ClinicalTrials.gg
RecruitingNCT07822360Updated Sep 16, 2026

Prevalence of Polyendocrine Metabolic Ovarian Syndrome in Patients Diagnosed With Acne Vulgaris in Sohag University Hospital

An observational study in Polyendocrine Metabolic Ovarian Syndrome and Acne Vulgaris, sponsored by Sohag University. Recruiting at 1 site in Egypt. Open to female participants aged 15 Years to 49 Years. Per ClinicalTrials.gov, last updated 2026-09-16.

Sponsored by Sohag University · Observational

From the registry’s dates

  • Started Aug 2026; still recruiting 3 months later.

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Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
90
Ages
15 Years to 49 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 39 studies in Acne Vulgaris with a site in Egypt — 10 open to participants now, 11 under way, 2 of them phase 3. Acne Vulgaris · Egypt.

Started
2026
with 3 others
Observational
8 of 39
3 open now
Primary completion
2027-02
later than 8 of 10 live
Registered
37th of 39
by date
Lead sponsor
7 of 39
Sohag University

Among the 39 studies in Acne Vulgaris with a site in Egypt, this one is one of 4 that started in 2026, is one of 8 observational ones, reaches primary completion later than 8 of the 10 other live ones, and was the 37th registered.

Acne Vulgaris

791 studies on the registry are indexed under Acne Vulgaris; 94 are open to participants now.

Browse Acne Vulgaris studies →

Open to participants now

10 of the 39 studies in Acne Vulgaris with a site in Egypt are open now. Recruiting first, the newest first:

4 more — sign in →

All 10 open studies →

A study can be open while its sites in Egypt have not opened yet or have stopped. Only those recruiting at a site in Egypt →

Who these studies take

Of the 47 Acne Vulgaris studies recruiting now, 17 (36%) set no upper age limit and 29 (62%) stop at 75 or younger; 21 take children under 18; 17 take healthy volunteers.

This study: 15 Years to 49 Years · female · no healthy volunteers.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 39 studies in Acne Vulgaris with a site in Egypt, or all of them as a file.
02

Study summary

The aim of this study is to determine the prevalence of polyendocrine metabolic ovarian syndrome (PMOS) among female patients diagnosed with acne vulgaris in Sohag university hospital

Read the detailed description

A cross-sectional observational study designed to determine the prevalence of polycystic ovary syndrome (PCOS) among patients diagnosed with acne vulgaris attending Sohag University Hospital.

03

Conditions studied

  • Polyendocrine Metabolic Ovarian Syndrome
  • Acne Vulgaris

Browse trials for

Keywords

  • Polyendocrine metabolic ovarian syndrome
  • Acne vulgaris
  • PMOS
04

Who can participate

Ages eligible
15 Years to 49 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Female patients diagnosed with acne vulgaris

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Female patients at childbearing age ( 15 - 49 years) (World Health, 2024).
  • Patients clinically diagnosed with acne vulgaris.

    • Clinical diagnosis of Acne vulgaris:

    o Presence of comedones (open/black and closed/white), inflammatory lesions (papules, pustules, or nodules), with or without post-acne changes such as hyperpigmentation or scarring (Oge et al., 2019).

  • Patients diagnosed with polyendocrine metabolic ovarian syndrome (PMOS) according to the 2023 International Evidence-based Guideline for PCOS diagnosis.
  • Diagnostic criteria for PMOS diagnosis in adults : (Forslund et al., 2024).

    • Diagnosis of PMOS will be based on the presence of at least two of the following three criteria after exclusion of other etiologies:

      1. Ovulatory dysfunction:

      • Irregular menstrual cycles or oligo/anovulation. 2. Clinical and/or biochemical hyperandrogenism:
      • Clinical signs such as hirsutism and/or acne, or biochemical evidence of elevated androgen levels.

        3. Polycystic ovarian morphology (PCOM):

      • Polycystic ovaries detected by pelvic ultrasound, or elevated anti-Müllerian hormone (AMH) level in adults as an alternative to ultrasound.
    • Most women with PMOS have a combination of hyperandrogenism and irregular cycles, and in these cases there is no need to assess PCOM. In adolescents, both ovulatory dysfunction and hyperandrogenism are mandatory (Forslund et al., 2024).
  • Patients willing to participate and provide .

