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CompletedNCT07898735Updated Oct 27, 2026

Applying of Absorbable Dressing (Reso-Pac) on the Palatal Donor Site

An interventional study of Control group : Coe-pak and Study Group: Reso-pac in Keratinized Tissue Deficiency, sponsored by Damascus University. Completed at 1 site in Syria. Open to participants aged 18 Years to 30 Years. Per ClinicalTrials.gov, last updated 2026-10-27.

Sponsored by Damascus University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 3 years 6 months after the study started (first participant enrolled Mar 2023, registered Sep 2026).
Updated Oct 27, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
01

Study summary

The periodontal dressing was applied to the donor site of the free gingival graft on the palate to protect the site, reduce postoperative pain, and improve soft tissue healing in the palatal area.

Read the detailed description

Traditional periodontal dressings require mechanical retention within the interdental spaces and lack bioactive agents that promote healing or reduce pain.

In contrast, the adhesive dressing used in the study group adheres to soft tissues and contains bioactive agents that help reduce pain and enhance healing.

02

Conditions studied

  • Keratinized Tissue Deficiency

Keywords

  • Free Gingival graft
  • Donor Site
  • Periodental Dressing
  • Mucogingival Surgery
03

In context

Lead sponsor

Damascus University is the lead sponsor of 212 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Width of attached gingiva less than 2 mm.

    • Patient age between 18 and 30 years.
    • Good oral hygiene (Plaque Index \< 1).
    • Absence of periodontal inflammation in the area and no surgical procedures performed there within the preceding six months.

Exclusion criteria

Exclusion Criteria:

  • Systemic diseases preventing surgery.
  • Diseases and medications affecting healing.
  • Cellulose allergy.
  • Smokers.
  • Pregnant and breastfeeding women.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
20 participants (actual)

Study arms

  • Other
    Control group : Coe-Pak

    \- Control group (Coe-Pack): : Coe-Pak periodontal dressing applied to the palatal donor site immediately after free gingival graft harvesting and maintained for one week.

    Other: Control group : Coe-pak

  • Other
    Study group : Reso-pac

    \- Study group (Reso-Pac):Reso-Pac resorbable periodontal dressing applied to the palatal donor site immediately after free gingival graft harvesting and maintained for one week.

    Other: Study Group: Reso-pac

Interventions

  • OtherControl group : Coe-pak

    \- Control group (Coe-Pack): Coe-Pack dressing is applied to the palatal donor site after harvesting the epithelial graft.

  • OtherStudy Group: Reso-pac

    \- Study group (Reso-Pac): Reso-Pac dressing is applied to the palatal donor site after harvesting the epithelial graft.

06

What researchers measure

Primary outcomes

  1. Outcome MeasuresTitle: Pain Index

    The Visual Analog Scale (VAS) was used to assess patients' pain and discomfort daily for one week following treatment. The patient was given a sheet containing a pain scale on which to record their pain level daily. This scale was divided into 100-millimeter increments; a score of 0 at the left end of the scale indicated no pain, while a score of 100 at the right end indicated unbearable pain.

    Time frame: Time frame :T1: Day 1 post-surgery , T2 : Day 2 Post-surgery , T3: Day 3 post-surgery , T4: Day 4 post-surgery , T5: Day 5 post-surgery , T6: Day 6 post-surgery, Time Final: Day 7 post-surgery..

07

Study locations

1 site
  • Department of Periodontology - Faculty of Dentistry - Damascus University
    Damascus, Syria
08

References and documents

Publications

  • Paljevic E, Brekalo Prso I, Hrstic JV, Pezelj-Ribaric S, Persic Bukmir R. Impact of Smoking on the Healing of Apical Periodontitis after Nonsurgical Endodontic Treatment. Eur J Dent. 2024 Feb;18(1):124-130. doi: 10.1055/s-0043-1761451. Epub 2023 Mar 28. PubMed 36977477 ↗
  • Khalil S, Habashneh RA, Alomari S, Alzoubi M. Local application of hyaluronic acid in conjunction with free gingival graft: a randomized clinical trial. Clin Oral Investig. 2022 Feb;26(2):2165-2174. doi: 10.1007/s00784-021-04197-9. Epub 2021 Oct 8. PubMed 34623507 ↗
  • Raghavan SL, Panneerselvam E, Mudigonda SK, Raja KKVB. Protection of an intraoral surgical wound with a new dressing: a randomised controlled clinical trial. Br J Oral Maxillofac Surg. 2020 Sep;58(7):766-770. doi: 10.1016/j.bjoms.2020.03.017. Epub 2020 Apr 9. PubMed 32279888 ↗
  • Bahammam S, Chen CY, Ishida Y, Hayashi A, Ikeda Y, Ishii H, Kim DM, Nagai S. Electric and Manual Oral Hygiene Routines Affect Plaque Index Score Differently. Int J Environ Res Public Health. 2021 Dec 12;18(24):13123. doi: 10.3390/ijerph182413123. PubMed 34948732 ↗

Individual participant data

Plan to share: No

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 27, 2026
Show all 1 update
  1. Oct 27, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07898735
Responsible party
Sponsor
First posted
Oct 27, 2026
Start date
Mar 22, 2023
Primary completion
Apr 28, 2024
Completion
May 27, 2024
Last update
Oct 27, 2026

Study contacts

MohamadMonzer AlSabbagh, DDS MSc PhD
principal investigator · Department of Periodontology - Faculty of Dentistry - Damascus University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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