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Not yet recruitingNCT07712276TeleFrailtyUpdated Jul 22, 2026

The Effect of Teleconsultation, on the Reversibility of Frailty in Geriatric Patients Post Hospitalization

An interventional study of structured teleconsultation and face to face consultation and face to face consultation in Prefrail Elderly and Frail Elderly, sponsored by Indonesia University. Not yet recruiting at 1 site in Indonesia. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-07-22.

Sponsored by Indonesia University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
116
Allocation
Randomized
Ages
60 Years and older
Sex
All
01

Study summary

The goal of this clinical trial is to learn if a structured tele-consultation program, delivered 3 times over 12 weeks, can improve (reverse) frailty in geriatric patients recently discharged from the hospital. The main questions it aims to answer are:

  • Does structured tele-consultation covering physical exercise, nutrition, and home care education change health behavior in older adults after hospital discharge?
  • Does this change in health behavior lead to improvement in frailty, as measured by Clinical Frailty Scale (CFS) score?
  • Does this change in health behavior lead to improvement in frailty, as measured by decreased interleukin-6 (IL-6) and myostatin levels and increased albumin levels?
  • Does this change in health behavior lead to improvement in frailty, as measured by increased hand grip strength?

Researchers will compare participants receiving structured tele-consultation (delivered 3 times over 12 weeks) to participants receiving usual care to see if tele-consultation leads to greater improvement in health behavior and frailty status.

Participants will:

  • Undergo baseline assessment of CFS score, hand grip strength, and blood sampling for IL-6, albumin, and myostatin shortly after hospital discharge
  • Be randomly assigned to receive either structured tele-consultation (3 sessions over 12 weeks, covering physical exercise, nutrition, and home care education) or usual care
  • Undergo repeat assessment of health behavior, CFS score, hand grip strength, and the same blood markers at the end of the 12-week period
Read the detailed description

Frailty is common among older adults following hospitalization and is associated with increased risk of readmission, functional decline, and mortality. Telemedicine has been proposed to support frailty management, but prior studies have used varied formats and shown inconsistent results, and no prior study has evaluated structured tele-consultation targeting physical exercise, nutrition, and home care education as a means of reversing frailty in older adults after hospital discharge, using both a validated frailty score and biological markers as outcomes.

This study is a randomized controlled trial conducted among older adults admitted to the acute geriatric ward who are deemed fit for discharge. Eligible patients are enrolled after providing informed consent, and baseline data (frailty scores, biological markers, hand grip strength) are collected prior to discharge. Participants are randomly allocated to an intervention group or a control group. Both groups receive standard discharge planning and follow-up at the geriatric outpatient clinic over a 12-week period after discharge. In addition to standard follow-up, participants in the intervention group receive structured tele-consultation sessions addressing physical exercise, nutrition, and home care education, delivered by a trained physician, dietitian, and physiotherapist. Outcome assessments are performed at baseline and at the end of the follow-up period by an assessor unaware of participants' group allocation.

Participants who are readmitted to hospital during the study period are withdrawn from the study. All collected data are kept confidential and used only for research purposes. Data from participants who withdraw or are lost to follow-up are retained and analyzed using an intention-to-treat approach.

02

Conditions studied

  • Prefrail Elderly
  • Frail Elderly

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Keywords

  • frailty
  • prefrail
  • teleconsultation
  • elderly
  • reversibility frailty
03

Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age 60 years or older
  • Approved for hospital discharge
  • Diagnosed with pre-frailty or frailty
  • Access to a mobile phone, tablet, or laptop

Exclusion criteria

Exclusion Criteria:

  • Unwilling to participate in the study
  • Depression, as indicated by a Geriatric Depression Scale (GDS) score ≥10, assessed at the time of discharge
  • Moderate to severe cognitive impairment, as indicated by a Montreal Cognitive Assessment-Indonesian version (MoCA-INA) score \<26, assessed at the time of discharge
  • Severe frailty, as indicated by a Clinical Frailty Scale (CFS) score >8
  • Liver cirrhosis
  • Chronic kidney disease stage 4 or higher
  • Stage 4 malignancy
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
116 participants (estimated)

Study arms

  • Experimental
    Teleconsultation group

    Participants received standard discharge planning and standard face-to-face outpatient visits (consultation) at weeks 1, 5, 9, 13 post-discharge, plus structured teleconsultation (via Zoom, up to 60 minutes) conducted by a trained general practitioner, dietitian, and physiotherapist at weeks 3, 7, 11, post-discharge.

