ClinicalTrials.gg
RecruitingNCT07803510Updated Sep 9, 2026

Presurgical Illustration and Psychological Stress in Mandibular Third Molar Surgery

An interventional study of Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery in Psychological Stress, sponsored by Delta University for Science and Technology. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 32 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-09.

Sponsored by Delta University for Science and Technology · Not applicable, Interventional, and Screening

From the registry’s dates

  • Started Sep 2026; still recruiting 2 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
18 Years to 32 Years
Sex
All
01

Study summary

The aim of this clinical trial is to evaluate the influence of presurgical patient's diagrammatic illustration of mandibular third molar (Wisdom tooth) surgery on degrees of psychological stress.

Read the detailed description

Psychological stress is a common factor accompanied with surgeries in most situations, and mandibular third molar (Wisdom tooth (WT)) surgery couldn't be an exception. Saliva was proven as a valid carrier that could be used to track the levels of cortisol representing the degree of patient's provoked stress. Patient orientation and presurgical diagrammatic illustration of the steps of WT surgery are very important aspects for patient preparation, yet, may be potential stress triggers as well.

This study aims to figure out if patients are exposed to illustrations that shows the mandibular third molar surgery before having the surgery would aggravate their stress or may relieve it considering orientation and relative absence of fear of unknown.

02

Conditions studied

  • Psychological Stress

Browse trials for

Keywords

  • Psychological Stress
  • Emotional Stress
  • Salivary Cortisol
  • Third Molar Extraction
03

In context

Stress, Psychological

844 studies on the registry are indexed under Stress, Psychological; 136 are open to participants now.

This study's planned enrollment of 80 is close to the median of 84 across 688 interventional studies indexed under Stress, Psychological.

Browse Stress, Psychological studies →

Lead sponsor

Delta University for Science and Technology is the lead sponsor of 86 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 32 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy patients ( Class I),
  • Patients demanding extraction of their mandibular third molar,
  • Mandibular third molars requiring flap raising, bone removal, coronal and radicular sectioning (Modified Parant Scale Class IV),
  • Patients accepting their saliva sampling prior to and after surgery.

Exclusion criteria

Exclusion Criteria:

  • Acutely painful mandibular third molars on clinical examination,
  • Pericoronal and/or active periapical and/or active periodontal pathologies on clinical and radiographic examinations,
  • Patients using ,
  • Psychiatric patients,
  • Smokers,
  • Pregnant patients, and/or those observing their menstruation,
  • Patients with conditions of altered cortisol secretion (such as Addison's disease, Cushing's syndrome, and congenital adrenal hyperplasia),
  • Patients with altered secretion of saliva (such as due to using atropine, calcium channel blockers, antidepressants, antihistamines, Sjogren's syndrome, and radiotherapy).
  • Patients who are overtly anxious about dental treatment (scoring >19 on the Modified Dental Anxiety Scale).
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

ASA physical status

The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
80 participants (estimated)

Study arms

  • No intervention
    Control Group (No Presurgical Illustration)

    Patients in this group will have their mandibular third molar surgery done without having prior exposure to presurgical diagrammatic illustration for their surgery.

  • Active comparator
    Study Group (Presurgical Illustration)

    Patients in this group will have their mandibular third molar surgery done after having prior exposure to presurgical diagrammatic illustration for their surgery.

    Other: Presurgical Diagrammatic Illustration for Mandibular Third Molar Surgery

Interventions

  • OtherPresurgical Diagrammatic Illustration for Mandibular Third Molar Surgery

    The handling surgeon will show the patient (in the study group) a diagrammatic illustration for surgical steps of mandibular third molar extraction. This diagrammatic illustration includes flap raising, bone guttering, coronal and radicular tooth sectioning, and flap closure.

06

What researchers measure

Primary outcomes

  1. Salivary Cortisol Level (in ng/mL)

    Amount of salivary cortisol found in patients' saliva is considered directly proportional to degree of psychological stress.

    Time frame: 45 minutes before surgery, and 30 minutes after surgery.

Secondary outcomes

  1. Duration of Surgery (in minutes)

    Time taken for each surgery will be recorded starting from flap incision to end of last closing suture knot.

    Time frame: Same time of surgery

07

Study locations

1 of 1 sites recruiting
  • Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology
    Al Mansurah, Addakahlyia 35516, Egypt
    Recruiting
    • Mohammad Abdelhamid, PhD · Contacthamidsurgeon@gmail.com · 00201002285659
    • Mohammad Abdelhamid, PhD · Principal investigator
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Sep 2026 (actual). Primary completion is estimated for Nov 2026, 2 months after the start.

Of 457 non-industry interventional studies with no phase under Stress, Psychological, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 26. This study's planned 2 months is below that.

Counting every sponsor, half of 470 studies reached it within 13 months; a quarter within 5 and three quarters within 26.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 31, 2026
First posted
Sep 3, 2026
StartActual
Sep 5, 2026
Primary completionEst.
Nov 2026
CompletionEst.
Nov 2026
Last update
Sep 9, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07803510
Lead sponsor
Delta University for Science and Technology
Responsible party
Sponsor
First posted
Sep 3, 2026
Start date
Sep 5, 2026
Primary completion
Nov 2026 (estimated)
Completion
Nov 2026 (estimated)
Last update
Sep 9, 2026

Study contacts

Mohammad Abdelhamid, PhD
Contact
hamidsurgeon@gmail.com
00201002285659
Mohammad Abdelhamid, PhD
principal investigator · Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Delta University for Science and Technology

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion