An interventional study of Culturally-Tailored AI Chatbot Simulation and Instructor-Facilitated Peer Role-Play in Therapeutic Communication, sponsored by Alexandria University. Not yet recruiting at 1 site in Egypt. Per ClinicalTrials.gov, last updated 2026-10-29.
Sponsored by Alexandria University · Not applicable, Interventional, and Other
Therapeutic communication and empathy are core competencies in psychiatric nursing, yet students often have limited opportunities to practise them safely with culturally realistic patients and families. This randomized controlled trial will test whether a culturally tailored, large language model (LLM)-driven AI chatbot simulation improves therapeutic communication competence and empathy among fourth-year nursing students at the Faculty of Nursing, Alexandria University, Egypt.
Alexandria University is the lead sponsor of 596 studies on the registry; 134 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
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Exclusion Criteria:
Participants continue the standard psychiatric nursing curriculum and additionally complete the orientation and three AI-simulated cases individually on the platform, one module per week.
Behavioral: Culturally-Tailored AI Chatbot Simulation
Participants continue the standard psychiatric nursing curriculum and additionally complete instructor-facilitated peer role-play of the same orientation and three cases, matched in number, order, and length to the intervention arm.
Other: Instructor-Facilitated Peer Role-Play
Four weekly individual modules on a secure web-based platform: a 20-minute orientation and three 15-20-minute cases (major depressive disorder, schizophrenia spectrum disorder, bipolar I disorder, manic episode). Students hold free-text conversations with an LLM-driven simulated patient and family member in culturally embedded scenarios (Egyptian colloquial Arabic, idioms of distress, religious explanatory models, family reputation and stigma, medication cost) with bracketed non-verbal cues. Platform features include a Perspective-Taking Drill ("If I were the patient right now, I would feel...") and automated feedback with separate communication and empathy scores. Students follow the Student Clinical Handout, which includes a safety and crisis escalation protocol. Modules are ungraded and an instructor is available in every session.
Instructor-facilitated role-play in pairs of the same orientation and three cases, matched to the intervention arm in number, order, and length of sessions, using the same Student Clinical Handout. Partners alternate nurse and patient roles using script cards with the same case, cultural content, and cue descriptions; an additional student plays the family member. No AI-embedded Perspective-Taking Drill or automated feedback is provided.
Kiersma-Chen Empathy Scale-Revised (KCES-R)
Time frame: Baseline (one week before the intervention) and immediately after the final simulation module (week 4)
Observer-rated therapeutic communication competence (behavioral checklist total score)
Time frame: Baseline (one week before the intervention) and immediately after the final simulation module (week 4)
Retention of empathy ability: KCES-R Personal Empathy Ability score at four-week follow-up
Time frame: Baseline, immediately after the final module (week 4), and four weeks after the final module
Start is estimated for Oct 2026; primary completion for Dec 2026, 2 months later.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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