An interventional study of Conventional Physical Therapy Program and Mulligan technique in Chronic Neck Pain, sponsored by Prof. Mosab Saleem Hamed Amoudi. Completed at 1 site in Palestinian Territories. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-08-14.
Sponsored by Prof. Mosab Saleem Hamed Amoudi · Not applicable, Interventional, and Treatment
This randomized controlled trial was conducted to evaluate the effectiveness of adding Mulligan Mobilization with Movement (MWM) to conventional physiotherapy in patients with chronic mechanical neck pain. Seventy-six participants aged 18-65 years were randomly assigned to receive either conventional physiotherapy alone or conventional physiotherapy combined with MWM for four weeks. Pain intensity, cervical range of motion, and functional disability were assessed before and after the intervention. The study aimed to compare changes in pain intensity, cervical range of motion, and functional disability between the two treatment groups.
Chronic mechanical neck pain is a common musculoskeletal condition associated with neck pain, reduced cervical mobility, and functional limitations. Conventional physiotherapy is commonly used in the management of chronic mechanical neck pain. Mulligan Mobilization with Movement (MWM) is a manual therapy technique that combines sustained joint mobilization with active movement and may be used as an adjunct to conventional physiotherapy.
This randomized controlled trial was conducted to investigate the effect of adding Mulligan Mobilization with Movement (MWM) to conventional physiotherapy in individuals with chronic mechanical neck pain.
A total of 76 participants aged 18 to 65 years were initially enrolled in the study. Six participants were excluded before randomization according to the study eligibility criteria. The remaining 70 participants were randomly allocated to one of two treatment groups: a control group receiving conventional physiotherapy alone (n = 32) and an experimental group receiving conventional physiotherapy combined with Mulligan Mobilization with Movement (n = 38).
Both groups received treatment three times per week for four consecutive weeks. The control group received the conventional physiotherapy program specified in the study protocol. The experimental group received the same conventional physiotherapy program with the addition of Mulligan Mobilization with Movement.
The primary outcome measures included pain intensity, cervical range of motion, and functional disability. Pain intensity was assessed using the Visual Analog Scale (VAS). Cervical range of motion was measured using goniometry. Functional disability related to neck pain was assessed using the Neck Disability Index (NDI).
Outcome measures were assessed at baseline and following completion of the four-week intervention period. The outcome measures were used to compare changes between the two treatment groups.
Statistical analysis was performed using analysis of covariance (ANCOVA), with adjustment for baseline measurements. Effect sizes were calculated using Cohen's d and partial eta squared (η²) to quantify the magnitude of between-group differences.
The study was designed as a randomized controlled trial to compare conventional physiotherapy alone with conventional physiotherapy combined with Mulligan Mobilization with Movement in individuals with chronic mechanical neck pain.
1,360 studies on the registry are indexed under Neck Pain; 299 are open to participants now.
This study's enrollment of 76 is above the median of 50 across 1,116 interventional studies indexed under Neck Pain.
Browse Neck Pain studies →Prof. Mosab Saleem Hamed Amoudi is the lead sponsor of 2 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Other: Conventional Physical Therapy Program
Other: Conventional Physical Therapy Program · Other: Mulligan technique
Included of Cervical mobility and strengthening exercises, Transcutaneous Electrical Nerve Stimulation (TENS) and Soft tissue massage
The Mulligan Concept is a manual therapy approach developed by New Zealand physiotherapist Brian Mulligan in the 1980s. It includes techniques such as Mobilization with Movement (MWM) and the Sustained Natural Apophyseal Glide (SNAG), which have attracted significant attention for their effectiveness in treating neck pain.
Also known as: Mulligan Concept
Change from baseline in pain intensity measured by Visual Analog Scale (VAS)
Pain intensity will be measured using the Visual Analog Scale (VAS), a 0-10 cm scale, where 0 indicates no pain and 10 indicates the worst pain. Higher scores indicate greater pain intensity and therefore worse outcomes. Pain intensity will be assessed at baseline and at the end of the 4-week intervention. The change in pain score from baseline to post-intervention will be reported.
Time frame: Before treatment (baseline) and 4 weeks (end of treatment)
Change from baseline in cervical range of motion (ROM) measured by goniometer (degrees)
Cervical range of motion (ROM) will be measured in degrees (°) using a goniometer at baseline and at the end of the 4-week intervention. Cervical flexion, extension, rotation, and lateral flexion will be assessed. The change in cervical ROM from baseline to post-intervention will be reported. Greater cervical ROM within the expected physiological range indicates better cervical mobility.
Time frame: Before treatment (baseline) and 4 weeks (end of treatment)
Change from baseline in neck-related disability measured by the Neck Disability Index (NDI)
Neck-related disability will be assessed using the Neck Disability Index (NDI), a 10-item self-reported questionnaire. Each item is scored from 0 to 5, with a total score ranging from 0 to 50. Higher scores indicate greater neck-related disability and therefore worse outcomes. The NDI will be administered at baseline and at the end of the 4-week intervention. The change in total NDI score from baseline to post-intervention will be reported.
Time frame: Before treatment (baseline) and 4 weeks (end of treatment)
Plan to share: No
No publications or documents are linked to this record.
Ran from Feb 2026 to primary completion in May 2026, 3 months.
Of 763 non-industry interventional studies with no phase under Neck Pain, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 3 and three quarters within 15. This study's 3 months is below that.
Counting every sponsor, half of 772 studies reached it within 7 months; a quarter within 3 and three quarters within 15.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Prof. Mosab Saleem Hamed Amoudi