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RecruitingNCT07870460PREDICTYOUTHUpdated Oct 15, 2026

Multimodal Machine Learning for Predicting Reduced Participation in Elite Youth Football

An observational study in Athletic Injury and Fatigue Recovery, sponsored by Palacky University. Recruiting at 1 site in Czechia. Open to male participants aged 15 Years to 19 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-15.

Sponsored by Palacky University · Observational

From the registry’s dates

  • Started Jul 2026; still recruiting 3 months later.
Updated Oct 15, 2026Primary outcomes revisedNewly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
30
Ages
15 Years to 19 Years
Sex
Male
01

Study summary

This study protocol describes a prospective longitudinal observational study designed to evaluate the accuracy of machine learning models in predicting the short-term (24-72 h) risk of reduced participation (training modification or absence due to health complaints, injury, or illness) among elite youth football players (categories U16 to U19).

Full participation in training and matches is a key determinant of athletic development and squad availability in elite youth football. Conventional injury surveillance typically reduces athlete availability to a binary time-loss state and overlooks the continuum on which athletes remain active despite emerging fatigue, minor musculoskeletal complaints, or functional limitations.

In this study, continuous multimodal monitoring integrates external training and match locomotion (Catapult Vector 10 Hz GNSS / 100 Hz IMU), nocturnal autonomic nervous regulation (WHOOP 5.0 wrist-worn photoplethysmography evaluating resting heart rate, heart rate variability RMSSD, and sleep architecture), daily subjective wellness (AMS Hooper Index: sleep quality, stress, fatigue, mood, and muscle soreness), weekly neuromuscular screening (VALD ForceDecks countermovement jumps and NordBord hamstring strength), and anthropometrics with biological maturation offset.

Participation status is adjudicated daily by designated coaching and medical staff. The primary objective is to develop, compare, and internally validate short-term prediction models for the onset transition from full participation to reduced participation, formulated as a single one-step discrete-time hazard read coherently across 24-, 48-, and 72-hour operational horizons. The study aims to evaluate explainable machine learning models (Survival XGBoost, GAMM with SHAP/LIME interpretation) to support training load management and injury risk mitigation within elite academies.

Read the detailed description

STUDY DESIGN AND COHORT:

This is a prospective, longitudinal, single-site observational cohort study conducted across one complete 10-month competitive season (2026/2027) within the U16 and U19 squads of an elite youth football academy (SK Sigma Olomouc, Czechia). The cohort comprises approximately 30 elite male youth football players. The unit of analysis is the at-risk player-day in full participation (longitudinal person-period array), yielding an estimated 6,000 to 8,000 observed player-days.

PRIMARY OUTCOME (TARGET VARIABLE):

The primary outcome is the staff-adjudicated transition event from full participation into any lower category of the daily participation gradient (modified training with >20% volume reduction, reduced training intensity, or complete absence due to medical/health reasons). Conditional on full participation on day t, the primary modeled quantity is the one-step discrete-time onset hazard. Operational cumulative onset probabilities are read coherently across 24-, 48-, and 72-hour horizons. To ensure outcome adjudication reliability, an inter-rater agreement analysis (Cohen's kappa) is performed between independent staff members.

MULTIMODAL PREDICTOR DOMAINS:

Candidate predictors span eight pre-specified canonical domains (\~31 candidate variables; \~33-36 parameters after categorical expansion):

  1. Player Profile \& Maturation: Baseline anthropometry, body composition (InBody 230: FFM, % body fat), and biological maturation offset (Mirwald equation).
  2. External Load: Catapult Vector GNSS/IMU metrics (total distance, high-speed running >20 km/h, sprinting >25.2 km/h, accelerations/decelerations >3.0 m/s², PlayerLoad).
  3. Internal Load: Daily heart rate telemetry and session-RPE derived metrics (training monotony and training strain).
  4. Autonomic Recovery \& Sleep: Continuously recorded overnight via WHOOP 5.0 wrist-worn wearable bands (resting heart rate, HRV RMSSD during slow-wave sleep, sleep architecture, and skin temperature).
  5. Neuromuscular Capacity: Repeated weekly neuromuscular screening on VALD Systems (ForceFrame hip adduction/abduction and NordBord eccentric/isometric hamstring strength and bilateral asymmetries).
  6. Performance Capacity: Periodic physical testing (sprint times, change of direction, and jump mechanics).
  7. Contextual Factors: Microcycle schedule (days to/from match day), match congestion, and playing position.
  8. Daily Subjective Wellness: Morning perceptual ratings on a 1-5 Likert scale (Hooper index: sleep, fatigue, stress, soreness). An objective-only sensitivity model will explicitly exclude subjective wellness to prevent construct overlap and circularity.

RESAMPLING AND LEAKAGE DISCIPLINE:

Model evaluation operates via a calendar-aligned rolling-origin cross-validation scheme with an expanding training window and temporally subsequent held-out test blocks. To prevent data leakage across the train/test boundary, an embedded temporal embargo of >=72 hours is implemented. All data-dependent preprocessing steps (imputation via MICE/PMM, scaling, dimensionality reduction) are fitted strictly within the training partition of each resample and applied to held-out test data.

