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CompletedNCT07622745Updated Jun 3, 2026

Nasal Surgery in Snoring and Obstructive Sleep Apnea

An interventional study of Septoplasty with partial inferior turbinectomy and Nasal polypectomy in Nasal Surgery, Snoring and Obstructive Sleep Apnea, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-03.

Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 4 years 2 months after the study started (first participant enrolled Mar 2022, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.

Read the detailed description

Snoring is the noisy breathing that occurs throughout sleep, resulting from the vibration of the structures in the oral cavity, including the soft palate, uvula, tonsils, base of the tongue, epiglottis, as well as pharyngeal walls.

Obstructive sleep apnea syndrome (OSAS) is a respiratory sleep disorder distinguished by repeated episodes of partial or total occlusion of the upper airways throughout sleep. This blockage is typically associated with a decrease (hypopnea) or total cessation (apnea) of airflow in the upper airways, and sustained thoracic-diaphragmatic respiratory movements.

02

Conditions studied

  • Nasal Surgery
  • Snoring
  • Obstructive Sleep Apnea
03

In context

Snoring

122 studies on the registry are indexed under Snoring; 15 are open to participants now.

This study's enrollment of 30 is below the median of 43 across 95 interventional studies indexed under Snoring.

Browse Snoring studies →

Lead sponsor

Al-Azhar University is the lead sponsor of 531 studies on the registry; 172 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age above 18 years.
  • Both sexes.
  • Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps to medical treatment.
  • Presence of snoring and obstructive sleep apnea (OSA).
  • Fitness for surgery.

Exclusion criteria

Exclusion Criteria:

  • Central or mixed sleep apnea.
  • Previous nasal surgery.
  • Unfitness for surgery.
  • Pathological obesity.
  • History of cardiopulmonary disease or asthma.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Relapsed and refractory

Relapsed: the illness came back after treatment had worked. Refractory: it did not respond to treatment, or stopped responding while still on it.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Group I

    Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.

    Procedure: Septoplasty with partial inferior turbinectomy

  • Experimental
    Group II

    Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.

    Procedure: Nasal polypectomy

  • Experimental
    Group III

    Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

    Procedure: Partial inferior turbinectomy

Interventions

  • ProcedureSeptoplasty with partial inferior turbinectomy

    Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.

  • ProcedureNasal polypectomy

    Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.

  • ProcedurePartial inferior turbinectomy

    Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

06

What researchers measure

Primary outcomes

  1. Apnea-Hypopnea Index

    The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.

    Time frame: 3 months postoperatively

Secondary outcomes

  1. Snoring index

    The snoring index was defined as the number of snoring episodes divided by the hours of total sleep time

    Time frame: 3 months postoperatively

07

Study locations

1 site
  • Al-Azhar University
    Cairo, 11651, Egypt
08

References and documents

Individual participant data

Plan to share: Yes — The data will be available upon a reasonable request from the corresponding author after the end of study for one year.

Supporting information: Study protocol

Time frame: After the end of study for one year.

Access criteria: The data will be available upon a reasonable request from the corresponding author.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07622745
Responsible party
Asmaa Abdullah El Muhammady Ebrahim (Resident of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University for Girls, Egypt., Al-Azhar University) — Principal investigator
First posted
Jun 3, 2026
Start date
Mar 1, 2022
Primary completion
Jul 1, 2024
Completion
Jul 1, 2024
Last update
Jun 3, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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