Exclusion criteria

Exclusion Criteria:

  • Pregnant women.
  • Lactating mothers
  • Women diagnosed with other acneiform lesions
  • Women on certain drug treatments like oral pills, ovarian stimulating drugs and oral hypoglycemic agents like metformin.
  • Patients with incomplete clinical data or who refuse to participate in the study.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
90 participants (estimated)
Patient registry
No

Groups and cohorts

  • Patients diagnosed with acne vulgaris
06

What researchers measure

Primary outcomes

  1. Prevalence of polyendocrine metabolic ovarian syndrome (PMOS) among patients diagnosed with acne vulgaris in Sohag university hospital

    Time frame: Over 1 year

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Zhuang C, Luo X, Wang W, Sun R, Qi M, Yu J. Cardiovascular Risk According to Body Mass Index in Women of Reproductive Age With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2022 Feb 16;9:822079. doi: 10.3389/fcvm.2022.822079. eCollection 2022. PubMed 35252398 ↗
  • Vasam M, Korutla S, Bohara RA. Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances. Biochem Biophys Rep. 2023 Nov 23;36:101578. doi: 10.1016/j.bbrep.2023.101578. eCollection 2023 Dec. PubMed 38076662 ↗
  • Teede HJ, Khomami MB, Morman R, Laven JSE, Joham AE, Costello MF, Patil M, Rees DA, Berry L, Cree MG, Zhao H, Norman RJ, Dokras A, Piltonen T; Global Name Change Consortium. Polyendocrine metabolic ovarian syndrome, the new name for polycystic ovary syndrome: a multistep global consensus process. Lancet. 2026 Jun 6;407(10545):2329-2339. doi: 10.1016/S0140-6736(26)00717-8. Epub 2026 May 12. PubMed 42119588 ↗
  • Taieb A, Feryel A. Deciphering the Role of Androgen in the Dermatologic Manifestations of Polycystic Ovary Syndrome Patients: A State-of-the-Art Review. Diagnostics (Basel). 2024 Nov 16;14(22):2578. doi: 10.3390/diagnostics14222578. PubMed 39594244 ↗
  • Stener-Victorin E, Teede H, Norman RJ, Legro R, Goodarzi MO, Dokras A, Laven J, Hoeger K, Piltonen TT. Polycystic ovary syndrome. Nat Rev Dis Primers. 2024 Apr 18;10(1):27. doi: 10.1038/s41572-024-00511-3. PubMed 38637590 ↗
  • Ruth KS, Day FR, Tyrrell J, Thompson DJ, Wood AR, Mahajan A, Beaumont RN, Wittemans L, Martin S, Busch AS, Erzurumluoglu AM, Hollis B, O'Mara TA; Endometrial Cancer Association Consortium; McCarthy MI, Langenberg C, Easton DF, Wareham NJ, Burgess S, Murray A, Ong KK, Frayling TM, Perry JRB. Using human genetics to understand the disease impacts of testosterone in men and women. Nat Med. 2020 Feb;26(2):252-258. doi: 10.1038/s41591-020-0751-5. Epub 2020 Feb 10. PubMed 32042192 ↗
  • Pourhoseingholi MA, Vahedi M, Rahimzadeh M. Sample size calculation in medical studies. Gastroenterol Hepatol Bed Bench. 2013 Winter;6(1):14-7. PubMed 24834239 ↗
  • Pakornphadungsit K, Harnchoowong S, Wattanakrai P. Evaluation of an Acne Severity Grading Self-Assessment System Suitable for the Thai Population - A Pilot Study. Clin Cosmet Investig Dermatol. 2023 Nov 3;16:3171-3179. doi: 10.2147/CCID.S427648. eCollection 2023. PubMed 37941850 ↗
  • Ollila MM, Hoek A, Piltonen TT. The association between polycystic ovary syndrome and early cardiovascular disease morbidity strengthens. Eur J Endocrinol. 2023 Jul 20;189(1):R4-R5. doi: 10.1093/ejendo/lvad083. No abstract available. PubMed 37461221 ↗
  • Oge' LK, Broussard A, Marshall MD. Acne Vulgaris: Diagnosis and Treatment. Am Fam Physician. 2019 Oct 15;100(8):475-484. PubMed 31613567 ↗
