An interventional study of Exercise Training in Multiple Sclerosis, sponsored by The University of Texas Health Science Center, Houston. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by The University of Texas Health Science Center, Houston · Not applicable, Interventional, and Supportive care
Among 10 studies in Multiple Sclerosis by The University of Texas Health Science Center, Houston — 3 open to participants now, 3 under way, none of them phase 3. Multiple Sclerosis · The University of Texas Health Science Center, Houston.
Among the 10 studies in Multiple Sclerosis by The University of Texas Health Science Center, Houston, this one is the only one that started in 2026, is one of 6 with no phase, and was the 9th registered.
3,264 studies on the registry are indexed under Multiple Sclerosis; 659 are open to participants now.
Browse Multiple Sclerosis studies →3 of the 10 studies in Multiple Sclerosis by The University of Texas Health Science Center, Houston are open now, in 1 country. Recruiting first, the newest first:
The University of Texas Health Science Center, Houston · Sites in United States
The University of Texas Health Science Center, Houston · Sites in United States
By country, each count listing its studies:
Of the 430 Multiple Sclerosis studies recruiting now, 163 (38%) set no upper age limit and 211 (49%) stop at 75 or younger; 40 take children under 18; 96 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
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10 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 1 started in 2026.
This study's planned enrollment of 66 is above the median of 50 across 2,201 interventional studies indexed under Multiple Sclerosis.
Median enrollment 25 across the 8 interventional studies, 1,002 across the 2 observational. Of the 6 that completed or were terminated, 4 (67%) have results posted.
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The University of Texas Health Science Center, Houston is the lead sponsor of 897 studies on the registry; 214 are open to participants now.
Of its 173 completed or terminated interventional studies of FDA-regulated products, 142 (82%) have results posted.
None of the studies under way reaches primary completion within a year.
Among the 10 studies in Multiple Sclerosis by The University of Texas Health Science Center, Houston, from their registry updates:
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The purpose of this study is to establish differences in the primary outcome of walking dysfunction using the 12-Item Multiple Sclerosis Walking Scale (MSWS-12) and to establish differences in the secondary outcome of HRQoL using the 29-Item Multiple Sclerosis Walking Scale (MSWS-29) between the exercise training intervention condition and the waitlist control condition following the 16-week intervention period.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Behavioral: Exercise Training
Participants will then be mailed exercise materials in their preferred language, including the program manual, logbook, calendar, newsletters, Fitbit, and resistance bands, along with instructions for telephone or video conference calls. This is a 16-week, home-based program, supported remotely via Internet-based behavioral coaching, which integrates behavior change techniques based on Social Cognitive Theory (SCT)
Change in walking ability as assessed by the 12-Item Multiple Sclerosis Walking Scale (MSWS-12)
This is a 12 item questionnaire and each is scored on a 5-point Likert scale from 1(not at all) to 5(extremely). Total raw scores ranging from 12-60 are converted into standardized scores from 0-100, with higher scores indicating greater perceived walking impairment related to multiple sclerosis.
Time frame: Baseline, 16 weeks, 32 weeks
Change in HRQoL as assessed by the 29-Item Multiple Sclerosis Walking Scale (MSWS-29)
This is a 29 item questionnaire and each is scored from 1( not at all) to 5(extremely) , with a Raw score range from 29 to 145. This is then converted into a standardized scale from 0 to 100, with higher scores indicating worse walking impairment and greater impact of multiple sclerosis on mobility.
Time frame: Baseline, 16 weeks, 32 weeks
Started Aug 2026 (actual). Primary completion is estimated for Jun 2028, 22 months after the start.
Of 847 non-industry interventional studies with no phase under Multiple Sclerosis, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 43. This study's planned 22 months is close to that.
Counting every sponsor, half of 869 studies reached it within 21 months; a quarter within 9 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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