Adenoviridae Infections: all 136 studies

Page 1 of 2. Open to participants first (34), then studies with results posted, then the rest; newest registration first within each.

• 25BT056: Basket Study of Viral Cytotoxic T LymphocytesNot yet recruitingNCT07873970Early Phase 1
• ELderly REspiratory VIral CohortNot yet recruitingNCT07813481
• YSCH-01 Via Nebulization in Pulmonary Metastasis of Advanced Solid Tumors and Non-small Cell Lung Cancer (NSCLC)RecruitingNCT07793500Early Phase 1
• YH02 Injection for Intra-tumor Injection Therapy in Advanced Solid Tumors With Unresponsive or Failure-Treated CasesRecruitingNCT07697937Phase 2
• A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal CancersRecruitingNCT07544589Phase 1
• Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent GlioblastomaRecruitingNCT07538128Early Phase 1
• A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCTRecruitingNCT07387367Phase 3
• Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT07358910
• Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC AloneRecruitingNCT07225972Phase 3
• Adaptive RCT of Corticosteroids for Severe Adenovirus Pneumonia in AdultsNot yet recruitingNCT07152600Phase 3
• TETRAVI Expanded Access ProgramAvailableNCT07104591
• R-MVST Cells for Treatment of Viral Infections in Children and Young AdultsRecruitingNCT06926894Phase 1
• Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised ImmunityRecruitingNCT06909110Phase 1/2
• Study of Viral Respiratory InfectionsNot yet recruitingNCT06764381
• Evaluating the Safety and Efficacy of BioTTT001 in Patients With Recurrent/Progressive High-grade Glioma.Enrolling by invitationNCT06763965Phase 1/2
• Clinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant GliomaRecruitingNCT06585527Phase 1
• Effectiveness of a Single Dose of Betamethasone in Children With Symptomatic Adenovirus InfectionRecruitingNCT06299813Phase 3
• Virus and Bronchial Epithelium in Children and the ElderlyRecruitingNCT06224062Not applicable
• A Clinical Study Evaluating the Safety and Efficacy of BioTTT001 in Patients With Malignant Solid TumorsEnrolling by invitationNCT06215846Phase 1
• Anti-viral T-cell Therapy by Gamma CaptureEnrolling by invitationNCT06027879Phase 1/2
• Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell TransplantationRecruitingNCT05664126Phase 2
• R-MVST Cells for Treatment of Viral InfectionsRecruitingNCT05183490Phase 1
• Adoptive T-cell Therapy for Resistant Viral Infections After Allogeneic HSCTNot yet recruitingNCT05075837Phase 1
• Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV InfectionsRecruitingNCT04832607Phase 3
• Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus InfectionsRecruitingNCT04722029Phase 1/2
• TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.RecruitingNCT04013802Phase 1
• Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy VolunteersRecruitingNCT03878121Phase 1
• Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCTRecruitingNCT03665675Early Phase 1
• Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus InfectionRecruitingNCT03266627Phase 2
• Third Party Viral Specific T-cells (VSTs)RecruitingNCT02532452Phase 2
• Donor-Derived Viral Specific T-cells (VSTs)RecruitingNCT02048332Phase 1/2
• A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System®RecruitingNCT02007356Phase 2
• Viral Infections in Healthy and Immunocompromised HostsRecruitingNCT01306084
• The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known ImmunocompromiseRecruitingNCT01011712
• Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral InfectionTerminatedNCT06999603Phase 2Results posted
• Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell TransplantTerminatedNCT05305040Phase 2/3Results posted
• Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell TransplantationTerminatedNCT05179057Phase 3Results posted
• Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell TransplantCompletedNCT04693637Phase 2/3Results posted
• Viral Specific T-Lymphocytes to Treat Adenovirus, CMV and EBVTerminatedNCT04364178Phase 1/2Results posted
• Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal CancerCompletedNCT03916510Phase 1Results posted
• Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck CancerCompletedNCT03754933Phase 1/2Results posted
• Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced CancerCompletedNCT03384316Phase 1Results posted
• The AdAPT Trial; Adenovirus After Allogeneic Pediatric TransplantationTerminatedNCT03339401Phase 2Results posted
• Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant GliomaCompletedNCT03072134Phase 1Results posted
• Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate CancerCompletedNCT02555397Phase 1Results posted
• Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell TransplantCompletedNCT02108522Not applicableResults posted
• Study to Assess the Safety and Efficacy of Brincidofovir in Treatment of Early Versus Late Adenovirus InfectionCompletedNCT02087306Phase 3Results posted
• ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK VirusCompletedNCT01570283Phase 1/2Results posted
• Collection and Testing of Respiratory SamplesCompletedNCT01302418Results posted
• Study to Assess Brincidofovir Treatment of Serious Diseases or Conditions Caused by Double-stranded DNA VirusesCompletedNCT01143181Phase 3Results posted
• Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With MenTerminatedNCT00865566Phase 2Results posted
• NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1CompletedNCT00392015Phase 1/2Results posted
