An interventional study of Computer-Controlled Local Anesthetic Delivery System (CALAJECT) and Conventional Inferior Alveolar Nerve Block Injection in Local Anesthesia in Dentistry, sponsored by Inonu University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-10-28.
Sponsored by Inonu University · Not applicable, Interventional, and Other
This randomized controlled clinical trial aims to compare the effects of a computer-controlled local anesthetic delivery system (CALAJECT) and the conventional injection technique for inferior alveolar nerve block (IANB) on injection pain, heart rate, and blood pressure in adult patients. Participants requiring dental treatment of mandibular posterior teeth will be randomly assigned to receive IANB using either the CALAJECT system or the conventional injection technique. Pain experienced during the anesthetic injection will be evaluated using a Visual Analog Scale (VAS). Heart rate and blood pressure will be recorded before and after the injection to evaluate cardiovascular responses. The study aims to determine whether the method of local anesthetic administration influences patient-reported pain and cardiovascular responses during IANB.
Inonu University is the lead sponsor of 391 studies on the registry; 93 are open to participants now.
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Participants assigned to this group will receive an inferior alveolar nerve block using the CALAJECT computer-controlled local anesthetic delivery system.
Device: Computer-Controlled Local Anesthetic Delivery System (CALAJECT)
Participants assigned to this group will receive an inferior alveolar nerve block using the conventional injection technique.
Procedure: Conventional Inferior Alveolar Nerve Block Injection
Inferior alveolar nerve block anesthesia will be administered using the CALAJECT computer-controlled local anesthetic delivery system.
Conventional inferior alveolar nerve block anesthesia will be administered using a standard manual dental syringe.
Pain Perception During Inferior Alveolar Nerve Block Injection
Pain associated with the inferior alveolar nerve block injection will be assessed using the Heft-Parker Visual Analog Scale (VAS). Participants will indicate their perceived pain intensity on the scale, with higher scores indicating greater pain intensity. Pain scores will be compared between the CALAJECT and conventional injection groups.
Time frame: immediately after completion of the local anesthetic injection
Change in Heart Rate Associated With Local Anesthetic Injection
Heart rate will be measured using a finger pulse oximeter placed on the left index finger. Heart rate will be recorded every 30 seconds for 2 minutes before the injection and every 30 seconds for 2 minutes immediately after completion of the injection. The mean heart rate for each 2-minute period will be calculated and compared between the CALAJECT and conventional injection groups.
Time frame: From 2 minutes before injection to 2 minutes after completion of injection
Change in Blood Pressure Associated With Local Anesthetic Injection
Systolic and diastolic blood pressure will be measured using a digital blood pressure monitor on the left arm before and after the local anesthetic injection. Changes in blood pressure will be compared between the CALAJECT and conventional injection groups.
Time frame: Before and immediately after completion of the local anesthetic injection
Plan to share: No
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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