  • Liu Q, Tang B, Zhu Z, Kraft P, Deng Q, Stener-Victorin E, Jiang X. A genome-wide cross-trait analysis identifies shared loci and causal relationships of type 2 diabetes and glycaemic traits with polycystic ovary syndrome. Diabetologia. 2022 Sep;65(9):1483-1494. doi: 10.1007/s00125-022-05746-x. Epub 2022 Jun 30. PubMed 35771237 ↗
  • Hoeger KM, Dokras A, Piltonen T. Update on PCOS: Consequences, Challenges, and Guiding Treatment. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1071-e1083. doi: 10.1210/clinem/dgaa839. PubMed 33211867 ↗
  • Hazarika N. Acne vulgaris: new evidence in pathogenesis and future modalities of treatment. J Dermatolog Treat. 2021 May;32(3):277-285. doi: 10.1080/09546634.2019.1654075. Epub 2019 Aug 29. PubMed 31393195 ↗
  • Forslund M, Melin J, Stener-Victorin E, Hirschberg AL, Teede H, Vanky E, Piltonen T. International evidence-based guideline on assessment and management of PCOS-A Nordic perspective. Acta Obstet Gynecol Scand. 2024 Jan;103(1):7-12. doi: 10.1111/aogs.14725. Epub 2023 Nov 20. PubMed 37983875 ↗
  • Doshi A, Zaheer A, Stiller MJ. A comparison of current acne grading systems and proposal of a novel system. Int J Dermatol. 1997 Jun;36(6):416-8. doi: 10.1046/j.1365-4362.1997.00099.x. No abstract available. PubMed 9248884 ↗
  • Conforti C, Giuffrida R, Fadda S, Fai A, Romita P, Zalaudek I, Dianzani C. Topical dermocosmetics and acne vulgaris. Dermatol Ther. 2021 Jan;34(1):e14436. doi: 10.1111/dth.14436. Epub 2020 Nov 15. PubMed 33084158 ↗
  • Baldwin H, Farberg A, Frey C, Hartman C, Lain E, Meltzer R, Draelos Z. Unmet Needs in the Management of Acne Vulgaris: A Consensus Statement. J Drugs Dermatol. 2023 Jun 1;22(6):582-587. doi: 10.36849/JDD.7587. PubMed 37276154 ↗
  • Ach T, Guesmi A, Kalboussi M, Ben Abdessalem F, Mraihi E, El Mhabrech H. Validation of the follicular and ovarian thresholds by an 18-MHz ultrasound imaging in polycystic ovary syndrome: a pilot cutoff for North African patients. Ther Adv Reprod Health. 2024 Aug 20;18:26334941241270372. doi: 10.1177/26334941241270372. eCollection 2024 Jan-Dec. PubMed 39170801 ↗
  • BLIEDE, K., ROUMIA, A. H. & KHADDAM, J. 2020. Prevalence of Polycystic Ovary Syndrome in Women with Acne Vulgaris. Asian Journal of Research in Dermatological Science, 3, 5-13.
  • JABEEN, S., ASAD, F., RANI, Z., KHURSHID, K. & PAL, S. S. 2018. Frequency of polycystic ovarian syndrome among patients presenting with acne. Journal of Pakistan Association of Dermatologists, 28, 329-332

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Aug 2026 (actual). Primary completion is estimated for Feb 2027, 5 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 10, 2026
First posted
Sep 16, 2026
StartActual
Aug 9, 2026
Primary completionEst.
Feb 8, 2027
CompletionEst.
May 2027
Last update
Sep 16, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07822360
Lead sponsor
Sohag University
Responsible party
Omar Shazly Saleh (Dermatology, Venereology and Andrology resident, Sohag University) — Principal investigator
First posted
Sep 16, 2026
Start date
Aug 9, 2026
Primary completion
Feb 8, 2027 (estimated)
Completion
May 2027 (estimated)
Last update
Sep 16, 2026

Study contacts

Omar Shazly Saleh, Resident
Contact
oshazly399@gmail.com
+201004861933

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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