An interventional study of Acacia arabica Mouth Rinse and acacia arabica paste in Gingival and Periodontal Disease, sponsored by Umm Al-Qura University. Completed at 1 site in Saudi Arabia. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-09-24.
Sponsored by Umm Al-Qura University · Not applicable, Interventional, and Treatment
This randomized clinical pilot study evaluated the short-term effects of Acacia arabica mouth rinse and paste as adjuncts to conventional oral hygiene in adults with plaque-induced gingivitis. Thirty systemically healthy participants aged 18-42 years were randomly allocated into three groups: a control group receiving conventional oral hygiene measures, an Acacia arabica mouth rinse group, and an Acacia arabica paste group. All participants received professional plaque removal and standardized oral hygiene instructions at baseline. Participants in the intervention groups additionally used either the Acacia arabica mouth rinse or paste twice daily for four weeks. Clinical assessments were performed at baseline, 2 weeks, and 4 weeks. The study evaluated changes in plaque index, gingival index, bleeding on probing, and salivary pH. The study aimed to determine whether Acacia arabica formulations could provide additional short-term benefits in plaque and gingival inflammation control compared with conventional oral hygiene measures alone.
Exclusion Criteria:
Participants received professional plaque removal at baseline and standardized oral hygiene instructions, including the modified Bass brushing technique. Participants were instructed to brush twice daily using a regular fluoridated toothpaste and received no Acacia arabica intervention during the 4-week study period.
Participants received professional plaque removal and standardized oral hygiene instructions at baseline. In addition, participants used 10 mL of Acacia arabica mouth rinse, prepared at a concentration of 1 g of extract per 10 mL of distilled water, twice daily after toothbrushing for 4 weeks. Participants were instructed to swish the solution for 1 minute, retain it intraorally for an additional 2 minutes, and then expectorate.
Other: Acacia arabica Mouth Rinse
Participants received professional plaque removal and standardized oral hygiene instructions at baseline. In addition, participants applied a pea-sized amount of Acacia arabica paste (Gumtone® gel) to the gingiva twice daily after toothbrushing for 4 weeks. The paste was gently massaged into the gingiva for approximately 2 minutes and subsequently removed using gauze.
Other: acacia arabica paste
the rinse as 1 g extract/10 mL distilled water
a pea-sized amount of Acacia arabica paste (Gumtone® gel)
Change in Gingival Index (GI)
Gingival inflammation was assessed using the Gingival Index at baseline, 2 weeks, and 4 weeks. The index was used to evaluate changes in the severity of gingival inflammation during the intervention period. Lower scores indicate less gingival inflammation and better gingival health.
Time frame: Baseline, 2 weeks, and 4 weeks
Change in Plaque Index (PI)
Plaque accumulation was assessed using the Plaque Index at baseline, 2 weeks, and 4 weeks. The index was used to quantify changes in dental plaque accumulation during the intervention period. Lower scores indicate less plaque accumulation and better plaque control.
Time frame: Baseline, 2 weeks, and 4 weeks
Documents are hosted by the registry — open the source record to download them.
Plan to share: No — Individual participant data are not planned to be publicly shared due to participant confidentiality and institutional ethical considerations. De-identified data supporting the findings may be made available from the corresponding investigator upon reasonable request and subject to institutional and ethical approval.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Umm Al-Qura University