    Behavioral: structured teleconsultation and face to face consultation

  • Active comparator
    face to face consultation group

    Participants received standard discharge planning and standard face-to-face outpatient visits (consultation) only, at weeks 1, 5, 9, 13 post-discharge, without additional teleconsultation.

    Behavioral: face to face consultation

Interventions

  • Behavioralstructured teleconsultation and face to face consultation

    A structured teleconsultation delivered via videoconference (Zoom), up to 60 minutes per session, provided by a trained general practitioner, dietitian, and physiotherapist. Sessions were conducted with the patient and a consistent family member/caregiver at weeks 3, 7, 11 post-discharge, in addition to standard discharge planning and routine face-to-face outpatient visits at weeks 1, 5, 9, 13.

  • Behavioralface to face consultation

    Routine face-to-face outpatient visits to the geriatric clinic at weeks 1, 5, 9, 13, post-discharge, without additional telehealth consultation.

05

What researchers measure

Primary outcomes

  1. Change in Clinical Frailty Scale (CFS) Score

    Frailty reversibility assessed as the change in Clinical Frailty Scale (CFS) score from baseline (pre-intervention, at hospital discharge) to post-intervention, following structured telehealth consultation based on physical exercise, nutrition, and home care education aimed at health behavior change. The Clinical Frailty Scale is a 9-point clinical assessment tool used to evaluate frailty status in older adults. Scores range from 1 to 9, where 1 indicates very fit, 2 indicates Fit, 3 indicates Managing Well, 4 indicates Living with Very Mild Frailty, 5 indicates Living with Mild Frailty, 6 indicates Living with Moderate Frailty, 7 indicates Living with Severe Frailty, 8 indicates Living with Very Severe Frailty, and 9 indicates terminally ill. Higher scores indicate greater frailty and therefore a worse clinical outcome.

    Time frame: Baseline (at hospital discharge) and Week 13 post-discharge

Secondary outcomes

  1. Change in Health Behavior

    Change in health-related behaviors (physical exercise, nutrition, and medication adherence) following structured teleconsultation, assessed using a study-specific Health Behavior Questionnaire. The questionnaire consists of 5 items, each scored on a 5-point Likert scale (1-5), with a total score ranging from 5 to 25. Higher scores indicate better health-related health behaviors.

    Time frame: Baseline and Week 13 post-discharge

  2. Change in Serum Albumin Level

    Change in serum albumin level as a nutritional biomarker associated with frailty reversibility, following structured telehealth consultation.

    Time frame: Baseline and Week 13 post-discharge

  3. Change in Serum Myostatin Level

    Change in serum myostatin level as a biomarker of muscle wasting associated with frailty reversibility, following structured telehealth consultation.

    Time frame: Baseline and Week 13 post-discharge

  4. Change in Hand Grip Strength

    Change in hand grip strength, measured using a dynamometer, as an indicator of physical frailty component, following structured telehealth consultation.

    Time frame: Baseline and Week 13 post-discharge

  5. Change in IL-6

    Change in IL-6 following structured telehealth consultation.

    Time frame: Baseline and Week 13 post-discharge

06

Study locations

1 site
  • Cipto Mangunkusumo Hospital
    Jakarta, Central Jakarta 10430, Indonesia
    • Arya Govinda Roosheroe, MD · Contact · argov0504@gmail.com · +62 812-9430-3863
    • Arya Govinda Roosheroe, MD · Principal investigator
    • Siti Setiati, Prof, MD, PhD · Sub investigator
    • Kuntjoro Harimurti, MD, PhD · Sub investigator
    • Edy Rizal Wachyudi, MD, PhD · Sub investigator
    • IGP Suka Aryana, MD, PhD · Sub investigator
    • Nurul Ratna Mutu Manikam, MD, PhD · Sub investigator
    • Melinda Harini, MD, PhD · Sub investigator
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07712276
Lead sponsor
Indonesia University
Responsible party
Arya Govinda Roosheroe (MD, Indonesia University) — Principal investigator
First posted
Jul 17, 2026
Start date
Aug 3, 2026 (estimated)
Primary completion
Jun 30, 2027 (estimated)
Completion
Aug 31, 2027 (estimated)
Last update
Jul 22, 2026

Study contacts

Arya Govinda Roosheroe, MD
Contact
argov0504@gmail.com
+62 812-9430-3863

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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