An observational study in Exercise Training, sponsored by Poznan University of Physical Education. Not yet recruiting. Open to male participants aged 14 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Poznan University of Physical Education · Observational
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Among 13 studies in Motor Activity by Poznan University of Physical Education — 6 open to participants now, 7 under way, none of them phase 3. Motor Activity · Poznan University of Physical Education.
Among the 13 studies in Motor Activity by Poznan University of Physical Education, this one is one of 4 that started in 2026, is one of 2 observational ones, and was the 13th registered.
9,809 studies on the registry are indexed under Motor Activity; 1,915 are open to participants now.
Browse Motor Activity studies →6 of the 13 studies in Motor Activity by Poznan University of Physical Education are open now, in 1 country. Recruiting first, the newest first:
Poznan University of Physical Education · Sites in Poland
Ages 14–19 · Women only · Healthy volunteers
Poznan University of Physical Education · Sites in Poland
Ages 50+ · Healthy volunteers
Poznan University of Physical Education · Sites in Poland
Ages 50+ · Women only · Healthy volunteers
Poznan University of Physical Education · Sites in Poland
Ages 16–22 · Women only · Healthy volunteers
Poznan University of Physical Education
Ages 35–75 · Women only · Healthy volunteers
By country, each count listing its studies:
Of the 1,203 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 538 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 14 Years to 35 Years · male · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
13 studies; the count open now beside each. This study's row is marked.
First in 2014; this study’s year is marked. 4 started in 2026.
This study's planned enrollment of 45 is below the median of 98 across 1,237 observational studies indexed under Motor Activity.
Median enrollment 100 across the 11 interventional studies, 29 across the 2 observational. Of the 6 that completed or were terminated, 0 (0%) have results posted.
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Poznan University of Physical Education is the lead sponsor of 91 studies on the registry; 28 are open to participants now.
6 of the studies in Motor Activity by Poznan University of Physical Education that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07933770Poznan University of Physical EducationAge-Related Differences in Exercise-Induced Immune Responses in Soccer Players | 2026-11-30 |
| NCT07752459Poznan University of Physical EducationPhysiological Responses to Basketball-Specific Interval Exercise in Female Basketball Players | 2026-11-30 |
| NCT06606769Poznan University of Physical EducationPhysical Activity Guarantees Bone Density. | 2026-12-31 |
| NCT06682741Poznan University of Physical EducationComparison of Different Training Programs on Cognitive Function | 2026-12-31 |
| NCT06606678Poznan University of Physical EducationThe Role of Regular Physical Activity in Enhancing Metabolic Health, Reducing Inflammation, and Improving Gut Function | 2026-12-31 |
Add all 6 to your calendar (.ics) → With an account.
Among the 13 studies in Motor Activity by Poznan University of Physical Education, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study aims to investigate age-related differences in exercise-induced innate immune responses in adolescent and adult soccer players. Participants will be divided into three age groups: 14-15 years, 16-17 years, and 18 years and older.
All participants will perform a maximal 20-meter shuttle run test (Beep Test). Blood samples will be collected at three time points: before exercise (PRE), immediately after exercise (POST), and 60 minutes after exercise (REC).
The study will assess changes in circulating biomarkers associated with intestinal barrier function and innate immune activation, including lipopolysaccharide (LPS), lipopolysaccharide-binding protein (LBP), soluble CD14 (sCD14), and soluble Toll-like receptors. Additionally, TLR2 and TLR4 expression on peripheral blood leukocytes will be evaluated using flow cytometry, and TLR2 and TLR4 gene expression will be assessed in peripheral blood mononuclear cells.
The primary objective is to determine whether acute exercise-induced immune responses and subsequent recovery differ between age groups. The findings may provide insight into age-related variations in physiological responses to high-intensity exercise in soccer players.
The study population will consist of trained male soccer players aged 14 years and older who regularly participate in organized soccer training. Participants will be divided into three age groups: 14-15 years, 16-17 years, and 18 years and older. All participants will undergo a maximal 20-meter shuttle run test (Beep Test) to assess exercise-induced changes in hematological parameters, intestinal barrier biomarkers, and innate immune responses. Venous blood samples will be collected before exercise, immediately after exercise, and 60 minutes after exercise. The study will compare the magnitude and recovery patterns of physiological and immunological responses across the three age groups.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Autoimmune disease
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Aged 14-15 Years
Other: Beep test
16-17 Years
Other: Beep test
18 Years and Older
Other: Beep test
Trained adult soccer players aged 18 years and older. Participants will perform a maximal 20-meter shuttle run test (Beep Test). Blood samples will be collected before exercise (PRE), immediately after exercise (POST), and 60 minutes after exercise (REC) to assess exercise-induced changes in intestinal barrier biomarkers and innate immune responses, including TLR2 and TLR4 expression.
