An interventional study of Xp Finisher R file in Endodontic Inflammation, sponsored by Minia University. Recruiting at 1 site in Egypt. Open to participants aged 13 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-21.
Sponsored by Minia University · Not applicable, Interventional, and Treatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth. When conventional root canal treatment fails, endodontic retreatment is often the preferred option, as it represents one of the most conservative approaches.
Endodontic retreatment involves removing old root canal filling material followed by cleaning, shaping, and refilling the canals. It may be associated with postoperative pain due to periapical tissue irritation and apical extrusion of debris during instrumentation.
Endodontic retreatment involves removing old root canal filling material followed by cleaning, shaping, and refilling the canals. It may be associated with postoperative pain due to periapical tissue irritation and apical extrusion of debris during instrumentation.
Also, the retreatment procedure plays a critical role in enhancing periapical healing and improving long-term outcomes in failed initial treatments.
Activation of irrigants during endodontic retreatment enhances the removal of residual gutta-percha, sealers, and debris, especially in lateral canals and complex areas. It also boosts disinfectant effectiveness, improving canal cleanliness and retreatment outcomes.
Ultrasonic activation uses high frequency vibrations to enhance irrigant penetration and fluid dynamics during endodontic retreatment. It improves the removal of residual filling materials and debris more effectively than conventional irrigation. The technique promotes cavitation and acoustic streaming, boosting disinfectant effectiveness and reducing bacterial load. Overall, ultrasonic activation enhances canal cleaning and contributes to better retreatment outcomes.
XP endo Finisher R is a specialized endodontic instrument designed for retreatment to improve removal of residual root filling materials from canals that conventional files cannot fully clean, especially in oval or curved anatomies. It uses flexible MaxWire alloy that expands in the canal, increasing contact with walls and enhancing removal of remnants and debris. Studies using micro CT imaging show that XP endo Finisher R significantly reduces filling material volume compared to some conventional techniques and is effective as a supplementary step after primary retreatment files .
CBCT provides three dimensional imaging that allows more accurate assessment of periapical healing and detection of residual pathology following endodontic retreatment compared with conventional 2 D radiographs. It is more sensitive in identifying persistent apical lesions and missed anatomy that may impact retreatment success. CBCT evaluation can influence clinical decision making and treatment planning by revealing details not seen in traditional imaging.
Systematic reviews show CBCT based outcome assessments often report different success rates due to this increased diagnostic sensitivity. Overall, CBCT contributes to a more comprehensive evaluation of retreatment outcomes and helps guide management further.
Despite the increasing use of irrigation activation techniques during endodontic retreatment, limited clinical evidence exists comparing XP-endo Finisher R with ultrasonic activation regarding postoperative pain and periapical healing outcomes.
316 studies on the registry are indexed under Pulpitis; 90 are open to participants now.
This study's planned enrollment of 34 is below the median of 64 across 288 interventional studies indexed under Pulpitis.
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Exclusion Criteria:
About 17 cases suffering from caries then the Caries will be removed with a sterile stone will undergo Xp Shaper R file for irrigation activation during retreatment procedure
Procedure: Xp Finisher R file
About 17 cases suffering from caries then the Caries will be removed with a sterile stone will undergo Ultrasonic activation of irrigation activation during retreatment procedure
Procedure: Xp Finisher R file
to evaluate the incidence and severity of postoperative pain using a numeric rating scale at 24, 48, and 72 hours and periapical healing via CBCT following retreatment with two different irrigation activation techniques: 1. Xp Finisher R file activation of irrigation. 2. Ultrasonic activation of irrigation.
Also known as: Ultrasonic activation
Post Operative Pain
Assessing the post operative pain measured by a numerical pain rating scale (NRS) where the level of pain will be recorded as follows: 0 reading represents "no pain" ; 1- 3 reading represents "mild pain" ; 4- 6 reading represents "moderate pain" and 7- 10 reading representative sever pain.
Time frame: from 6 hours to 48 hours after the procedure
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