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RecruitingNCT07890181Updated Oct 22, 2026

Geographic Mismatch as A Predictor of Short-Term Major Adverse Cardiovascular Events Following Long Coronary Stent Implantation

An observational study in Geographic Mismatch, Short-Term and Major Adverse Cardiovascular Events, sponsored by Sohag University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Sohag University · Observational

From the registry’s dates

  • Started Sep 2026; still recruiting 1 month later.
Updated Oct 22, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
650
Ages
18 Years and older
Sex
All
01

Study summary

This study aims to evaluate whether geographic mismatch is an independent predictor of short-term major adverse cardiovascular events following long coronary stent implantation.

Read the detailed description

Coronary artery disease (CAD) remains one of the leading causes of morbidity and mortality worldwide despite substantial advances in preventive strategies, pharmacological therapy, and coronary revascularization techniques.

Percutaneous coronary intervention (PCI) has become the standard treatment for many patients with obstructive CAD and has significantly improved both short- and long-term clinical outcomes.

Several clinical, angiographic, and procedural factors have been identified as predictors of adverse outcomes following PCI, including advanced age, diabetes mellitus, chronic kidney disease, left ventricular dysfunction, lesion complexity, and total stent length.

02

Conditions studied

  • Geographic Mismatch
  • Short-Term
  • Major Adverse Cardiovascular Events
  • Long Coronary Stent Implantation
03

In context

Lead sponsor

Sohag University is the lead sponsor of 1,218 studies on the registry; 627 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

This prospective multi-center observational cohort study will be conducted in the Cardiology Department on 650 patients.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age ≥18 years old.
  • Both sexes.
  • Patients undergo percutaneous coronary intervention (PCI) with successful implantation of a drug-eluting stent (DES) measuring ≥38 mm in length.
  • Successful stent deployment with discharge after PCI.

Exclusion criteria

Exclusion Criteria:

  • Bare-metal stent (BMS) implantation.
  • Cardiogenic shock at presentation.
  • In-stent restenosis lesions.
  • Previous stent implantation in the target coronary segment.
  • Life expectancy \<6 months due to non-cardiac causes.
  • Incomplete clinical or geographic data.
  • Patients lost to follow-up immediately after hospital discharge.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
650 participants (estimated)
Patient registry
No

Groups and cohorts

  • Geographic mismatch group

    Patients with geographic mismatch.

    Procedure: Coronary Stent Implantation

  • Non-geographic mismatch group

    Patients without geographic mismatch.

    Procedure: Coronary Stent Implantation

Interventions

  • ProcedureCoronary Stent Implantation

    Patients undergo percutaneous coronary intervention (PCI) with successful implantation of a drug-eluting stent (DES) measuring ≥38 mm in length

06

What researchers measure

Primary outcomes

  1. Incidence of Major Adverse Cardiovascular Events

    Incidence of Major Adverse Cardiovascular Events (MACE) will be recorded within 30 days post-percutaneous coronary intervention (PCI).

    Time frame: 30 days post-percutaneous coronary intervention

Secondary outcomes

  1. Incidence of all-cause mortality

    Incidence of all-cause mortality will be recorded within 60 days.

    Time frame: 60 days post-percutaneous coronary intervention

  2. Occurrence of myocardial infarction

    Number of participants who experience myocardial infarction following the index percutaneous coronary intervention (PCI).

    Time frame: 30 days post-percutaneous coronary intervention

  3. Occurrence of target lesion revascularization

    umber of participants who undergo repeat revascularization of the target lesion following the index percutaneous coronary intervention (PCI).

    Time frame: 30 days post-percutaneous coronary intervention

  4. Occurrence of definite stent thrombosis

    Number of participants who experience definite or probable thrombosis of the stent implanted during the index percutaneous coronary intervention (PCI).

    Time frame: 30 days post-percutaneous coronary intervention

  5. Hospital readmission

    Number of participants who are readmitted to a hospital following discharge from the index percutaneous coronary intervention (PCI) hospitalization.

    Time frame: 30 days post-percutaneous coronary intervention

  6. Length of index hospital stay

    Duration of the index hospitalization during which percutaneous coronary intervention (PCI) is performed, measured in days.

    Time frame: 60 days post-percutaneous coronary intervention

07

Study locations

1 of 1 sites recruiting
  • Sohag University
    Sohag, 82511, Egypt
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes — The data will be available upon a reasonable request from the corresponding author after the end of study for one year.

Supporting information: Study protocol

Time frame: After the end of study for one year.

Access criteria: The data will be available upon a reasonable request from the corresponding author.

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Sep 2026 (actual). Primary completion is estimated for May 2027, 8 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 18, 2026
First posted
Oct 22, 2026
StartActual
Sep 1, 2026
Primary completionEst.
May 1, 2027
CompletionEst.
May 1, 2027
Last update
Oct 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07890181
Lead sponsor
Sohag University
Responsible party
Remon Saleh Adly (Lecturer of Cardiovascular, Faculty of Medicine, Sohag University, Sohag, Egypt., Sohag University) — Principal investigator
First posted
Oct 22, 2026
Start date
Sep 1, 2026
Primary completion
May 1, 2027 (estimated)
Completion
May 1, 2027 (estimated)
Last update
Oct 22, 2026

Study contacts

Remon S Adly, MD
Contact
remonsaleh@yahoo.com
00201221878986

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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