An interventional study of Intervention C (Targeted skin cooling) and Intervention B (Ambient cooling) in Menopause Hot Flashes, sponsored by SRI International. Recruiting at 1 site in United States. Open to female participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by SRI International · Not applicable, Interventional, and Basic science
This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.
339 studies on the registry are indexed under Hot Flashes; 56 are open to participants now.
This study's planned enrollment of 40 is below the median of 90 across 306 interventional studies indexed under Hot Flashes.
Browse Hot Flashes studies →SRI International is the lead sponsor of 10 studies on the registry; 2 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
Postmenopausal
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Laboratory interventions are administered in the order of Room Temperature-Ambient Cooling-Targeted skin cooling
Other: Intervention C (Targeted skin cooling) · Other: Intervention B (Ambient cooling) · Other: Intervention A (Room temperature)
Laboratory interventions are administered in order of Ambient cooling-Targeted skin cooling-Room temperature
Other: Intervention C (Targeted skin cooling) · Other: Intervention B (Ambient cooling) · Other: Intervention A (Room temperature)
Laboratory interventions are administered in the order of Targeted skin cooling-Room temperature-Ambient cooling
Other: Intervention C (Targeted skin cooling) · Other: Intervention B (Ambient cooling) · Other: Intervention A (Room temperature)
Cooling targeted to the skin during a hot flash
Cooling of the room
Control condition (room temperature)
Number of hot flashes
Number of hot flashes, based on sternal skin conductance measurement
Time frame: Across the ~5 hour experimental period in the lab
Plan to share: Undecided
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SRI International