An Exploratory Study to Evaluate Skin Brightening Effects of Different Cosmetic Formulations on UV Irradiated Tanning Model

• Healthy Chinese female or male, aged from 18 to 50 years old (both inclusive).
• Participants in good health condition as per the health history questionnaire with no disease state or physical condition that the investigator believes could interfere with the interpretation of the data.
• Participant is able to read, understand and sign an appropriate informed consent form indicating his willingness to participate.
• ITA° range 10-42°; Skin type III and IV included and can tolerance 2MED radiation.
• No history of allergic diseases or allergies to cosmetics, UV light and other topical preparations.
• No history of photosensitive diseases and no recent use of medications that affect photosensitivity.
• The test area skin (back) should be free of birthmarks, inflammation, scars, excessive hair, etc.
• No cuts, abrasions, fissures, wounds, lacerations on the test site (back).
• Participants must understand the trial process, voluntarily participate in the study, and sign a written informed consent form.
• Willing to attend the study center twice daily for product application during the study period and complete all visits.

Exclusion Criteria:

• Study participants are employees of Sponsor or CRO.
• The study participants participated in test involving the test site within 2 months prior to the start of this test or are currently participating in such tests.
• Study participants had any other visible signs of local irritation, erythema, or skin disease on the visible parts of the body.
• Study participants consider they are prone to breakouts and/or sensitive skin.
• Study participants had a chronic illness or had major surgery in the past year.
• Study participants were receiving any skin treatments on the test sites.
• Study participants had allergies or sensitivities to cleansing products, creams/emulsion, costume jewelry, or other things.
• Female study participants were pregnant/breastfeeding or planning to become pregnant during the trial (study participants self-declared at screening visits).
• Study participants took medication for any condition, which the researchers believe may have affected the interpretation of the data.
• Study participants had a history of psoriasis, eczema, atopic dermatitis, severe acne, etc. Or have other chronic systemic diseases.
• Study participants had received oral or topical corticosteroids and other anti-inflammatory drugs within the last 1 month.
• Study participants used tartaric acid, salicylic acid and any other products or drugs that affect skin colour (such as hydroquinones) within the last 2 months.
• Study participants used retinoic acid preparations or aesthetic treatment such as chemical stripping, laser, pulsed light, etc. in the test site in the past three months.
• Study participants were inevitably exposed to prolonged sunlight.
• Clinical evaluation considers that participants are not suitable for the test.