• A Clinical Trial to Evaluate the Safety, Efficacy, and Immunogenicity of DR-5001CompletedNCT00382408Phase 3Results posted
• LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in AustraliaStatus unknownNCT06392451Not applicable
• Comparison of Nasopharyngeal Swab v. Nasopharyngeal Saline Wash or Saliva Collection in Testing for Respiratory VirusesActive, not recruitingNCT05864118Not applicable
• T Lymphocytes for the Treatment of AdV, CMV, EBV, BKV and Aspergillus Fumigatus Infections After Allogeneic Stem Cell TransplantationCompletedNCT05471661Phase 1/2
• Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.Active, not recruitingNCT05271318Phase 1/2
• Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer PatientsTerminatedNCT05101213Phase 1
• Phase 1 Trial of ChAd68 and Ad5 Adenovirus COVID-19 Vaccines Delivered by AerosolCompletedNCT05094609Phase 1
• An Exploratory Trial to Evaluate Efficacy and Safety for Combination Treatment of Adenovirus Double Suicide Gene TherapyStatus unknownNCT04739046Phase 2
• A Phase 2a Study of IV BCV in Subjects With Adenovirus InfectionCompletedNCT04706923Phase 2
• TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 MonotherapyCompletedNCT04695327Phase 1
• A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid TumorsActive, not recruitingNCT04673942Phase 2
• A Study to Test Three Experimental HIV Vaccines in Healthy Adults.Status unknownNCT04553016Phase 1
• Adenovirus Keratoconjunctivitis and OphtalmologyStatus unknownNCT04417244
• A Clinical Trial of AdNRGM Plus CB1954 in Prostate CancerCompletedNCT04374240Phase 1
• Corneal Densitometry Changes With Adenoviral SEICompletedNCT04267991
• First in Man Clinical Study to Evaluate Safety and Tolerability of an Oncolytic Adenovirus in Prostate Cancer Patients.Active, not recruitingNCT04097002Phase 1/2
• Interest of Rapid Typing in Adenovirus Infections.CompletedNCT04056546
• Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus ViremiaWithdrawnNCT03532035Phase 2
• Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell TransplantationActive, not recruitingNCT03475212Phase 1/2
• Effect of Adenovirus E1A Oncogene on DNA Replication DynamicsStatus unknownNCT03325517
• Non Randomized Comparative Study With ControlStatus unknownNCT03294824
• Evaluate Efficacy, Immunological Response of Intratumoral/Intralesional Oncolytic Virus (OBP-301) in Metastatic MelanomaStatus unknownNCT03190824Phase 2
• A Study to Assess the Safety, Pharmacodynamics, and Immunogenicity of PXVX0047TerminatedNCT03160339Phase 1
• Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic InfectionsTerminatedNCT03159364Phase 1/2
• Oncolytic Adenovirus-Mediated Gene Therapy for Lung CancerWithdrawnNCT03029871Phase 1
• Specific Respiratory Infections as Triggers of Acute Medical EventsCompletedNCT02984280
• Clinical Trial Phase I for Theragene in Combination With Chemotherapy for the Locally Advanced Pancreatic CancerCompletedNCT02894944Phase 1
• Clinical Grade Adenovirus Specific T Cells for Immunotherapy After Allogeneic Stem Cell Transplantation (CTL-ADV)CompletedNCT02851576Phase 1/2
• A Multicenter Randomized Double-blind Placebo-controlled Pilot Study of Safety, Pharmacodynamics and Efficacy of Different Treatments of Immunotherapeutic Drug Mobilan (M-VM3) in Patients With Diagnosed Prostate CancerStatus unknownNCT02844699Phase 1/2
• Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ TransplantationStatus unknownNCT02779439Phase 1
• LOAd703 Oncolytic Virus Therapy for Pancreatic CancerCompletedNCT02705196Phase 1/2
• Virus-specific ImmunoTherapy Following Allogeneic Stem Cell TransplantationWithdrawnNCT02702427Phase 1/2
• Safety and Tolerability Clinical Trial of Different Doses of the Immunotherapeutic Drug Mobilan (M-VM3) and Placebo in Patients With Prostate CancerCompletedNCT02654938Phase 1
• Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or DiseaseNo longer availableNCT02596997
• A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304TerminatedNCT02420080
• Phase 1 Clinical Trial of the Safety and Immunogenicity of an Adenovirus-based TB Vaccine Administered by AerosolCompletedNCT02337270Phase 1
• Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)WithdrawnNCT02276820Phase 1
• Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral InfectionsTerminatedNCT02231853Phase 1
• Safety and Efficacy of CG0070 Oncolytic Virus Regimen in Patients With High Grade Non-Muscle Invasive Bladder CancerWithdrawnNCT02143804Phase 2
• Residual Sample Collection for Respiratory Viral PanelCompletedNCT02049918
• Ad Sensor-based Real-time Diagnosis of AdenovirusStatus unknownNCT02008812Not applicable
• Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)CompletedNCT01945814Phase 1
• Allogeneic Virus-Specific Cytotoxic T-Lymphocytes(CTL), Persistent/Recurrent Viral Infection Post-HSCT (EAP CHALLAH)No longer availableNCT01945619
• Safety Study of Adenovirus Hepatocyte Growth Factor to Treat Ischemic Heart DiseaseStatus unknownNCT01925352Phase 1/2
• Cytotoxic T Cells to Prevent Virus InfectionsCompletedNCT01923766Phase 1
• Phase I Endovenous Administration of Oncolytic Adenovirus ICOVIR-5 in Patients With Advanced or Metastatic MelanomaCompletedNCT01864759Phase 1
• Study of a Novel Therapeutic Vaccine Against Hepatitis C Using Ad6NSmut and MVA-NSmut in Chronically Infected PatientsCompletedNCT01701336Phase 1
• Evaluate the Use of Ganciclovir Gel 0.3% for the Treatment of Conjunctivitis Caused by AdenovirusStatus unknownNCT01600365Phase 3

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