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CompletedNCT07879521Updated Oct 19, 2026

PENG, Suprainguinal Fascia Iliaca Block, and Control After Total Hip Arthroplasty

An interventional study of Pericapsular nerve group (PENG) block and Suprainguinal Fascia Iliaca Plane Block in Total Hip Arthroplasty, Postoperative Pain, sponsored by Uludag University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-19.

Sponsored by Uludag University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 6 months after the study started (first participant enrolled Apr 2026, registered Oct 2026).
Updated Oct 19, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
99
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative pain and opioid requirements. However, these techniques may also affect muscle strength and early mobilization.

This randomized, controlled, prospective study compares the effects of PENG block, suprainguinal fascia iliaca plane block, and no regional block in patients undergoing total hip arthroplasty. Postoperative pain, opioid consumption, quadriceps muscle strength, and hip flexion are evaluated to compare the analgesic effectiveness and motor effects of these approaches.

02

Conditions studied

  • Total Hip Arthroplasty, Postoperative Pain

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Keywords

  • Total Hip Arthroplasty
  • PENG Block
  • Suprainguinal Fascia Iliaca Block
  • Postoperative Analgesia
  • Quadriceps Muscle Strength
03

In context

Pain, Postoperative

5,224 studies on the registry are indexed under Pain, Postoperative; 1,154 are open to participants now.

This study's enrollment of 99 is above the median of 75 across 4,457 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Uludag University is the lead sponsor of 145 studies on the registry; 39 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients who provided written informed consent
  • Patients aged 18 years or older
  • Patients with an American Society of Anesthesiologists (ASA) physical status of I, II, or III
  • Patients scheduled to undergo elective total hip arthroplasty

Exclusion criteria

Exclusion Criteria:

  • Patients who did not consent to participate in the study
  • Patients with ASA physical status IV or V
  • Patients using anticoagulant medication or with suspected coagulopathy
  • Patients with an allergy to local anesthetic agents
  • Patients with infection at the intended block site
  • Pregnant patients or patients with suspected pregnancy
  • Patients with severe neurological or psychiatric disorders
  • Patients with severe cardiovascular disease
  • Patients with chronic opioid use
  • Patients with hepatic insufficiency or renal failure (glomerular filtration rate \<15 mL/min/1.73 m²)
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
99 participants (actual)

Study arms

  • Experimental
    PENG Block Group

    Participants undergoing total hip arthroplasty received a pericapsular nerve group (PENG) block for postoperative analgesia.

    Procedure: Pericapsular nerve group (PENG) block

  • Experimental
    Suprainguinal Fascia Iliaca Block Group

    Participants undergoing total hip arthroplasty received a suprainguinal fascia iliaca plane block for postoperative analgesia.

    Procedure: Suprainguinal Fascia Iliaca Plane Block

  • No intervention
    Control Group

    Participants undergoing total hip arthroplasty did not receive a regional nerve block. Standard perioperative care and analgesia were provided according to the study protocol.

Interventions

  • ProcedurePericapsular nerve group (PENG) block

    Ultrasound-guided pericapsular nerve group (PENG) block performed for postoperative analgesia in patients undergoing total hip arthroplasty.

  • ProcedureSuprainguinal Fascia Iliaca Plane Block

    Ultrasound-guided suprainguinal fascia iliaca plane block performed for postoperative analgesia in patients undergoing total hip arthroplasty.

06

What researchers measure

Primary outcomes

  1. Postoperative Pain Scores

    Postoperative pain intensity was assessed using the visual analog scale (VAS), with scores recorded on a 0-100 mm scale. Pain scores were compared among the PENG block, suprainguinal fascia iliaca plane block, and control groups.

    Time frame: Up to 24 hours after surgery.

Secondary outcomes

  1. Quadriceps Muscle Strength

    Quadriceps muscle strength was assessed using manual muscle testing (MMT).

    Time frame: Up to 24 hours after surgery.

  2. Hip Flexion Angle

    Hip flexion angle was measured in degrees.

    Time frame: Up to 24 hours after surgery.

07

Study locations

1 site
  • Bursa Uludağ University Faculty of Medicine Hospital
    Bursa, Bursa, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 19, 2026
Show all 1 update
  1. Oct 19, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07879521
Lead sponsor
Uludag University
Responsible party
Berfin Altaş (Anesthesiology Resident, Uludag University) — Principal investigator
First posted
Oct 19, 2026
Start date
Apr 2, 2026
Primary completion
Sep 29, 2026
Completion
Sep 29, 2026
Last update
Oct 19, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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