An observational study in Periodontal Diseases, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-08.
Sponsored by Al-Azhar University · Observational
This study aims to develop and validate an artificial intelligence-based system for automated measurement of keratinized gingiva width using smartphone-acquired intraoral clinical photographs. Standardized intraoral images will be collected and analyzed using a deep learning model, and the results will be compared with clinical measurements performed by calibrated expert examiners, which serve as the reference standard. The performance of the proposed system will be evaluated using accuracy metrics including Dice coefficient, Intersection over Union (IoU), precision, recall, and F1-score. This study seeks to support the integration of AI tools into periodontal diagnosis and clinical decision-making to improve measurement consistency and reduce inter-examiner variability.
This observational diagnostic validation study was conducted to develop and evaluate an artificial intelligence-based system for automated assessment of keratinized gingiva width (KGW) using smartphone-acquired intraoral clinical photographs.
Standardized intraoral images were collected from eligible participants following predefined inclusion and exclusion criteria. All images were captured using a smartphone under standardized clinical conditions to ensure uniformity in lighting, angulation, and image quality. Clinical measurements of keratinized gingiva width were independently performed by two calibrated expert examiners, serving as the reference (ground truth) standard.
A deep learning-based model was trained to segment and measure the keratinized gingival tissue from clinical images. The predicted measurements generated by the AI system were compared against the expert clinical measurements to evaluate model performance.
The performance of the system was assessed using multiple evaluation metrics, including accuracy, Dice similarity coefficient, Intersection over Union (IoU), precision, recall, and F1-score. Inter-examiner reliability between experts was also considered to ensure consistency of the reference standard.
The study aims to demonstrate the feasibility of integrating artificial intelligence into periodontal diagnostics, specifically for objective and reproducible measurement of keratinized gingiva width. The proposed system may contribute to reducing inter-operator variability and improving clinical efficiency in periodontal assessment.
830 studies on the registry are indexed under Periodontal Diseases; 189 are open to participants now.
This study's enrollment of 50 is below the median of 100 across 291 observational studies indexed under Periodontal Diseases.
Browse Periodontal Diseases studies →Al-Azhar University is the lead sponsor of 505 studies on the registry; 167 are open to participants now.
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Participants attending the clinic of the department of Periodontologly Faculty of Dental Medicine for girls Al-Azhar university who met the study eligibility criteria and provided smartphone-acquired intraoral clinical photographs for keratinized gingiva width assessment and artificial intelligence model validation.
Patients with varying periodontal conditions thealthy. gingivitis, periodontitie.
Patients willing to provide adormed consent.
Exclusion Criteria:
Patients withsystemic conditions affecting oraltissue eg. diabetes.
Very poor quality intra oral image.
Participants whose smartphone-acquired intraoral clinical photographs were used for assessment of keratinized gingiva width. Clinical measurements performed by expert examiners served as the reference standard for validation of the artificial intelligence model.
Diagnostic Test: Artificial Intelligence-Based Keratinized Gingiva Width Assessment
Analysis of smartphone-acquired intraoral photographs using a deep learning model for automated measurement of keratinized gingiva width.
Accuracy of Artificial Intelligence-Based Keratinized Gingiva Width Measurement
Evaluation of the agreement between keratinized gingiva width measurements generated by the artificial intelligence model and reference measurements obtained by calibrated examiners using smartphone-acquired intraoral clinical photographs at the baseline clinical visit.
Time frame: Baseline (single study visit)
Plan to share: No — IPD will not be shared to protect patient confidentiality and in compliance with institutional ethical guidelines. Data access is limited to the study investigators only.
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Al-Azhar University