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RecruitingNCT07885800Updated Oct 21, 2026

Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality

An observational study in Gall Bladder Carcinoma, sponsored by Sohag University. Recruiting at 1 site in Egypt. Open to participants aged 14 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-21.

Sponsored by Sohag University · Observational

From the registry’s dates

  • Started Sep 2026; still recruiting 1 month later.
Updated Oct 21, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
100
Ages
14 Years to 70 Years
Sex
All
01

Study summary

Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality

Read the detailed description

Gallstone disease represents one of the commonest benign biliary disorders encountered in general surgical practice, ranging from asymptomatic cholelithiasis to biliary colic, acute cholecystitis, chronic cholecystitis, pancreatitis, cholangitis, and obstructive jaundice. Laparoscopic cholecystectomy is widely accepted as the standard definitive treatment for symptomatic gallstone disease and constitutes one of the most frequently performed abdominal operations worldwide This study aims to determine the incidence of incidental gallbladder carcinoma among routine cholecystectomy specimens in Sohag and to evaluate its clinicopathological characteristics, associated risk factors, histopathological staging, and clinical significance regarding postoperative management, referral, and need for further surgical intervention.

02

Conditions studied

  • Gall Bladder Carcinoma

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Keywords

  • gall bladder carcinoma
03

In context

Gallbladder Neoplasms

255 studies on the registry are indexed under Gallbladder Neoplasms; 61 are open to participants now.

This study's planned enrollment of 100 is below the median of 230 across 54 observational studies indexed under Gallbladder Neoplasms.

Browse Gallbladder Neoplasms studies →

Lead sponsor

Sohag University is the lead sponsor of 1,218 studies on the registry; 627 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
14 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study will involve patients undergoing elective or emergency cholecystectomy at Sohag University Hospital for presumed benign gallbladder disease, including symptomatic cholelithiasis, acute calculous cholecystitis, chronic calculous cholecystitis, gallbladder mucocele, empyema, or gallbladder polyps without confirmed preoperative malignancy

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Patients undergoing cholecystectomy either lap or open or lap converted into open.
  2. Patients whose gallbladder specimens are available for complete histopathological examination.
  3. Patients who provide written informed consent to participate in the study.
  4. Patients of both sexes and all eligible adult age groups.

Exclusion criteria

Exclusion Criteria:

  1. Patients with preoperatively confirmed gallbladder carcinoma.
  2. Patients undergoing cholecystectomy as part of planned oncological surgery for another malignancy.
  3. Patients with missing, damaged, or inadequately preserved gallbladder specimens.
  4. Patients with incomplete clinical or histopathological data.
  5. Patients refusing participation or postoperative follow-up.

    -

05

Study design

Observational model
Cohort
Time perspective
Other
Enrollment
100 participants (estimated)
Target follow-up
6 Months
Patient registry
Yes

Groups and cohorts

  • all patient performed cholecystectomy

    Other: histopathology of gall bladder

Interventions

  • Otherhistopathology of gall bladder

    histopathology of gall bladder after cholycystectomy

06

What researchers measure

Primary outcomes

  1. incidence of gallbladder carcinoma

    incidence of gallbladder carcinoma in histopathology

    Time frame: 6 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided — Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Sep 2026 (actual). Primary completion is estimated for May 2027, 8 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 14, 2026
First posted
Oct 21, 2026
StartActual
Sep 20, 2026
Primary completionEst.
May 21, 2027
CompletionEst.
May 22, 2027
Last update
Oct 21, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 21, 2026
Show all 1 update
  1. Oct 21, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07885800
Lead sponsor
Sohag University
Responsible party
Yahia Khalaf Ahmed (yahia.abdelrasol@med.sohag.edu.eg, Sohag University) — Principal investigator
First posted
Oct 21, 2026
Start date
Sep 20, 2026
Primary completion
May 21, 2027 (estimated)
Completion
May 22, 2027 (estimated)
Last update
Oct 21, 2026

Study contacts

yahia kh ahmed, master
Contact
yahiakhalaf22@icloud.com
0201121838858
yahia kh ahmed, master
Contact
yahiakhalaf22@icloud.com
01121838858

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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