Exercise-Induced Change in Circulating Lipopolysaccharide (LPS) Concentration
Circulating lipopolysaccharide (LPS) concentration will be measured using an ELISA assay in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in circulating LPS concentrations and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in Circulating Lipopolysaccharide binding protein (LBP) Concentration
Circulating lipopolysaccharide binding protein (LBP) concentration will be measured using an ELISA assay in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in circulating LPS concentrations and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in Circulating Soluble CD14 (sCD14) Concentration
Circulating Soluble CD14 (sCD14) concentration will be measured using an ELISA assay in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in circulating LPS concentrations and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in Circulating Soluble Toll-Like Receptor 4 (sTLR4) Concentration
Circulating Soluble Toll-Like Receptor 4 (sTLR4) concentration will be measured using an ELISA assay in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in circulating LPS concentrations and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in Circulating Soluble Toll-Like Receptor 2 (sTLR2) Concentration
Circulating Soluble Toll-Like Receptor 2 (sTLR2) concentration will be measured using an ELISA assay in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in circulating LPS concentrations and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in CD14+ Monocyte Population
The proportion of CD14+ monocytes will be assessed by flow cytometry in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in the CD14+ monocyte population and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in CD16+ Monocyte Population
The proportion of CD16+ monocytes will be assessed by flow cytometry in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in the CD14+ monocyte population and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in TLR2 Monocyte Population
The proportion of TLR2 monocytes will be assessed by flow cytometry in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in the CD14+ monocyte population and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in TLR4 Monocyte Population
The proportion of TLR2 monocytes will be assessed by flow cytometry in blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in the CD14+ monocyte population and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in TLR2 Gene Expression in Peripheral Blood Mononuclear Cells
TLR2 gene expression will be assessed in peripheral blood mononuclear cells (PBMCs) isolated from blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). TLR2 gene expression will be quantified using real-time quantitative PCR (RT-qPCR) and normalized to the reference gene GUSB. The outcome will be used to assess exercise-induced changes in TLR2 gene expression and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Change in TLR2 Gene Expression in Peripheral Blood Mononuclear Cells
TLR4 gene expression will be assessed in peripheral blood mononuclear cells (PBMCs) isolated from blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). TLR2 gene expression will be quantified using real-time quantitative PCR (RT-qPCR) and normalized to the reference gene GUSB. The outcome will be used to assess exercise-induced changes in TLR4 gene expression and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Exercise-Induced Changes in Complete Blood Count Parameters
Complete blood count parameters, including hemoglobin, hematocrit, erythrocyte count, leukocyte count, granulocyte count, lymphocyte count, monocyte count, platelet count, MCV, MCH, MCHC, and RDW, will be assessed in venous blood samples collected before exercise (PRE), immediately after exercise (POST), and 1 hour after exercise (REC). Measurements will be performed during a single study session involving a maximal 20-meter shuttle run test (Beep Test). The outcome will be used to assess exercise-induced changes in hematological parameters and to determine whether these responses differ among three age groups of soccer players: 14-15 years, 16-17 years, and 18 years and older.
Time frame: Baseline (before exercise, immediately after exercise, and 1 hour after exercise).
Body Mass
Body mass will be measured before the exercise test. Body mass will be reported in kilograms (kg).
Time frame: Baseline - in the morning
Dietary Intake Assessed Using a Food Diary
Dietary intake will be assessed using a food diary completed on the day preceding each exercise test. Total energy intake and macronutrient intake, including protein, carbohydrate, and fat, will be calculated from the dietary records.
Time frame: The day before exercise test.
Body Fat Percentage
Body fat percentage will be measured before the exercise test. Body fat will be reported in percentage (%).
Time frame: Baseline - in the morning
Fat-Free Mass
Fat-Free Mass will be measured before the exercise test. Fat-Free Mass be reported in percentage (%).
Time frame: Baseline - in the morning
Total body water
Total body water will be assessed before the exercise test at baseline. Total body water will be reported in percentage (%).
Time frame: Baseline - in the morning
Height
Height will be assessed before the exercise test at baseline. Height will be reported in centimeters \[cm\].
Time frame: Baseline - in the morning
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Nov 2026; primary completion for Nov 2026, 0 months later.
Of 490 non-industry observational studies under Motor Activity, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 48. This study's planned 0 months is below that.
Counting every sponsor, half of 500 studies reached it within 22 months; a quarter within 8 and three quarters within 48.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Poznan University of Physical Education