An interventional study of Low Fresh Gas Flow (0.5 L/min) and High Fresh Gas Flow (4 L/min) in Postoperative Atelectasis and Pulmonary Atelectasis, sponsored by Adiyaman University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-08-07.
Sponsored by Adiyaman University · Not applicable, Interventional, and Treatment
Among 53 studies in Pulmonary Atelectasis with a site in Turkey — 13 open to participants now, 16 under way, none of them phase 3. Pulmonary Atelectasis · Turkey.
Among the 53 studies in Pulmonary Atelectasis with a site in Turkey, this one is the 2nd largest by planned enrollment of the 29 interventional ones that give a count, is one of 13 that started in 2026, is one of 29 with no phase, reaches primary completion later than 10 of the 15 other live ones, and was the 51st registered.
377 studies on the registry are indexed under Pulmonary Atelectasis; 93 are open to participants now.
Browse Pulmonary Atelectasis studies →13 of the 53 studies in Pulmonary Atelectasis with a site in Turkey are open now. Recruiting first, the newest first:
Ankara University · Sites in Turkey
Ondokuz Mayıs University · Sites in Turkey
Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Sites in Turkey
Ankara Ataturk Sanatorium Training and Research Hospital · Sites in Turkey
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Sites in Turkey
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 50 Pulmonary Atelectasis studies recruiting now, 20 (40%) set no upper age limit and 22 (44%) stop at 75 or younger; 23 take children under 18; 2 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
53 studies; the count open now beside each. This study's row is marked.
First in 2011; this study’s year is marked. 13 started in 2026.
This study's planned enrollment of 120 is above the median of 60 across 268 interventional studies indexed under Pulmonary Atelectasis.
Median enrollment 60 across the 29 interventional studies, 75 across the 24 observational. Of the 33 that completed or were terminated, 3 (9%) have results posted.
This tab as a report to print or save as PDF → With an account.
None of the 53 has an industry lead sponsor. The 10 most frequent:
Adiyaman University is the lead sponsor of 31 studies on the registry; 11 are open to participants now.
Adiyaman University has 1 study filed under Pulmonary Atelectasis — fewer than ten, so there is no comparison to draw.
4 of the studies in Pulmonary Atelectasis with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07602543Ankara Etlik City HospitalLung Ultrasound Evaluation of Individualized Versus Standard PEEP on Postoperative Atelectasis in Gynecological Laparoscopy | 2026-12-30 |
| NCT07432477Ondokuz Mayıs UniversitySingle-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass | 2027-02-01 |
| NCT07654153Cumhuriyet UniversitySurgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study | 2027-06-20 |
| NCT07775573Fatih Sultan Mehmet Training and Research HospitalIndividualized vs Standard PEEP and Oxygen Reserve Index in Laparoscopic Hernia Surgery | 2027-09 |
Among the 53 studies in Pulmonary Atelectasis with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This prospective randomized clinical trial aims to evaluate the effects of different fresh gas flow rates on postoperative pulmonary aeration using lung ultrasonography in patients undergoing elective laparoscopic cholecystectomy. Patients will be randomly assigned to receive either low-flow anesthesia (0.5 L/min) or high-flow anesthesia (4 L/min) during maintenance of general anesthesia. The primary objective is to compare postoperative lung ultrasound scores and the incidence of atelectasis between the two groups.
Pulmonary atelectasis is one of the most common postoperative pulmonary complications following general anesthesia. Fresh gas flow is an important component of inhalational anesthesia and may influence airway humidity, gas exchange, respiratory mechanics, and pulmonary physiology. Although low-flow anesthesia has recognized economic, environmental, and physiological advantages, the effect of different fresh gas flow rates on postoperative lung aeration has not been adequately investigated.
This prospective, randomized, parallel-group clinical trial will be conducted at Adıyaman University Training and Research Hospital. Adult patients scheduled for elective laparoscopic cholecystectomy under general anesthesia will be randomly allocated to either a low-flow group (0.5 L/min) or a high-flow group (4 L/min) after an initial fresh gas flow of 4 L/min for 8 minutes following endotracheal intubation. Standardized anesthesia management will be applied to all participants.
Postoperative lung ultrasonography will be performed 30 minutes after extubation in the post-anesthesia care unit. Lung Ultrasound Score (LUS) and the incidence of postoperative atelectasis will be compared between the study groups. The findings are expected to provide evidence regarding the effects of different fresh gas flow strategies on postoperative pulmonary outcomes and may contribute to optimizing intraoperative anesthesia management.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will receive general anesthesia with a fresh gas flow rate of 0.5 L/min during the maintenance phase following an initial fresh gas flow of 4 L/min for 8 minutes after endotracheal intubation. Postoperative lung ultrasonography will be performed 30 minutes after extubation.
Procedure: Low Fresh Gas Flow (0.5 L/min)
Participants will receive general anesthesia with a fresh gas flow rate of 4 L/min during the maintenance phase following an initial fresh gas flow of 4 L/min for 8 minutes after endotracheal intubation. Postoperative lung ultrasonography will be performed 30 minutes after extubation.
Procedure: High Fresh Gas Flow (4 L/min)
General anesthesia will be maintained using a fresh gas flow rate of 0.5 L/min after an initial fresh gas flow of 4 L/min for 8 minutes following endotracheal intubation.
General anesthesia will be maintained using a fresh gas flow rate of 4 L/min after an initial fresh gas flow of 4 L/min for 8 minutes following endotracheal intubation.
Postoperative Lung Ultrasound Score
Lung ultrasonography will be performed 30 minutes after extubation. Both lungs will be divided into 12 regions, with 6 regions assessed in each lung. Each region will be scored from 0 to 3: 0 indicates normal aeration with A-lines or fewer than three B-lines; 1 indicates at least three well-spaced B-lines; 2 indicates coalescent B-lines; and 3 indicates lung consolidation. The scores from all regions will be summed, resulting in a total score ranging from 0 to 36. Higher scores indicate greater loss of lung aeration.
Time frame: 30 minutes after extubation
Incidence of postoperative atelectasis
Atelectasis will be defined as a consolidation score ≥2 in any lung region assessed by lung ultrasonography
Time frame: 30 minutes after extubation
Peripheral oxygen saturation (SpO₂)
Time frame: During surgery
Mean arterial pressure
Time frame: During surgery
Heart rate
Time frame: During surgery
Peak airway pressure
Peak airway pressure will be recorded during general anesthesia and compared between the low and high fresh gas flow groups.
Time frame: Throughout the intraoperative period
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Aug 2026; primary completion for Oct 2026, 2 months later.
Of 152 non-industry interventional studies with no phase under Pulmonary Atelectasis, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 24. This study's planned 2 months is below that.
Counting every sponsor, half of 154 studies reached it within 12 months; a quarter within 5 and three quarters within 24.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Adiyaman University