An interventional study of Tailored exercise program in Cognition, Postoperative Delirium and Preoperative Aerobic Training, sponsored by Stanford University. Not yet recruiting at 1 site in United States. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-11-12.
Sponsored by Stanford University · Not applicable, Interventional, and Prevention
Among 81 studies in Emergence Delirium with a site in United States — 19 open to participants now, 20 under way, 2 of them phase 3. Emergence Delirium · United States.
Among the 81 studies in Emergence Delirium with a site in United States, this one is the 58th largest by planned enrollment of the 65 interventional ones that give a count, is one of 2 that started in 2027, is one of 30 with no phase, reaches primary completion later than 7 of the 19 other live ones, and was the 81st registered.
751 studies on the registry are indexed under Emergence Delirium; 262 are open to participants now.
Browse Emergence Delirium studies →19 of the 81 studies in Emergence Delirium with a site in United States are open now. Recruiting first, the newest first:
University of Pittsburgh · Sites in United States
Ages 65+
Boston Children's Hospital · Sites in United States
Ages 1–12
The Methodist Hospital Research Institute · Sites in United States
Ages up to 65
Northwestern University · Sites in United States
Ages 18+
University of Chicago · Sites in United States
Ages 18+
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 143 Emergence Delirium studies recruiting now, 78 (55%) set no upper age limit and 45 (31%) stop at 75 or younger; 35 take children under 18; 25 take healthy volunteers.
This study: 50 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
81 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 4 · Phase 2 11 · Phase 3 10 · Phase 4 13
First in 2002; this study’s year is marked. 2 started in 2027.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 15 is below the median of 120 across 464 interventional studies indexed under Emergence Delirium.
Median enrollment 100 across the 65 interventional studies, 217 across the 16 observational. Of the 59 that completed or were terminated, 33 (56%) have results posted.
This tab as a report to print or save as PDF → With an account.
1 of 81 have an industry lead sponsor. The 10 most frequent:
Stanford University is the lead sponsor of 2,170 studies on the registry; 433 are open to participants now.
Of its 267 completed or terminated interventional studies of FDA-regulated products, 207 (78%) have results posted.
Stanford University has 6 studies filed under Emergence Delirium — fewer than ten, so there is no comparison to draw.
9 of the studies in Emergence Delirium with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06133842Beth Israel Deaconess Medical CenterCEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State | 2026-12 |
| NCT06324955Boston Children's HospitalLanguage During Inhalational Induction | 2027-03 |
| NCT06036095Oregon Health and Science UniversityTotal Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study | 2027-03-15 |
| NCT07933003Stanford UniversityPrehab-COG: Does Preoperative Exercise Improve Postoperative Cognitive Outcomes? | 2027-06 |
| NCT07672301University of ChicagoTotal Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty | 2027-06 |
Add all 9 to your calendar (.ics) → With an account.
Among the 81 studies in Emergence Delirium with a site in United States, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The purpose of this protocol is to evaluate the feasibility and acceptability of a preoperative exercise intervention (Prehabilitation) program, along with intraoperative Electroencephalography (EEG) recordings, and pre and post operative cognitive testing in older patients undergoing a major surgery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The participants will undergo the virtual exercise intervention 2xweek for 3-4 weeks prior to surgery, and take cognitive testing with non-invasive EEG recordings at 5-point time (the baseline prior to start of the exercise program, at 2-4 days prior to surgery, during the surgery, post-op, and 30-day post surgery). Participants will also be interviewed after the intervention and after surgery to obtain their feedback on their experience with the study procedures.
Behavioral: Tailored exercise program
Eligible participants will receive their exercise program, relevant informational material and training. The exercise program will be tailored to the physical fitness of the participants. The 2xweek virtual sessions take 30 minutes each and include guided exercises at mild-moderate intensity.
Evaluate the feasibility of a preoperative home-based exercise intervention program, with intraoperative EEG recording, and pre and post operative cognitive testing, among older patients undergoing major surgery.
Feasibility will be measured by: 1. Proportion of Eligible Patients Approached Who Enrolled (Number of eligible patients who enrolled divided by the number of eligible patients approached) 2. Proportion of Enrolled Participants Completing All Planned Study Data-Collection Assessments (Number and the percentage of the completion for each of the planned data collection points)
Time frame: Maximum 3 months from participant enrollment to end/completion of all study-related tasks.
Evaluate the acceptability of a preoperative home-based exercise intervention program, with intraoperative EEG recording, and pre and post operative cognitive testing, among older patients undergoing major surgery.
Acceptability will be measured by: 1\) Aggregated (mean) Score of Surveyed Participants' Rating Across Each Study-Task (Average score of participants' ratings across study tasks, including exercise program, EEG recording and cognitive testing).
Time frame: Maximum 3 months from participant enrollment to end/completion of all study-related tasks.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Jan 2027; primary completion for Jun 2027, 5 months later.
Of 184 non-industry interventional studies with no phase under Emergence Delirium, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's planned 5 months is below that.
Counting every sponsor, half of 184 studies reached it within 19 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.