An interventional study of Aerobic Exercise and Anaerobic Exercise in Exercise Physiology and Metabolic Hormones, sponsored by Inonu University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-04.
Sponsored by Inonu University · Not applicable, Interventional, and Basic science
This interventional study aims to investigate the acute effects of three different exercise modalities-aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT)-on irisin, leptin, and ghrelin levels in sedentary women. A total of 20 sedentary women will participate in the study. Hormonal responses will be evaluated in relation to the exercise sessions to determine exercise-induced changes in irisin, leptin, and ghrelin and to compare the responses associated with the three exercise modalities.
This interventional study is designed to investigate and compare the acute effects of aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT) on irisin, leptin, and ghrelin levels in sedentary women. A total of 20 sedentary women will participate in the study.
Participants will complete three different exercise conditions: aerobic exercise, anaerobic exercise, and HIIT. Irisin, leptin, and ghrelin levels will be evaluated in relation to each exercise condition to determine acute exercise-induced hormonal responses. The study will compare changes in these biomarkers across the three exercise modalities to determine whether the hormonal responses differ according to exercise type.
The study is intended to provide a better understanding of the acute endocrine and metabolic responses to exercise modalities with different physiological demands in sedentary women, with particular emphasis on irisin, leptin, and ghrelin.
Inclusion Criteria: Female participants Sedentary individuals Voluntary participation in the study Ability and willingness to complete the planned exercise sessions
Exclusion Criteria: Inability to participate in the planned exercise sessions Withdrawal of consent or unwillingness to continue participation
Participants in this arm will complete three different exercise conditions in separate sessions: aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT). Irisin, leptin, and ghrelin levels will be assessed in relation to each exercise condition to evaluate and compare acute hormonal responses across the three exercise modalities.
Behavioral: Aerobic Exercise · Behavioral: Anaerobic Exercise · Behavioral: High-Intensity Interval Training (HIIT)
Participants will complete an aerobic exercise session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to aerobic exercise.
Participants will complete an anaerobic exercise session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to anaerobic exercise.
Participants will complete a high-intensity interval training (HIIT) session as one of the three exercise conditions. Irisin, leptin, and ghrelin levels will be assessed in relation to the exercise session to determine the acute hormonal response to HIIT.
Change in Irisin Level
Irisin levels will be assessed in relation to each exercise condition to determine the change in circulating irisin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT)
Time frame: Pre-exercise and immediately post-exercise during each exercise session
Change in Leptin Level
Leptin levels will be assessed in relation to each exercise condition to determine the change in circulating leptin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT).
Time frame: Pre-exercise and immediately post-exercise during each exercise session
Change in Ghrelin Level
Ghrelin levels will be assessed in relation to each exercise condition to determine the change in circulating ghrelin levels associated with aerobic exercise, anaerobic exercise, and high-intensity interval training (HIIT).
Time frame: Pre-exercise and immediately post-exercise during each exercise session
Plan to share: No — There is no plan to make individual participant data (IPD) available to other researchers.
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Inonu University