An observational study in Multiple Sclerosis, sponsored by Universitair Ziekenhuis Brussel. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-09.
Sponsored by Universitair Ziekenhuis Brussel · Observational
This study aims to evaluate the practical and research utility of a new test assessing language and memory in people with MS. To this end, we are administering the test to a group of 100 individuals with MS who are receiving treatment at the National MS Center Melsbroek.
These data will allow us to determine whether scores on the new test correlate with those of established cognitive tests. Subsequently, we will administer the new test to 100 individuals without an MS diagnosis who are matched for age, gender, and education level. This will enable us to assess whether there are significant differences in scores between individuals with MS and those without the diagnosis.
One year later, we will re-administer the tests to the participants with MS to determine the extent to which changes in scores on the new test correspond to changes in scores on established tests.
3,524 studies on the registry are indexed under Multiple Sclerosis; 668 are open to participants now.
This study's planned enrollment of 200 is above the median of 100 across 1,034 observational studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →Universitair Ziekenhuis Brussel is the lead sponsor of 374 studies on the registry; 106 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult people diagnosed with multiple sclerosis (PwMS), treated in a multidisciplinary rehabilitation program in the National Multiple Sclerosis Center (NMSC) Belgium.
Healthy (no MS diagnosis) adults matched for age, gender and education
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
For PwMS:
- MS relapse more recently than three months
Treated in a the National MS Center rehabilitation center
matched for age, gender and educational level
Language and Memory Test (LMT)
The LMT is a brief multidomain test assessing finger tapping speed, rapid lexical access, and visuospatial memory, designed for MS populations.
Time frame: Baseline, after one week and and after one year
Symbol Digit Modalities Test (SDMT)
Participants match symbols and digits as quickly as possible following standardized oral instruc-tions. The test measures processing speed and sustained attention.
Time frame: Baseline and after one year
Cognitive Change Scale (CCS)
The CCS assesses subjective cognitive changes over the past year and includes four validated subscales relevant to MS populations: general cognition, language and executive function, external feedback, and coping strategies.
Time frame: Baseline and after one year
No study locations are listed for this record.
Start is estimated for Oct 2026; primary completion for Feb 2028, 16 months later.
Of 341 non-industry observational studies under Multiple Sclerosis, half reached primary completion within 37 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 72. This study's planned 16 months is below that.
Counting every sponsor, half of 440 studies reached it within 41 months; a quarter within 15 and three quarters within 75.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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