An interventional study of TAP Block in Postoperative Pain, Acute, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-08-24.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Among 132 studies in Pain, Postoperative by Cairo University — 32 open to participants now, 32 under way, 1 of them phase 3. Pain, Postoperative · Cairo University.
Among the 132 studies in Pain, Postoperative by Cairo University, this one is the 43rd largest by planned enrollment of the 128 interventional ones that give a count, is one of 17 that started in 2026, is one of 91 with no phase, reaches primary completion later than 16 of the 31 other live ones, and was the 128th registered.
5,640 studies on the registry are indexed under Pain, Postoperative; 1,230 are open to participants now.
Browse Pain, Postoperative studies →32 of the 132 studies in Pain, Postoperative by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Cairo University · Sites in Egypt
Cairo University · Sites in Egypt
Cairo University · Sites in Egypt
Cairo University · Sites in Egypt
By country, each count listing its studies:
Of the 679 Pain, Postoperative studies recruiting now, 241 (35%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.
This study: 18 Years to 40 Years · all sexes · no healthy volunteers.
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132 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 8 · Phase 2 7 · Phase 3 10 · Phase 4 15
First in 2014; this study’s year is marked. 17 started in 2026.
This study's planned enrollment of 60 is below the median of 75 across 4,821 interventional studies indexed under Pain, Postoperative.
Median enrollment 50 across the 128 interventional studies, 54 across the 4 observational. Of the 57 that completed or were terminated, 1 (2%) have results posted.
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Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
7 of the studies in Pain, Postoperative by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07542795Cairo UniversityEvaluating The Use of CGF Plugs in Fresh Odontectomy Socket. | 2026-12-01 |
| NCT07618065Cairo University"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema" | 2027-02-01 |
| NCT07446868Cairo UniversityUltrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy | 2027-03-01 |
| NCT07654556Cairo UniversityInvestigating the Analgesic Efficacy and Ease of Perfomance of Modified Throracoabdominal Plane Block and Comparing it With Erector Spinea Plane Block in Laparacopic Sleeve Gasterctomy Surgeries | 2027-03-30 |
| NCT07787221Cairo UniversityQL Block Versus EO Plane Block for Analgesia After Open Nephrectomy | 2027-04-01 |
Among the 132 studies in Pain, Postoperative by Cairo University, from their registry updates:
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The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries. Forty adults (18-60 years, ASA I-II) will be randomly assigned to receive either TAP or ESPB after induction of general anesthesia. Postoperative pain will be assessed using the Visual Analogue Scale (VAS) and total fentanyl consumption over 24 hours. Secondary outcomes include time to first analgesic request, hemodynamic parameters, patient satisfaction, and incidence of complications. The study will be conducted at Cairo University Hospitals following ethical approval, with all patients providing written informed consent.
This randomized controlled trial aims to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries. Forty adults (18-60 years, ASA I-II) will be randomly assigned to receive either TAP or ESPB after induction of general anesthesia.
Preoperative assessment will include medical and surgical history, clinical examination, and routine laboratory investigations.
Intraoperative management will follow standard monitoring with general anesthesia, and the block will be performed under ultrasound guidance using 0.25% bupivacaine, bilaterally. TAP block will be performed at the anterolateral abdominal wall, while ESPB will be performed at the T8-T9 level in lateral decubitus position. The anesthesiologist performing the block will not participate in postoperative data collection, and outcome assessors will be blinded.
Postoperative pain management includes IV paracetamol every 8 hours and rescue fentanyl boluses (25 μg IV) if VAS ≥4, with a maximum total dose of 0.2-0.4 mg in 24 hours. Pain will be measured using the Visual Analogue Scale (VAS) at PACU, 2, 4, 6, 12, 18, and 24 hours. Secondary outcomes include time to first analgesic request, hemodynamic parameters, patient satisfaction, and incidence of adverse events such as PONV, hypotension, bradycardia, urinary retention, LAST, pneumothorax, or failed block.
Primary outcome: total fentanyl consumption in the first 24 hours postoperatively.
Secondary outcomes: time to first rescue analgesia, VAS scores, hemodynamic stability, patient satisfaction, and complications. The study will be conducted at Cairo University Hospitals after ethical committee approval, with all patients providing written informed consent. Data will be analyzed using SPSS v26, with parametric and non-parametric tests, repeated-measures ANOVA for VAS over time, Kaplan-Meier analysis for time to rescue analgesia, and chi-square or Fisher's exact test for categorical outcomes.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion criteria:
TAP block will be done under ultrasound-guidance with linear multi-frequency 6-13 MHz transducer probe and 21 G (0.514mm) needle inserted in-plane from medial to lateral, advanced through the fascial layers until the tip reaches the fascial plane between the internal oblique and the transversus abdominis muscle. After negative aspiration, 20 ml of 0.25% bupivacaine will be injected. Correct spread will be confirmed by separation of the fascial plane under ultrasound guidance. TAP block will be applied bilaterally.
Procedure: TAP Block
a high-frequency linear ultrasound probe will be placed in a longitudinal parasagittal orientation over the transverse process at the T8-T9 level. A 21G needle will be advanced in-plane to reach the fascial plane deep to the erector spinae muscle and superficial to the transverse process. After negative aspiration, 20 ml of 0.25% bupivacaine (Sunnypivacaine®, Sunny pharmaceuticals, Egypt) will be injected incrementally to ensure correct spread of local anesthetic in the ESP plane.
Procedure: TAP Block
a bilateral ultrasound guided TAP block performed by injecting 20 ml of 0.25% bupivacaine into the TAP space after negative aspiration. a bilateral ultrasound guided ESP block performed by injecting 20 ml of 0.25% bupivacaine into the ESP space after negative aspiration.
Also known as: ESP Block
Total fentanyl consumption.
Total fentanyl consumption in the first 24 hours (μg-microgram) postoperative.
Time frame: 24 hours.
Time to first rescue analgesia.
Time elapsed from the end of surgery until the patient requires the first dose of rescue analgesia.
Time frame: 24 hours postoperatively.
Postoperative Pain scores.
pain assessment using Visual Analog Scale (VAS) score: pain level scored from 0 (no pain) to 10 (worst imaginable pain).
Time frame: At Post Anesthesia Care Unit (PACU) and 2,4,6,12,18,24 hours Postoperatively.
Hemodynamic Parameter Heart rate
Heart rate
Time frame: At PACU and 1,2,4,6,12,24 hours postoperatively.
Hemodynamic Parameter
mean arterial blood pressure
Time frame: At PACU and 1,2,4,6,12,24 hours postoperatively.
Hemodynamic Parameter oxygen saturation
oxygen saturation
Time frame: At PACU and 1,2,4,6,12,24 hours postoperatively.
Patient Satisfaction.
Degree of patients' satisfaction.
Time frame: 24 hours postoperatively.
Incidence of postoperative complications.
Incidence of complications as hypotension, bradycardia, respiratory depression, pneumothorax and urine retention.
Time frame: within 24 hours postoperatively.
Plan to share: No
No publications or documents are linked to this record.
Started Jan 2026 (actual). Primary completion is estimated for Aug 2026, 7 months after the start.
Of 2,089 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's planned 7 months is below that.
Counting every sponsor, half of 2,102 studies reached it within 11 months; a quarter within 6 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
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