An interventional study of concentric group and eccentric group in Exercise, sponsored by Karabuk University. Enrolling by invitation at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-17.
Sponsored by Karabuk University · Not applicable, Interventional, and Other
Among 995 studies in Motor Activity with a site in Turkey — 196 open to participants now, 225 under way, none of them phase 3. Motor Activity · Turkey.
Among the 995 studies in Motor Activity with a site in Turkey, this one is the 522nd largest by planned enrollment of the 768 interventional ones, is one of 101 that started in 2026, is one of 768 with no phase, reaches primary completion later than 154 of the 224 other live ones, and was the 945th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
This study's planned enrollment of 34 is below the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →196 of the 995 studies in Motor Activity with a site in Turkey are open now, in 1 country. Each count lists the studies.
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 35 Years · all sexes · healthy volunteers too.
The full table on the hub →995 studies; the count open now beside each. This study's row is marked.
First in 2002; this study’s year is marked. 101 started in 2026.
Median enrollment 42 across the 768 interventional studies, 70 across the 227 observational. Of the 697 that completed or were terminated, 5 (1%) have results posted.
1 of 995 have an industry lead sponsor. The 10 most frequent:
Karabuk University is the lead sponsor of 143 studies on the registry; 40 are open to participants now.
Karabuk University has 9 studies filed under Motor Activity — fewer than ten, so there is no comparison to draw.
51 of the studies in Motor Activity with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06989138Medipol UniversityEffects of Orthosis & Exercise on Spondylolisthesis | 2026-11 |
| NCT06754475Tarsus UniversityEffects of Upper Extremity Low Volume HIIT in Heart Failure | 2026-11-01 |
| NCT07794904Istanbul UniversityEffectiveness of a Tele-Rehabilitation-Based Exercise and Self-Lymphatic Drainage Program Supported by Self-Management for Breast Cancer-Related Lymphedema | 2026-11-02 |
| NCT07873567Mardin Artuklu UniversityMusculoskeletal Discomfort and Ergonomic Factors in Midwifery Students | 2026-11-05 |
| NCT07681427Hacettepe UniversityEffects of a 12-week T10 Exercise Program on Shooting Performance, Upper Extremity Function, Balance and Reaction Time in Competitive Air Pistol Athletes | 2026-11-15 |
Among the 995 studies in Motor Activity with a site in Turkey, from their registry updates:
This randomized controlled trial will investigate the effects of blood flow restriction (BFR) training combined with concentric or eccentric exercise on upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy adults aged 18-35 years. A total of 34 participants will be randomly allocated to either a BFR combined with concentric exercise group (n=17) or a BFR combined with eccentric exercise group (n=17).
Before the intervention, maximal muscle strength will be determined using a one-repetition maximum (1RM) test for the dominant elbow flexor muscles. Upper extremity reaction speed will be assessed using the Nelson Hand Reaction Test. Biceps brachii muscle strength will be measured with a digital dynamometer, and muscle oxygenation will be evaluated using a near-infrared spectroscopy (NIRS) device. All outcome measures will be obtained 72 hours before the intervention and repeated 72 hours after completion of the training program by the same investigator.
The findings of this study will contribute to understanding whether concentric or eccentric exercise combined with BFR training provides greater improvements in upper extremity reaction speed, muscle strength, and muscle oxygenation in healthy individuals.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: concentric group · Other: eccentric group
Other: concentric group · Other: eccentric group
Participants assigned to this group will perform blood flow restriction (BFR) training combined with concentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Participants assigned to this group will perform blood flow restriction (BFR) training combined with eccentric elbow flexion exercises using the dominant upper extremity. Training will be performed three times per week for four weeks (12 sessions). Exercises will be performed at 20-30% of one-repetition maximum (1RM) using a pneumatic cuff applied to the proximal upper arm. The cuff pressure will be set at 50% of the individual's arterial occlusion pressure. Each session will consist of four sets (30-15-15-15 repetitions) with 30-second rest intervals between sets.
Upper Extremity Reaction Time
Upper extremity reaction time will be assessed using the Nelson Hand Reaction Test. Participants will complete five trials, the highest and lowest values will be discarded, and the mean of the remaining three trials will be used for analysis. Reaction time will be calculated from the ruler drop distance using the standard equation.
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Biceps Brachii Muscle Strength
Biceps brachii muscle strength will be measured using an ActivForce 2 digital dynamometer. Three maximal isometric contractions will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Hand Grip Strength
Hand grip strength will be measured using a hydraulic hand dynamometer. Participants will perform three maximal contractions with 30-second rest intervals, and the highest value will be recorded for analysis.
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Pinch Strength
Pinch strength will be assessed using a pinch dynamometer. Three maximal trials will be performed with 30-second rest intervals, and the highest value will be used for analysis.
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
One-Repetition Maximum
Maximum muscle strength of the elbow flexors will be estimated using the Epley equation based on the maximum number of repetitions completed with a fixed load (2 kg for females and 5 kg for males).
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Muscle Oxygen Saturation
Muscle oxygen saturation (SmO₂) of the biceps brachii will be measured using a MOXY near-infrared spectroscopy (NIRS) device. Baseline SmO₂ will be recorded before the 1RM test, continuous SmO₂ values will be monitored throughout the test, and recovery values will be recorded for 2-3 minutes after the test.
Time frame: Baseline (72 hours before the intervention) and 72 hours after completion of the 4-week intervention.
Plan to share: No
Start is estimated for Aug 2026; primary completion for Oct 2026, 2 months later.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's planned 2 months is below that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
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