amyloidosis Screening in Ordu, TurkeyEnrolling by invitationNCT07238426
- A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world SettingRecruitingNCT07235462
- The Eplontersen Pregnancy and Lactation Outcomes StudyRecruitingNCT07205666
- Phenotypic Manifestations of Hereditary ATTR AmyloidosisRecruitingNCT07124377
- To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)Not yet recruitingNCT07116473Phase 3
- Exercise in Hereditary ATTR (ATTRv) AmyloidosisRecruitingNCT07033715Not applicable
- Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)Not yet recruitingNCT06921408
- An Interventional Pilot Study to Investigate the Feasibility and Acceptance of a Structured Psychological Support Program for Patients, Caregivers, and Presymptomatic Carriers in Hereditary Transthyretin Amyloidosis With CardiomyopathyRecruitingNCT06907186Not applicable
- PL_GNT01_ISR_Grant 53234273Enrolling by invitationNCT06714019
- A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyEnrolling by invitationNCT06679946Phase 3
- Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR VariantRecruitingNCT06563895Phase 3
- A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)RecruitingNCT06539208Phase 1/2
- Non-interventional Study of Patients With Transthyretin (ATTR) AmyloidosisRecruitingNCT06465810
- New Biomarkers and Plasma Prothrombotic Potential in Cardiac Transthyretin AmyloidosisRecruitingNCT06345235
- Phenotyping and Characterization of wtATTR-CM (TRACE 1)RecruitingNCT06291805
- MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)RecruitingNCT06128629Phase 3
- Exploring Biomarkers in Hereditary Transthyretin AmyloidosisRecruitingNCT05929209Not applicable
- The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.RecruitingNCT05814380
- Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic AmyloidosisRecruitingNCT05758493Phase 2
- Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEFRecruitingNCT05577819Not applicable
- Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR CarriersRecruitingNCT05489549
- Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese PopulationRecruitingNCT05409833
- ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)RecruitingNCT04561518
- TEGSEDI Pregnancy Surveillance ProgramNot yet recruitingNCT04270058
- Evuzamitide in PET/CT to Measure Potential Therapeutic Response in ATTRCompletedNCT05635045Phase 2Results posted
- Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.CompletedNCT05560555Results posted
- A Study to Examine the Clinical Effectiveness of Tafamidis in Patients With Mixed Phenotype Hereditary Transthyretin AmyloidosisCompletedNCT05139680Results posted
- A Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Participants With hATTR-PNTerminatedNCT04306510Phase 4Results posted
- HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyActive, not recruitingNCT04153149Phase 3Results posted
- APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)CompletedNCT03997383Phase 3Results posted
- Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver TransplantCompletedNCT03862807Phase 3Results posted
- Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid CardiomyopathyCompletedNCT03860935Phase 3Results posted
- HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)CompletedNCT03759379Phase 3Results posted
- ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)CompletedNCT02319005Phase 3Results posted
- APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated AmyloidosisCompletedNCT01960348Phase 3Results posted
- Doxycycline and TUDCA in Patients With Transthyretin Amyloid CardiomyopathyCompletedNCT01855360Phase 1/2Results posted
- Transthyretin Amyloidosis Outcome Survey (THAOS)CompletedNCT00628745Results posted
- Validation of a Questionnaire for Quality of Life Assessment in Patients With Transthyretin Amyloidosis.WithdrawnNCT07080268
- A Phase 3 Study of NTLA-2001 in ATTRv-PNActive, not recruitingNCT06672237Phase 3
- Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in RussiaCompletedNCT06414746
- Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid CardiomyopathyCompletedNCT06393465
- hATTR Polyneuropathy in RussiaCompletedNCT06365593
- Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With PolyneuropathyActive, not recruitingNCT06360289
- Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in RussiaTerminatedNCT06338839
- Myocardial Effects in Patients With ATTRv With Polyneuropathy Treated With Patisiran or VutrisiranActive, not recruitingNCT05873868
- Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart TransplantationActive, not recruitingNCT05489523Phase 4
- Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR CardiomyopathyCompletedNCT05374564Phase 1
- Early Detection of Neuropathy in ATTRvCompletedNCT05311488
- A Study to Characterize the Biodistribution of 124I-Labeled AT-03 in Patients With Systemic AmyloidosisCompletedNCT05201911Phase 1
- Analysis of the Instestinal Microbiome of Patients With Transthyretin AmyloidosisStatus unknownNCT05196594
- Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis PatientsCompletedNCT05075798
- Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran TherapyCompletedNCT05023889Early Phase 1
- The Effect of Tafamidis on Transthyretin Stabilization, Safety, Tolerability and Efficacy in Transthyretin Amyloid Polyneuropathy PatientsStatus unknownNCT04963985Phase 4
- Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic StenosisCompletedNCT04899180Early Phase 1
- Efficacy and Safety of Acoramidis (AG10) in Subjects with Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)WithdrawnNCT04882735Phase 3
- Screening for Amyloidosis Before Aortic Valve Elective ReplacementActive, not recruitingNCT04869631
- A Non-interventional Cohort Safety Study of Patients With hATTR-PNActive, not recruitingNCT04850105
- Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release SurgeryTerminatedNCT04611204
- Evaluation of a Claims-based Algorithm for the Identification of Transthyretin-mediated Amyloidosis (ATTR) Amyloidosis in Medical RecordsWithdrawnNCT04569903Early Phase 1
- Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin AmyloidosisStatus unknownNCT04563286
- ATTR-Cardiomyopathy Stabilization Following Tafamidis TherapyStatus unknownNCT04513600
- Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid PolyneurophathyWithdrawnNCT04418024Phase 3
- Prevalence of wtATTR-CM After Carpal Tunnel Release SurgeryCompletedNCT04276220Not applicable
- A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A MutationCompletedNCT04201418
- Screening for Systemic Amyloidosis Via the Ligamentum FlavumCompletedNCT03923920
- Cardiac Amyloidosis Screening at Trigger Finger ReleaseCompletedNCT03886155
- Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)CompletedNCT03591757Early Phase 1
- Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological StudyCompletedNCT03588468Not applicable
- Monitoring of Early Disease Progression in Hereditary Transthyretin AmyloidosisCompletedNCT03431896
- Positron Emission Tomography / Magnetic Resonance Imaging in Aortic StenosisCompletedNCT03352089
- TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive SubjectsCompletedNCT03237494
- Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown AetiologyCompletedNCT03190577Not applicable
- Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)Approved for marketingNCT02939820
- A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy SubjectsCompletedNCT02797847Phase 1
- Carpal Tunnel Syndrome and Amyloid CardiomyopathyCompletedNCT02792790
- Biomarker for Transthyretin-Related Familial Amyloidotic Polyneuropathy (BioTRAP)WithdrawnNCT02713880
- Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR AmyloidosisCompletedNCT02016365Phase 2
- Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin AmyloidosisCompletedNCT01171859Phase 2