An interventional study of Moringa Oleifera Leaf Powder in Prediabetes and Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), sponsored by Maranatha Christian University. Completed at 1 site in Indonesia. Open to participants aged 25 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-09-22.
Sponsored by Maranatha Christian University · Not applicable, Interventional, and Treatment
The goal of this clinical trial was to learn whether Moringa oleifera leaf powder could lower fasting blood glucose in adults aged 25 to 55 years with prediabetes. It also assessed unwanted health effects during the intervention. The main questions it aimed to answer were:
Researchers compared Moringa oleifera leaf powder with matching placebo capsules that contained no Moringa.
Participants:
This was a prospective, randomized, double-blind, placebo-controlled, parallel-group clinical trial conducted in a primary care setting in Bekasi, Indonesia. The study evaluated the effect of Moringa oleifera leaf powder on fasting blood glucose over 90 days in adults with prediabetes.
Eligible participants were adults aged 25 to 55 years with fasting blood glucose levels of 100-125 mg/dL who had not used oral antidiabetic medication or insulin during the preceding 3 months. After providing informed consent, 114 participants were randomly assigned in a 1:1 ratio to the Moringa oleifera leaf powder group or the placebo group.
Participants in the intervention group received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days. Participants in the control group received matching microcrystalline cellulose placebo capsules according to the same schedule.
Fasting blood glucose was measured at baseline and every 3 days through day 90. The primary objective was to compare the longitudinal pattern of fasting blood glucose between the two groups. Treatment adherence and unwanted health effects were also monitored throughout the study.
918 studies on the registry are indexed under Prediabetic State; 232 are open to participants now.
This study's enrollment of 114 is above the median of 62 across 762 interventional studies indexed under Prediabetic State.
Browse Prediabetic State studies →Maranatha Christian University is the lead sponsor of 3 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants received 2,400 mg of Moringa oleifera leaf powder daily as six 400-mg capsules, taken as two capsules three times daily after meals for 90 days.
Dietary Supplement: Moringa Oleifera Leaf Powder
Participants received six matching microcrystalline cellulose placebo capsules daily, taken as two capsules three times daily after meals for 90 days.
Dietary Supplement: Moringa Oleifera Leaf Powder
Standardized Moringa oleifera leaf powder provided in 400-mg oral capsules. Participants received 2,400 mg daily as two capsules three times daily after meals for 90 days.
Fasting Blood Glucose Level
Fasting blood glucose was measured in milligrams per deciliter (mg/dL) using a validated capillary blood glucose monitoring device. Repeated measurements were used to evaluate the fasting blood glucose trajectory and differences between the two treatment groups over the 90-day intervention.
Time frame: Baseline and every 3 days through Day 90 (31 time points).
Plan to share: No — There is currently no plan to share de-identified individual participant data with researchers outside the study team. Study findings will be disseminated in aggregate form through peer-reviewed publication.
No publications or documents are linked to this record.
Ran from Apr 2024 to primary completion in Aug 2024, 4 months.
Of 378 non-industry interventional studies with no phase under Prediabetic State, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 39. This study's 4 months is below that.
Counting every sponsor, half of 424 studies reached it within 23 months; a quarter within 11 and three quarters within 37.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Moringa oleifera leaf
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