STATISTICAL MODELLING AND EVALUATION:

Pre-specified candidate models include baseline logistic regressions, Generalised Additive Mixed Models (GAMM) with player-level random intercepts, and tree-based learners (Survival XGBoost with functional monotonicity constraints). Model evaluation follows a calibration-first hierarchy (Brier score, calibration slopes/curves), followed by discrimination under class imbalance (Precision-Recall AUC, Matthews Correlation Coefficient). Model behavior and domain contributions are interpreted using explainable artificial intelligence (XAI) frameworks (SHAP and LIME).

02

Conditions studied

  • Athletic Injury
  • Fatigue Recovery

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Keywords

  • injury prevention
  • machine learning
  • multimodal monitoring
  • catapult GPS
  • WHOOP HRV
  • VALD dynamometry
  • reduced participation
  • youth football
03

In context

Athletic Injuries

273 studies on the registry are indexed under Athletic Injuries; 43 are open to participants now.

This study's planned enrollment of 30 is below the median of 100 across 103 observational studies indexed under Athletic Injuries.

Browse Athletic Injuries studies →

Lead sponsor

Palacky University is the lead sponsor of 32 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 19 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Elite male youth football players (categories U16 and U19) registered in a licensed national youth football academy (SK Sigma Olomouc, Czechia) competing in top-tier national youth leagues.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Registered player in the U16 or U19 squad of an elite football academy (SK Sigma Olomouc).
  • At least three years of structured football training within an organized academy programme.
  • Regular active participation in microcycle team training and competitive league matches.
  • Written informed assent by the player and written informed consent by a parent or legal guardian (for minor participants).
  • Monitoring compliance rate > 80% during the initial 14-day passive run-in period.

Exclusion criteria

Exclusion Criteria:

  • Pre-existing severe musculoskeletal injury, orthopedic surgery, or neurological disorder preventing full participation at baseline.
  • Known cardiovascular, metabolic, or systemic disease contraindicating maximal athletic exertion.
  • Inability or refusal to wear continuous monitoring sensors (Catapult GNSS unit during training, WHOOP strap during sleep).
  • Prolonged absence from the squad due to non-medical administrative reasons (transfer, academic leave, disciplinary suspension).
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No

Groups and cohorts

  • Elite Youth Football Squads (U16 & U19)

    Approximately 30 registered male youth football players from U16 and U19 academy squads (SK Sigma Olomouc) undergoing regular training and competitive match microcycles with continuous multimodal monitoring across one full season.

06

What researchers measure

Primary outcomes

  1. Short-Term Incidence of Change in Participation Status (24, 48, and 72-Hour Discrete-Time Hazard)

    Daily morning consensus assessment (at 8:30 AM) of player participation recorded in the club Athlete Management System (AMS) on a 3-point ordinal scale: Full participation (0), Modified training with \>20% volume restriction or sprint restriction due to medical/health complaints (1), and Complete absence due to injury or illness (2). Transitions from full participation to modified training or absence (Levels 1 and 2) are modeled as a binary event of participation status change under a discrete-time survival framework with a 3-day clean washout period (W = 3) for re-entry into the risk set.

    Time frame: Daily assessments across one complete 10-month competitive football season (predicting transitions within 24, 48, and 72 hours).

07

Study locations

1 of 1 sites recruiting
  • SK Sigma Olomouc Academy & AC Baluo, Palacký University Olomouc
    Olomouc, 77900, Czechia
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

2 registry updates since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jul 2026 (actual). Primary completion is estimated for Jun 2027, 11 months after the start.

Of 40 non-industry observational studies under Athletic Injuries, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 2 and three quarters within 11. This study's planned 11 months is above that.

Counting every sponsor, half of 40 studies reached it within 7 months; a quarter within 2 and three quarters within 11.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 6, 2026
First posted
Oct 13, 2026
StartActual
Jul 15, 2026
Primary completionEst.
Jun 30, 2027
CompletionEst.
Jun 30, 2028
Last update
Oct 15, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Also revised
primary outcomes
Registered
First appeared on the registry
Oct 13, 2026
Show all 2 updates
  1. Oct 15, 2026
    Primary outcomes Revised (2 changes)
    + 3 other changes: identifiers, conditions and contact details
  2. Oct 13, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07870460
Lead sponsor
Palacky University
Responsible party
Karel Hulka (doc. Mgr., Ph.D., Head of Department, Palacky University) — Principal investigator
First posted
Oct 13, 2026
Start date
Jul 15, 2026
Primary completion
Jun 30, 2027 (estimated)
Completion
Jun 30, 2028 (estimated)
Last update
Oct 15, 2026

Study contacts

David Prycl
Contact
david.prycl@upol.cz
775111781
Karel Hulka, doc. Mgr., Ph.D.
study director · Palacky University Olomouc

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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