Alopecia universalis clinical trials
The registry lists 31 studies for Alopecia universalis across more than 10 countries. 6 are recruiting or about to start. 3 of them are mainly about Alopecia universalis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-20.
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Who runs them
Pfizer (5) · Aclaris Therapeutics, Inc. (3) · Equillium (2) · M.D. Anderson Cancer Center (2) · Erasmus Medical Center (2) · Yale University (2) · King Saud University (1) · Throne Biotechnologies Inc. (1)
What is being tested here
Drugs under test in Alopecia universalis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tofacitinib | 1 | 1 | 5 |
| PF-06651600 | 1 | 3 | 4 |
| Vancomycin | 1 | 0 | 1 |
| Neomycin | 1 | 0 | 1 |
| Methotrexate | 1 | 0 | 1 |
| Cyclosporine | 1 | 0 | 1 |
| Ifidancitinib | 0 | 0 | 3 |
| Dupilumab | 0 | 0 | 1 |
| Tralokinumab | 0 | 0 | 1 |
| Bexarotene | 0 | 1 | 1 |
Drug classes tested here JAK inhibitors 2 open · Tyrosine kinase inhibitors (TKIs) 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Jul 2027Clinical Application of Stem Cell Educator Therapy in Alopecia Areata · Throne Biotechnologies Inc.
- Nov 2027Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness Study · Erasmus Medical Center
Who these studies take
Of the 4 Alopecia universalis studies recruiting now, 2 (50%) set no upper age limit and 2 (50%) stop at 75 or younger. 3 (75%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (25%) | 1 (25%) |
| 18 | 3 (75%) | 3 (75%) |
| 30 | 3 (75%) | 3 (75%) |
| 40 | 3 (75%) | 3 (75%) |
| 50 | 3 (75%) | 3 (75%) |
| 65 | 3 (75%) | 3 (75%) |
| 75 | 3 (75%) | 3 (75%) |
| 85 | 2 (50%) | 2 (50%) |
Across all 31 studies, recruiting or not: 32% stop at 75 or younger and 19% at 65; 32% take children; 0% are for women only and 0% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia AreataRecruitingNCT06873945Phase 311 countries
- Evaluation of Microbiota Transplant Therapy in Patients With Alopecia AreataRecruitingNCT06747611Phase 21 country
- Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)Not yet recruitingNCT07406204Phase 4
- Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness StudyRecruitingNCT07381556Phase 41 country
- Pre-approval Single-patient Expanded Access for Ritlecitinib (PF-06651600)AvailableNCT05522556
- Systemic Treatments for Alopecia Areata RegistryRecruitingNCT062833161 country
- Clinical Application of Stem Cell Educator Therapy in Alopecia AreataActive, not recruitingNCT04011748Phase 21 country
- Long-Term PF-06651600 for the Treatment of Alopecia AreataCompletedNCT04006457Phase 317 countries
- Rhofanib® (Tofacitinib) Safety and Effectiveness EvaluationCompletedNCT071014711 country
- PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATATerminatedNCT04517864Phase 24 countries
- Study of EQ101 in Adult Subjects With Moderate to Severe Alopecia AreataCompletedNCT05589610Phase 22 countries
- The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech RepublicCompletedNCT050986001 country
- Efficacy of Oral Tofacitinib in Moderate to Severe Alopecia Areata, Totalis and Universalis at Tertiary Care Hospital, Karachi.CompletedNCT06278402Phase 31 country
- Phase 2 Trial of BNZ-1 in Patients With Moderate to Severe Alopecia AreataWithdrawnNCT03532958Phase 2
- Treatment of Alopecia Areata (AA) With Dupilumab in Patients With and Without Atopic Dermatitis (AD)CompletedNCT03359356Phase 21 country
- Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia AreataCompletedNCT03800979Phase 41 country
- Clinical Trial to Evaluate the Efficacy of Fecal Microbiota Transplantation in Patients With Alopecia AreataWithdrawnNCT04238091Phase 2
- PF-06651600 for the Treatment of Alopecia AreataCompletedNCT03732807Phase 2/318 countries
- A Study With Ruxolitinib Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)TerminatedNCT02553330Phase 21 country
- ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Universalis (AU) and Alopecia Totalis (AT)TerminatedNCT03759340Phase 21 country
- A Randomised Control Trial of Integrative Cognitive Behavioural Therapy for AlopeciaCompletedNCT04205214Not applicable1 country
- Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Universalis (AU) and Alopecia Totalis (AT)CompletedNCT03315689Phase 21 country
- A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia AreataCompletedNCT02684097Phase 21 country
- Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia AreataCompletedNCT03551821Phase 21 country
- Alopecia Areata RegistryActive, not recruitingNCT000695891 country
- Topical Tofacitinib for the Treatment of Alopecia Areata and Its VariantsCompletedNCT02812342Phase 21 country
- Tofacitinib for the Treatment of Alopecia Areata and Its VariantsCompletedNCT02312882Not applicable1 country
- Tofacitnib for the Treatment of Alopecia Areata and VariantsCompletedNCT02197455Phase 21 country
- Phase II Randomized Bilateral Comparison of Topical Targretin Gel 1% in Alopecia AreataCompletedNCT00063076Phase 2/31 country
- The Randomized Double-blind Placebo-controlled Trial of Intralesional Botulinum Toxin A Injection for Recalcitrant Alopecia Totalis and Alopecia UniversalisCompletedNCT00997815Phase 2/31 country
- Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia AreataCompletedNCT01167946Phase 41 country