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CompletedNCT07755475Updated Aug 10, 2026

A Clinical Trial to Evaluate the Effects of a Supplement on Cognitive Function and Energy Levels

An interventional study of Cellular Hydration Supplement in Cognitive Function, Fatigue and Energy Levels, sponsored by Artah Nutrition Limited. Completed at 1 site in United States. Open to participants aged 25 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-10.

Sponsored by Artah Nutrition Limited · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Not applicable
Ages
25 Years to 60 Years
Sex
All
01

Study summary

This study evaluates the effects of Artah's Cellular Hydration electrolyte supplement on cognitive function and energy levels in healthy adults aged 25-60 who experience mild to moderate fatigue, brain fog, or related symptoms. The trial is a single-arm, unblinded, virtual study in which all 50 participants will use the test product daily for 4 weeks.

Participants will complete self-reported questionnaires at Baseline, Week 1, Week 2, Week 3, and Week 4, and will undergo cognitive battery testing at Baseline and Week 4. The primary endpoint is change in cognitive performance scores as measured by a standardized cognitive battery. Secondary endpoints include participants' self-reported perceptions of mental clarity, alertness, mood, physical performance, overall energy levels, and frequency of food cravings.

02

Conditions studied

  • Cognitive Function
  • Fatigue
  • Energy Levels
  • Mental Clarity
  • Brain Fog
  • Food Cravings
03

Who can participate

Ages eligible
25 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Be male or female.
  • Be aged 25-60.
  • Anyone currently experiencing mild to moderate issues with at least three of the following: low energy or fatigue
  • difficulty concentrating or low mental sharpness
  • experiences of brain fog or lack of mental clarity
  • feeling of low productivity
  • muscle weakness
  • unwanted food cravings.
  • Undertakes moderate to high-intensity exercise such as jogging/running and/or heavy resistance training at least three times per week.
  • Willing to refrain from taking any products, medications, or supplements that target energy, cognition, or physical performance during the test period.
  • Anyone with a BMI 18.5 to 30.
  • Anyone who has access to a device (e.g., smartphone, laptop, computer) for reliable internet.
  • Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
  • Anyone willing to maintain a consistent diet and physical activity throughout study duration.

Exclusion criteria

Exclusion Criteria:

  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.
  • Anyone suffering from gastrointestinal disorders including but not limited to small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and celiac disease.
  • Anyone suffering from hyperkalemia (high potassium), liver disease, or kidney disease.
  • Anyone taking ACE inhibitors or potassium-sparing diuretics, examples include: Spironolactone (Aldactone), Eplerenone (Inspra), Amiloride (Midamor), Triamterene (Maxzide), Lisinopril (Zestril, Prinivil), Enalapril (Vasotec), Ramipril (Altace), Benazepril (Lotensin), Quinapril (Accupril), Losartan (Cozaar), Valsartan (Diovan), Olmesartan (Benicar), Irbesartan (Avapro), Lithium carbonate (Lithobid, Eskalith).
  • Anyone taking antibiotics.
  • Anyone with any allergies or sensitivities to any of the study product ingredients.
  • Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
  • Anyone unwilling to follow the study protocol.
  • Anyone with a history of substance abuse.
  • Anyone who is a shift worker with an irregular sleep-wake cycle.
  • Anyone who drinks heavily (8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men).
  • Anyone who is currently a smoker or has been a smoker in the past 3 months.
  • Currently partaking in another research study, or planning to at any point during this study's duration.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (actual)

Study arms

  • Active comparator
    Cellular Hydration Supplement

    Dietary Supplement: Cellular Hydration Supplement

Interventions

  • Dietary supplementCellular Hydration Supplement

    All 50 participants receive the Artah Cellular Hydration electrolyte supplement taken twice daily (once in the morning before the first meal and once in the afternoon after lunch or before evening exercise) as one teaspoon (approximately 7 g) stirred into 750 ml of water for 4 weeks.

05

What researchers measure

Primary outcomes

  1. Change in Cognitive Battery Test Score (Polygons)

    Change in processing speed and information sorting ability assessed via the Polygons timed cognitive battery subtest

    Time frame: Baseline and Week 4

  2. Change in Cognitive Battery Test Score (Double Trouble)

    Change in selective attention and processing speed assessed via the Double Trouble timed cognitive battery subtest (Stroop-based)

    Time frame: Baseline and Week 4

  3. Change in Cognitive Battery Test Score (Feature Match)

    Change in focus and processing speed assessed via the Feature Match timed cognitive battery subtest

    Time frame: Baseline and Week 4

  4. Change in Cognitive Battery Test Score (Paired Associates)

    Change in memory recall assessed via the Paired Associates performance-based cognitive battery subtest

    Time frame: Baseline and Week 4

  5. Change in Cognitive Battery Test Score (Digit Span)

    Change in short-term memory and cognitive flexibility assessed via the Digit Span performance-based cognitive battery subtest

    Time frame: Baseline and Week 4

  6. Change in Cognitive Battery Test Score (Spatial Planning)

    Change in executive function and logical decision-making assessed via the Spatial Planning timed cognitive battery subtest

    Time frame: Baseline and Week 4

Secondary outcomes

  1. Change in Self-Reported Mental Clarity and Focus

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

  2. Change in Self-Reported Alertness

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

  3. Change in Self-Reported Mood

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

  4. Change in Self-Reported Physical Performance

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

  5. Change in Self-Reported Overall Energy Levels

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

  6. Change in Self-Reported Frequency of Food Cravings

    Assessed via self-reported questionnaire

    Time frame: Baseline, Week 1, Week 2, Week 3, and Week 4

06

Study locations

1 site
  • Citruslabs
    Las Vegas, Nevada 89101, United States
07

Registry details

Key details

Study ID
NCT07755475
Lead sponsor
Artah Nutrition Limited
Collaborators
Citruslabs
Responsible party
Sponsor
First posted
Aug 10, 2026
Start date
Jun 13, 2025
Primary completion
Aug 16, 2025
Completion
Aug 16, 2025
Last update
Aug 10, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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