An interventional study of Anteromedial Injection and Anterolateral Injection in Osteoarthitis, Osteoarthritic Knee Pain and Osteoarthritis (OA), sponsored by University of Chicago. Recruiting at 5 sites in United States. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2026-09-04.
Sponsored by University of Chicago · Not applicable, Interventional, and Treatment
The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee. Participants will:
3,292 studies on the registry are indexed under Osteoarthritis, Knee; 623 are open to participants now.
This study's planned enrollment of 140 is above the median of 68 across 2,714 interventional studies indexed under Osteoarthritis, Knee.
Browse Osteoarthritis, Knee studies →University of Chicago is the lead sponsor of 924 studies on the registry; 185 are open to participants now.
Of its 103 completed or terminated interventional studies of FDA-regulated products, 72 (70%) have results posted.
Compared within Osteoarthritis, Knee, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Osteoarthritis. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
These patients will receive their corticosteroid injections on their anterolateral knees.
Procedure: Anterolateral Injection
This group of patients will receive injections on the anteromedial side of their knee.
Procedure: Anteromedial Injection
If randomized to this intervention, patients will receive a corticosteroid injection in the anteromedial side of their knee.
If randomized to this intervention, patients will receive a corticosteroid injection on the anterolateral side of their knee.
Numeric Pain Rating Scale
This survey asks patients to rate their pain on a scale from 0 to 10.
Time frame: Pre-procedure, 2 weeks, 6 weeks, and 12 weeks post-injection
Knee Osteoarthritis and Outcome Score-Joint Replacement
This standardized survey asks patients to describe the impact of their knee stiffness and pain on daily tasks.
Time frame: Pre-procedure, 2 weeks, 6 weeks, and 12 weeks post-injection
Institutional Survey on Satisfaction with Injection
This survey asks patients to rate their satisfaction with their corticosteroid injection on a scale from 0 to 10.
Time frame: 2 weeks, 6 weeks, and 12 weeks post-injection
Patient Global Impression of Change
This survey asks patients to rate their overall health status on a scale from 1 to 7.
Time frame: 2 weeks, 6 weeks, and 12 weeks post-injection
Plan to share: Undecided — IPD may not be shared due to privacy concerns, but the authors will consider sharing de-identified data upon reasonable request.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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