ClinicalTrials.gg
Enrolling by invitationNCT07662993Updated Jun 23, 2026

Factors Associated With Cognitive Skills in Patients With Fibromyalgia

An observational study in Fibromyalgia and Cognition, sponsored by Zülal TATAR. Enrolling by invitation at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-23.

Sponsored by Zülal TATAR · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
41
Ages
18 Years to 65 Years
Sex
Female
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Where this study stands

Counted across the records on this site · 2026-11-12

Among 195 studies in Fibromyalgia with a site in Turkey — 51 open to participants now, 55 under way, none of them phase 3. Fibromyalgia · Turkey.

Planned enrollment
83rd of 91
41 · median 100
Started
2026
with 24 others
Observational
91 of 195
25 open now
Primary completion
2027-08
later than 49 of 54 live
Registered
181st of 195
by date

Among the 195 studies in Fibromyalgia with a site in Turkey, this one is the 83rd largest by planned enrollment of the 91 observational ones that give a count, is one of 25 that started in 2026, is one of 91 observational ones, reaches primary completion later than 49 of the 54 other live ones, and was the 181st registered.

Fibromyalgia

1,243 studies on the registry are indexed under Fibromyalgia; 256 are open to participants now.

Browse Fibromyalgia studies →

Open to participants now

51 of the 195 studies in Fibromyalgia with a site in Turkey are open now. Recruiting first, the newest first:

46 more — sign in →

All 51 open studies →

A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →

Who these studies take

Of the 160 Fibromyalgia studies recruiting now, 50 (31%) set no upper age limit and 96 (60%) stop at 75 or younger; 14 take children under 18; 35 take healthy volunteers.

This study: 18 Years to 65 Years · female.

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Study summary

The aim of this study was to identify factors associated with cognitive skills in female patients with fibromyalgia.

03

Conditions studied

  • Fibromyalgia
  • Cognition

Browse trials for

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
Female
Sampling method
Probability sample

Study population

At least 41 female fibromyalgia patients aged 18-65 years who are followed by Pamukkale University Rheumatology Clinic, diagnosed according to the 2011 American Rheumatology Association Fibromyalgia classification criteria, and who meet the inclusion criteria will be included in the study.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Being between 18-65 years of age
  • Being female
  • Having been diagnosed with fibromyalgia for at least 6 months, with the appearance of a range of somatic and cognitive symptoms in addition to widespread pain.

Exclusion criteria

Exclusion Criteria:

  • Having another illness that affects their physical condition
  • Having cognitive impairment to the extent that they cannot cooperate
  • Being pregnant
  • Impaired Turkish language comprehension or speech
  • Concurrent or inflammatory disease
  • Diseases affecting the central nervous system (e.g., multiple sclerosis, Parkinson's disease)
  • Serious psychiatric conditions that prevent participation (e.g., psychotic disorders).
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Autoimmune disease

A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.

Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.

05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
41 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. Dynamic Loewenstein Occupational Therapy Cognitive Assessment (DLOTCA)

    DLOTCA assesses the basic cognitive skills of individuals aged 18-69 years using 28 subtests across 7 cognitive domains (Awareness, Orientation, Spatial Perception, Visual Perception, Visual-Motor Structuring, Application, and Thinking Processes) (13). Each subtest has 3 scoring stages: First stage: Pre-mediation scoring (1 point indicates the worst performance). Second stage: Mediation score (a high score (4 or 5) indicates poor performance). Third stage: Post-mediation scoring (1 point indicates the worst performance).

    Time frame: At baseline (Day 1)

Secondary outcomes

  1. Fibromyalgia Impact Questionnaire

    This physical impact scale, administered to patients, was developed by Burchardt et al. to measure functional status in fibromyalgia patients. The scale primarily measures 10 separate characteristics: physical function, well-being, inability to work, difficulty at work, pain, fatigue, morning fatigue, stiffness, anxiety, and depression. Except for well-being, lower scores indicate improvement or less severe impact from the disease. Each subcategory can have a maximum score of 10, resulting in a total maximum score of 100.

