An interventional study of Self-etch adhesive and One-Step Adhesive in Malaligned Teeth and Crowding of Teeth, sponsored by Foundation University Islamabad. Not yet recruiting at 1 site in Pakistan. Open to participants aged 12 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-10.
Sponsored by Foundation University Islamabad · Not applicable, Interventional, and Prevention
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
The aim of this study is to compare the number of white spot lesions that appear around bonded brackets between self-etch and one-step bonding systems using visual examination and to compare amount of demineralisation using DIAGNOdent scores.
88 studies on the registry are indexed under Crowding; 22 are open to participants now.
This study's planned enrollment of 34 is close to the median of 36 across 74 interventional studies indexed under Crowding.
Browse Crowding studies →Foundation University Islamabad is the lead sponsor of 255 studies on the registry; 142 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Self- Etch Adhesive
Combination Product: Self-etch adhesive
Conventional bonding technique
Combination Product: Conventional Bonding Technique
Combination Product: One-Step Adhesive
Self-Etch adhesive used for two step bonding of bracket placement.
Placement of bracket using one-step adhesive system.
Bonding brackets using three step conventional technique; etchant , bonding agent, composite adhesive
Number of white spot lesions
Time frame: From bracket placement to 6 months after placement.
Demineralisation of bonded teeth
Amount of demineralisation around brackets measured
Time frame: From date of bracket placement to 6 months of treatment
Plan to share: No — Patient privacy
Start is estimated for Jan 2027; primary completion for Jan 2028, 12 months later.
Of 50 non-industry interventional studies with no phase under Crowding, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 28. This study's planned 12 months is below that.
Counting every sponsor, half of 52 studies reached it within 17 months; a quarter within 11 and three quarters within 28.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Foundation University Islamabad →