An interventional study of Ankle Evertor and Invertor Strength Training in Ankle Rehabilitation, Ankle Instability and Ankle Sprain, sponsored by University of Ljubljana. Completed at 1 site in Slovenia. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by University of Ljubljana · Not applicable, Interventional, and Prevention
The aim of this study was to investigate the effects of a 12-week ankle evertor and invertor strength training program performed on a specially designed device, which allows isolated strengthening of evertor and invertor muscles. Outcome measures included isometric ankle torque, EMG activity of six tibial muscles, muscle coactivation, and kinematic parameters during three walking conditions. This trial was retrospectively registered. The study was conducted in 2017 as part of a doctoral dissertation at the Faculty of Sport, University of Ljubljana, prior to the authors' awareness of prospective registration requirements.
350 studies on the registry are indexed under Ankle Injuries; 74 are open to participants now.
This study's enrollment of 32 is below the median of 54 across 270 interventional studies indexed under Ankle Injuries.
Browse Ankle Injuries studies →University of Ljubljana is the lead sponsor of 43 studies on the registry; 9 are open to participants now.
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Participants performed a 12-week ankle evertor and invertor strength training program on a specially designed device.
Behavioral: Ankle Evertor and Invertor Strength Training
Participants maintained habitual activity without any structured strength training.
Participants in experimental group were performing strength training on a specially designed device. The program consisted of 8 weeks of hypertrophy-oriented training followed by 4 weeks of neural activation training.
Isometric Ankle Torque
Maximal isometric torque in foot eversion and inversion direction measured with a isometric device.
Time frame: Baseline and 12 weeks
EMG Activity of Tibial Muscles
Monitoring normalized RMS EMG amplitude of peroneus longus, peroneus brevis, tibialis anterior, gastrocnemius medialis, gastrocnemius lateralis, and soleus during different walking conditions.
Time frame: Baseline and 12 weeks
Walking Speed
Monitoring walking speed (m/s) during three walking conditions.
Time frame: Baseline and 12 weeks
Stretch Reflex Response
Electromyographic reflex response of ankle evertor (m. PL and PB) and invertor muscles (m TA) following mechanical perturbation.
Time frame: Baseline and 12 weeks
Muscle Co-activation Index Between Pairs of Tibial Muscles During Walking
Coactivation index (%) calculated between pairs of tibial muscles (PL, PB, TA, SOL, GM, GL) during three different types of walking (normal walking, medially inclined, laterally inclined surface).
Time frame: Baseline and 12 weeks
Foot Position During Walking
Monitoring foot elevation angle (degrees) during three different types of walking.
Time frame: Baseline and 12 weeks
Contact Time
Monitoring contact time (s) during three different types of walking (flat surface, medially inclined laterally inclined).
Time frame: Baseline and 12 weeks
Stride Length
Monitoring stride length (m) during three different types of walking (flat surface, medially inclined, laterally inclined).
Time frame: Baseline and 12 weeks
Plan to share: Yes — Individual participant data may be shared upon reasonable request to the corresponding author.
Supporting information: Informed consent form
Time frame: Following publication of study results
Ran from Feb 2017 to primary completion in May 2017, 3 months.
Of 138 non-industry interventional studies with no phase under Ankle Injuries, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 30. This study's 3 months is below that.
Counting every sponsor, half of 141 studies reached it within 9 months; a quarter within 4 and three quarters within 31.
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This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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University of Ljubljana