An interventional study of Dual-Task-Based High-Amplitude Functional Exercise Program and Traditional Balance and Mobility Exercise Group in Mild Cognitive Impairment (MCI) and Exercises, sponsored by Istinye University. Not yet recruiting. Open to participants aged 65 Years to 85 Years. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by Istinye University · Not applicable, Interventional, and Treatment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment. A total of 36 participants aged 65 years and older will be randomly assigned to either a high-amplitude functional exercise group or a traditional balance and mobility exercise group. Both groups will participate in exercise sessions four times per week for four weeks, with each session lasting 60 minutes. The effects of the exercise programs will be evaluated by assessing balance, functional mobility, dual-task performance, walking performance, fear of falling, and independence in daily activities before and after the intervention.
3,872 studies on the registry are indexed under Cognitive Dysfunction; 1,119 are open to participants now.
This study's planned enrollment of 36 is below the median of 64 across 2,794 interventional studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →Istinye University is the lead sponsor of 221 studies on the registry; 94 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
NYHA class (heart failure)
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Dual-Task-Based High-Amplitude Functional Exercise Program
Other: Traditional Balance and Mobility Exercise Group
Participants will receive a dual-task-based high-amplitude functional exercise program consisting of high-amplitude functional movements combined with progressively challenging cognitive tasks. The program will be administered 4 times per week for 4 weeks, for a total of 16 sessions, with each session lasting 60 minutes. Exercise intensity will be prescribed as maximal effort, corresponding to 7-8/10 on the Borg Rating of Perceived Exertion Scale. The program will include seated and standing functional exercises, large-amplitude stepping movements, dynamic movements, large-amplitude walking, functional task activities, and complex functional tasks.
Participants will receive a traditional balance and mobility exercise program administered 4 times per week for 4 weeks, for a total of 16 sessions, with each session lasting 60 minutes. Exercise intensity will be moderate, corresponding to 4-5/10 on the Borg Rating of Perceived Exertion Scale. The program will consist of motor tasks without cognitive dual-task components.
Dual-Task Timed Up and Go Test
The Dual-Task TUG will assess functional mobility under cognitive load by adding a cognitive task to the standard Timed Up and Go test. Test performance will be recorded as the time required to complete the task.
Time frame: Baseline to post-intervention (4 weeks)
Mini-BESTest
The Mini-BESTest will be used to assess balance performance across anticipatory postural control, reactive postural control, sensory orientation, and dynamic gait. The scale consists of 14 items scored from 0 to 2, with a maximum total score of 28. Higher scores indicate better balance performance.
Time frame: Baseline to post-intervention (4 weeks)
Five Times Sit-to-Stand Test
The Five Times Sit-to-Stand Test will be used to assess lower-extremity muscle strength and functional capacity. The time required to complete five full sit-to-stand repetitions will be recorded.
Time frame: Baseline to post-intervention (4 weeks)
Timed Up and Go Test (TUG)
The TUG will be used to assess functional mobility and dynamic balance.
Time frame: Baseline to post-intervention (4 weeks)
Edinburgh Visual Gait Score
The EVGS will be used to assess gait quality through observational analysis of gait kinematics across different anatomical segments.
Time frame: Baseline to post-intervention (4 weeks)
Dual-Task Walking Speed
Walking speed will be measured during a cognitive dual-task condition over a 10-meter walking course and recorded in meters per second.
Time frame: Baseline to post-intervention (4 weeks)
Dual-Task Cost
Dual-task cost will be calculated from the TUG performance using the formula.
Time frame: Baseline to post-intervention (4 weeks)
Falls Efficacy Scale-International I
The FES-I will be used to assess concerns about falling during daily activities. Higher scores indicate greater fear of falling.
Time frame: Baseline to post-intervention (4 weeks)
Barthel Index
The Barthel Index will be used to assess independence in basic activities of daily living, including eating, bathing, dressing, and transfers. Scores range from 0 to 100, with higher scores indicating greater independence.
Time frame: Baseline to post-intervention (4 weeks)
Global Change Scale
The Global Change Scale will be used to assess participants' perceived change following the intervention. Participants will rate perceived change from -5 (much worse) to +5 (much better).
Time frame: Post-intervention (4 weeks)
No study locations are listed for this record.
Start is estimated for Aug 2026; primary completion for Apr 2027, 7 months later.
Of 1,442 non-industry interventional studies with no phase under Cognitive Dysfunction, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 51. This study's planned 7 months is below that.
Counting every sponsor, half of 1,511 studies reached it within 27 months; a quarter within 12 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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