An observational study in Joint Contracture, Contracture and Cicatrix, sponsored by Universitas Sebelas Maret. Not yet recruiting. Per ClinicalTrials.gov, last updated 2026-10-21.
Sponsored by Universitas Sebelas Maret · Observational
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
A joint contracture is a tightening of scar tissue, most often after a deep burn, that limits how far a joint can move. Surgery can release the tight scar, but the contracture may return over time. Z-plasty rearranges nearby skin to lengthen the scar, while FTSG covers the released area with full-thickness skin taken from another part of the body. Previous studies have shown conflicting results about which technique has a lower risk of the contracture returning.
This study will review the medical records of patients who had contracture release surgery of the shoulder, elbow, wrist/hand, hip, knee, or ankle at Dr. Moewardi General Hospital, Surakarta, Indonesia, between 2016 and 2026. No new treatment or procedure will be given to patients, and all patient information will be kept anonymous.
The study hypothesis is that the rate of contracture recurrence differs between patients treated with Z-plasty and those treated with FTSG. The results may help surgeons choose the most suitable technique to reduce the risk of recurrence and improve patients' movement and quality of life.
Background Deep (full-thickness) burns over joints frequently lead to scar contractures that restrict range of motion (ROM), impair function and independence in daily activities, and reduce quality of life. Approximately one-third of burn patients have at least one contracture at hospital discharge. Despite surgical release, recurrence remains a clinical problem, with a pooled recurrence rate of about 10% reported for hand burn contractures. Z-plasty (local transposition flaps that lengthen the scar axis without donor tissue) and full-thickness skin graft (FTSG; coverage of the post-release defect with full-thickness skin from a donor site) are the two most commonly used techniques for releasing extremity contractures. Comparative evidence on recurrence is inconsistent: some studies report lower recurrence after Z-plasty and others report no significant difference. This variation may reflect differences in anatomical site, contracture morphology (linear band versus broad planar defect), burn severity, operative technique, rehabilitation adherence, and length of follow-up. Evidence specific to extremity joint contractures remains limited.
Objectives The primary objective is to compare the recurrence rate of extremity joint contracture after surgical excision/release with Z-plasty versus FTSG. Secondary objectives are to describe the demographic and clinical characteristics of patients in each group, to determine the recurrence rate within each group, and to identify factors associated with contracture recurrence.
Study Design This is a single-center, observational, analytic, retrospective cohort study based on review of existing medical records. Patients are grouped according to the closure technique documented in the operative report (Z-plasty alone or FTSG alone). Treatment allocation was determined by routine clinical care; no intervention is assigned or administered as part of this study.
Setting and Study Period Department of Plastic, Reconstructive and Aesthetic Surgery, Dr. Moewardi General Hospital / Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia. Medical records from 2016 to 2026 will be reviewed. Data collection and analysis are planned for July to November 2026.
Sampling Total (consecutive) sampling will be used: all patients meeting the eligibility criteria during the study period will be included, given the limited number of cases at a single institution. No formal a priori sample size calculation is performed.
Variables The exposure is the surgical technique (Z-plasty or FTSG). The outcome is contracture recurrence, defined as loss of the corrected ROM or development of a tethering scar band requiring revision, assessed by goniometric evaluation at least 6 to 12 months postoperatively. Potential confounders recorded include age, anatomical joint involved, depth of the initial burn, duration of follow-up, adherence to postoperative rehabilitation (physiotherapy, splinting, pressure garments), and comorbidities such as diabetes mellitus.
Data Collection and Management Data will be abstracted from medical records using a standardized, investigator-designed data collection form covering de-identified patient characteristics, clinical characteristics, operative technique, pre- and postoperative ROM, and recurrence status at the last recorded follow-up. Data will be verified and cleaned for completeness and internal consistency before analysis. Patients with incomplete records or loss to follow-up before the minimum recurrence-assessment period will be excluded, so the primary analysis will be a complete-case analysis.
Statistical Analysis Descriptive (univariate) statistics will summarize participant characteristics. Recurrence proportions between the Z-plasty and FTSG groups will be compared using the chi-square test, or Fisher's exact test when any expected cell count is less than 5. If appropriate, multivariable logistic regression will be performed to adjust for potential confounders. Statistical significance is set at p \< 0.05.
Ethics The study will be submitted for approval to the Health Research Ethics Committee of Dr. Moewardi General Hospital before data collection. Only secondary data from medical records are used, no direct intervention involves participants, and all data will be anonymized to protect patient confidentiality in accordance with Indonesian medical records regulations.
152 studies on the registry are indexed under Contracture; 22 are open to participants now.
This study's planned enrollment of 300 is above the median of 110 across 36 observational studies indexed under Contracture.
Browse Contracture studies →Universitas Sebelas Maret is the lead sponsor of 28 studies on the registry; 3 are open to participants now.
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Patients of all ages with extremity joint contracture, predominantly post-burn scar contracture, who underwent surgical contracture release with either Z-plasty or full-thickness skin graft at the Department of Plastic, Reconstructive and Aesthetic Surgery, Dr. Moewardi General Hospital, a tertiary referral hospital in Surakarta, Indonesia, between 2016 and 2026. Participants are identified retrospectively from hospital medical records.
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Exclusion Criteria:
Patients with extremity joint contracture (shoulder, elbow, wrist/hand, hip, knee, or ankle) who underwent surgical excision/release of the contracture with Z-plasty as the sole closure technique at Dr. Moewardi General Hospital between 2016 and 2026. Z-plasty involves transposition of two opposing triangular local flaps to lengthen the scar axis and reorient the scar without donor tissue. Data are obtained retrospectively from medical records; the procedure was performed as part of routine clinical care and was not assigned by the study.
Procedure: Z-Plasty
Patients with extremity joint contracture (shoulder, elbow, wrist/hand, hip, knee, or ankle) who underwent surgical excision/release of the contracture with full-thickness skin graft (FTSG) as the sole closure technique at Dr. Moewardi General Hospital between 2016 and 2026. FTSG involves covering the post-release defect with a graft containing the epidermis and full dermis harvested from a donor site. Data are obtained retrospectively from medical records; the procedure was performed as part of routine clinical care and was not assigned by the study.
Procedure: Full-Thickness Skin Graft
Surgical release of extremity joint contracture using Z-plasty as the sole closure technique. After incision/excision of the contracted scar band, two opposing triangular local flaps are transposed to lengthen the scar axis and reorient the scar along relaxed skin tension lines, without the need for donor-site tissue. Performed as part of routine clinical care; not assigned by the study.
Surgical release of extremity joint contracture by excision of the contracted scar, followed by coverage of the resulting defect with a full-thickness skin graft (epidermis and entire dermis) harvested from a donor site, used as the sole closure technique without combined local flap transposition. Performed as part of routine clinical care; not assigned by the study.
Rate of Contracture Recurrence
Proportion of participants with contracture recurrence in each group, defined as loss of the surgically corrected range of motion (ROM) or the development of a tethering scar band requiring revision surgery, as documented in medical records based on goniometric evaluation. Recurrence is recorded as a binary outcome (recurrence / no recurrence) and compared between the Z-plasty and FTSG groups.
Time frame: At least 6 months after surgery (assessed at last recorded follow-up)
No study locations are listed for this record.
Plan to share: No — Individual participant data will not be shared because the study uses retrospective medical record data from a single hospital, and sharing was not covered by the ethics approval (308/VII/HREC/2026) or by hospital medical record confidentiality regulations. Aggregate results will be reported in publications.
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Start is estimated for Oct 2026; primary completion for Jan 2027, 2 months later.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Universitas Sebelas Maret