    Time frame: At Baseline (Day 1)

  2. Pressure Pain Threshold Measurements

    Pressure pain threshold measurements will be assessed using a pressure algometer, a gun-shaped apparatus with a 1-cm² rigid rubber probe held at a 90-degree angle to the body and then applying pressure at a constant rate of increasing pressure (30 kPa/s) until the patient's pain threshold is reached. The assessment will be performed bilaterally in 4 different regions, one assessment per anatomical region: trapezius muscle, elbows (lateral epicondyle), quadriceps femoris muscle, and knees (in the medial fat pad near the joint line). For each participant, the total mean pressure pain threshold measurements will be calculated and used for analysis. Sensitive points will be determined according to the guidelines of Okifuji et al. Previous studies have shown that assessing pressure pain threshold measurements in a limited number of regions provides a good estimate of overall sensitivity.

    Time frame: At baseline (Day 1)

  3. Cognitive Exercise Therapy Approach Scale

    The Cognitive Exercise Therapy Approach Scale assesses the biopsychosocial status of patients with rheumatic diseases. The total score ranges from 0 to 120. Higher scores indicate a worse biopsychosocial status.

    Time frame: At baseline (Day 1)

  4. Tampa Kinesiophobia Scale

    The original Tampa Kinesiophobia Scale was developed by Miller, Kopri and Todd in 1991, but was not published. Vlaeyen et al. republished the original scale, consisting of 17 questions, in 1995, with the permission of the researchers who developed it. TAS is a 17-question scale developed to measure fear of movement/re-injury. The scale includes injury/re-injury and fear-avoidance parameters in work-related activities.

    Time frame: At Baseline (Day 1)

  5. Pain Catastrophizing Scale:

    Developed to identify patients' catastrophic thoughts or feelings about the pain they experience and their ineffective coping strategies, this scale is a thirteen-item Likert-type self-assessment scale. Each item is scored between 0 and 4. The total score ranges from 0 to 52. Higher scores indicate a high level of catastrophizing.

    Time frame: At baseline (Day 1)

  6. The Short Pain Inventory

    The Short Pain Inventory is a short, easy-to-administer assessment method that can be used to evaluate pain. It includes numerical rating scales from 0 to 10. In the Short Pain Inventory, the worst pain is defined as mild (1-4), moderate (5-6), and severe (7-10). It assesses the severity of pain, its localization, medical treatments for pain, and its impact on daily functions, and asks how much pain has decreased in the last 24 hours or the past week. Answering all questions takes a short time, approximately 5-10 minutes.

    Time frame: At baseline (Day 1)

  7. Generalized Pain Index and Symptom Severity Scale

    The Generalized Pain Index is an index that assesses a patient's pain in 19 regions over the past week. The Symptom Severity Scale consists of 3 questions: fatigue, difficulty thinking and remembering, and sleeplessness. The severity of each of these 3 complaints over the past week is scored using a scale from 0: no problem, 1: mild problem, 2: moderate problem, 3: severe problem.

    Time frame: At baseline (Day 1)

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Study locations

1 site
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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started May 2026 (actual). Primary completion is estimated for Aug 2027, 15 months after the start.

Of 81 non-industry observational studies under Fibromyalgia, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 109. This study's planned 15 months is below that.

Counting every sponsor, half of 88 studies reached it within 27 months; a quarter within 8 and three quarters within 91.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 17, 2026
First posted
Jun 23, 2026
StartActual
May 12, 2026
Primary completionEst.
Aug 12, 2027
CompletionEst.
Sep 12, 2027
Last update
Jun 23, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07662993
Lead sponsor
Zülal TATAR
Responsible party
Zülal TATAR (Lecturer, Pamukkale University) — Sponsor-investigator
First posted
Jun 23, 2026
Start date
May 12, 2026
Primary completion
Aug 12, 2027 (estimated)
Completion
Sep 12, 2027 (estimated)
Last update
Jun 23, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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