An observational study in Gastrointestinal Hemorrhage and Critical Illness, sponsored by Assiut University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-16.
Sponsored by Assiut University · Observational
This prospective cohort study aims to determine the prevalence of gastrointestinal bleeding among critically ill patients admitted to intensive care units, identify independent risk factors, and describe clinical outcomes including ICU length of stay, transfusion requirements, and mortality at Assiut University Hospitals.
Gastrointestinal bleeding is a serious complication in critically ill patients and is associated with increased morbidity and mortality. This prospective observational cohort study will include adult patients (≥18 years) admitted to the intensive care units of Assiut University Hospitals.
Patients will be followed during their ICU stay for the occurrence of clinically important gastrointestinal bleeding (overt or occult) occurring ≥24 hours after admission. Clinical, laboratory, and treatment-related data will be collected to identify independent risk factors and to assess associated clinical outcomes.
Adult patients (≥18 years) admitted to the intensive care units of Assiut University Hospitals.
Exclusion Criteria:
Adult patients admitted to the intensive care units who will be followed for the occurrence of ICU-acquired gastrointestinal bleeding and its associated risk factors and outcomes.
Incidence of clinically important ICU-acquired gastrointestinal bleeding
Proportion of critically ill patients who develop clinically important gastrointestinal bleeding (overt bleeding with hemodynamic compromise or significant hemoglobin drop, or occult bleeding confirmed by fecal occult blood test or endoscopy) occurring 24 hours or more after ICU admission.
Time frame: Up to 30 days
Independent risk factors for gastrointestinal bleeding
Odds ratios of clinical, laboratory, and treatment-related factors for the occurrence of clinically important gastrointestinal bleeding using multivariable logistic regression analysis.
Time frame: Up to 30 days
ICU length of stay
Duration of intensive care unit stay in days.
Time frame: Up to 30 days
Blood transfusion requirement
Number of units of packed red blood cells transfused during the ICU stay.
Time frame: Up to 30 days
ICU mortality
Proportion of patients who die during the ICU stay.
Time frame: Up to 30 days
Need for endoscopic or surgical intervention
Proportion of patients requiring endoscopic therapy or surgical intervention for gastrointestinal bleeding.
Time frame: Up to 30 days
No study locations are listed for this record.
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Assiut University