An observational study in Gingival Recession, Mucogingival Surgery and Keratinized Tissue Deficiency, sponsored by Bezmialem Vakif University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-07-16.
Sponsored by Bezmialem Vakif University · Observational
The purpose of this retrospective clinical study is to compare the long-term aesthetic integration and clinical outcomes of two periodontal plastic surgery techniques: Gingival Unit Grafting (GUG) and Free Gingival Grafting (FGG). The study evaluates the effectiveness of these procedures in increasing keratinized tissue width and assesses the color integration of the grafted tissues with the surrounding gingiva over an 18-month follow-up period using objective digital color analysis based on CIE Lab and RGB parameters.
This single-center retrospective study included patients treated with either Gingival Unit Grafts (GUG) or Free Gingival Grafts (FGG) for the management of Cairo Type 2 and Type 3 gingival recessions between March 2022 and December 2022. Clinical and photographic records obtained at baseline and during follow-up visits up to 18 months were retrospectively analyzed. The primary outcome was the evaluation of color integration of the grafted tissues using objective digital color analysis based on CIE Lab and RGB parameters. Secondary outcomes included changes in keratinized tissue width. The aim of the study was to compare the long-term aesthetic integration and clinical performance of GUG and FGG and to determine which technique provides superior color matching with the surrounding tissues.
402 studies on the registry are indexed under Gingival Recession; 98 are open to participants now.
This study's enrollment of 40 is close to the median of 44 across 29 observational studies indexed under Gingival Recession.
Browse Gingival Recession studies →Bezmialem Vakif University is the lead sponsor of 345 studies on the registry; 58 are open to participants now.
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The study population consists of adult patients seeking treatment for localized gingival recessions on mandibular incisors at a university faculty of dentistry.
Exclusion Criteria:
Patients who underwent periodontal plastic surgery using Gingival Unit Grafts for keratinized tissue gain
Procedure: Gingival Unit Grafting
Patients who underwent periodontal plastic surgery using Conventional Free Gingival Grafts for keratinized tissue gain
Procedure: Conventional Free Gingival Grafting
Harvesting a gingival unit graft and transplanting it to the recipient area to increase keratinized tissue width and assess long-term aesthetic integration.
Harvesting a conventional free gingival graft and transplanting it to the recipient area to increase keratinized tissue width and serve as a control group for aesthetic integration.
Aesthetic Integration (Color Evaluation)
Objective assessment of color integration between the grafted tissue and the surrounding gingiva using digital color analysis. Color parameters were evaluated based on the CIE Lab\* color space system and RGB color channels obtained from standardized clinical photographs. The degree of color matching between grafted and adjacent tissues was assessed over the follow-up period.
Time frame: Baseline and 18 months post-surgery
Keratinized Tissue Width (KTW)
The clinical measurement of the width of keratinized tissue in millimeters, evaluated from the gingival margin to the mucogingival junction using a standard periodontal probe to determine the amount of tissue gain.
Time frame: Baseline and 18 months post-surgery
Plan to share: No
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This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Bezmialem Vakif University