An interventional study of Chia Seed (Salvia hispanica L.) Beverage in Overweight Adults, Postprandial Glycemia and Appetite Response, sponsored by University of Veterinary and Animal Sciences, Lahore - Pakistan. Not yet recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-01.
Sponsored by University of Veterinary and Animal Sciences, Lahore - Pakistan · Not applicable, Interventional, and Prevention
Overweight and obesity affect nearly 2.5 billion adults worldwide and increase cardiometabolic risk. Postprandial glucose excursions are influenced by diet and inactivity and predict metabolic disorders, while South Asians, particularly Pakistanis, are more vulnerable due to genetic and lifestyle factors and processed diets. This study evaluates the impact of chia seed (Salvia hispanica L.) ingestion on postprandial glycemia and appetite in overweight adults, supporting UN Sustainable Development Goal 3 (Good Health and Well-being).
A randomized controlled crossover trial will be conducted among 30 overweight adults (BMI 25-29.9 kg/m²), aged 18-40 years. Participants will undergo control and intervention phases separated by a 14-day washout. The control beverage will contain 50 g glucose in 250 mL water, while the intervention beverage will contain the same beverage supplemented with 30 g chia seeds. Glucose response will be assessed using incremental area under the curve (iAUC) by the trapezoidal method, with appetite response also evaluated. Data will be analyzed using SPSS version 25; baseline characteristics will be presented as mean ± SD, and between-group differences will be assessed using a linear mixed model at p \< 0.05. Chia seed ingestion is expected to reduce postprandial blood glucose and improve appetite control.
3,599 studies on the registry are indexed under Overweight; 852 are open to participants now.
This study's planned enrollment of 30 is below the median of 78 across 3,120 interventional studies indexed under Overweight.
Browse Overweight studies →University of Veterinary and Animal Sciences, Lahore - Pakistan is the lead sponsor of 27 studies on the registry; 13 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will consume a standardized control beverage containing 50 g glucose dissolved in 250 mL water, with no chia seeds. Postprandial blood glucose and appetite responses will be assessed following consumption.
Dietary Supplement: Chia Seed (Salvia hispanica L.) Beverage
Participants will consume a standardized beverage containing 50 g glucose dissolved in 250 mL water supplemented with 30 g chia seeds (Salvia hispanica L.). Postprandial blood glucose and appetite responses will be assessed following consumption.
Dietary Supplement: Chia Seed (Salvia hispanica L.) Beverage
Participants will consume a standardized beverage containing 50 g glucose dissolved in 250 mL water, without chia seeds or any other fiber-containing ingredient. This beverage will serve as the control condition for comparison with the chia seed-supplemented glucose beverage.
Also known as: Glucose Beverage
Postprandial Blood Glucose
Incremental area under the blood glucose curve (iAUC) will be calculated from capillary blood glucose concentrations measured using a portable blood glucose meter (glucometer) from finger-prick blood samples at baseline (0 minutes) and at 15, 30, 45, 60, 90, and 120 minutes following beverage consumption. The iAUC will be calculated using the trapezoidal method over the 120-minute postprandial period, with fasting baseline glucose concentration used as the reference. Areas below the baseline will not contribute to the iAUC. The iAUC will be expressed in mmol·min/L. A lower iAUC indicates a lower overall postprandial glycemic response over 120 minutes. The change in iAUC between the intervention (50 g glucose + 30 g chia seeds) and control (50 g glucose) beverages will be compared.
Time frame: 5 weeks
Appetite Response
Appetite will be assessed using 100-mm Visual Analog Scales for hunger, fullness, desire to eat, and prospective food consumption. Each scale ranges from 0 to 100 mm. For hunger, desire to eat, and prospective food consumption, 0 indicates the lowest intensity ("not at all"/"nothing at all") and 100 indicates the highest intensity ("extremely"/"an extremely large amount"); higher scores indicate greater appetite. For fullness, 0 indicates not at all full and 100 indicates extremely full; higher scores indicate greater fullness and better appetite suppression.
Time frame: 5 weeks
Plan to share: No — Individual participant data will not be shared with other researchers due to participant confidentiality and privacy considerations. Only aggregated, de-identified study results will be reported and shared.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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University of Veterinary and Animal Sciences, Lahore - Pakistan