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CompletedNCT07605026Updated May 22, 2026

Endoscopic DCR With and Without Internal Nasal Splint

An interventional study of Endoscopic DCR with putting internal nasal splint and Endoscopic DCR without putting internal nasal splint in Synechia After DCR, sponsored by Kafrelsheikh University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-22.

Sponsored by Kafrelsheikh University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 2 years 4 months after the study started (first participant enrolled Jan 2024, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
150
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study aims to compare the outcomes of endoscopic DCR performed with versus without internal nasal splints, by assessing functional outcomes, complication rates, and overall success rates.

02

Conditions studied

  • Synechia After DCR
03

In context

Lead sponsor

Kafrelsheikh University is the lead sponsor of 285 studies on the registry; 110 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age >18 years. Symptomatic NLDO (epiphora, recurrent dacryocystitis). Fit for general anesthesia

Exclusion criteria

Exclusion Criteria:

  • Congenital dacryocystitis. Canalicular or punctal obstruction. Previous lacrimal surgery. Post-traumatic or post-radiation epiphora. Coexisting nasal pathology (tumors, granulomatous disease, atrophic rhinitis). Immunocompromised or uncontrolled systemic disease. Patients unwilling to undergo endoscopic surgery.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
150 participants (actual)

Study arms

  • Active comparator
    Endoscopic DCR with internal nasal splint

    Patients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus

    Procedure: Endoscopic DCR with putting internal nasal splint

  • Active comparator
    Endoscopic DCR without internal nasal splint.

    Patients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus

    Procedure: Endoscopic DCR without putting internal nasal splint

Interventions

  • ProcedureEndoscopic DCR with putting internal nasal splint

    Patients will undergo Endoscopic DCR with putting internal nasal splint between middle turbinate and middle meatus

  • ProcedureEndoscopic DCR without putting internal nasal splint

    Patients will undergo Endoscopic DCR without putting internal nasal splint between middle turbinate and middle meatus

06

What researchers measure

Primary outcomes

  1. Success rates as Stomal patency , absence of formation of synechia and cessation of epiphora.

    Time frame: Evaluation will be done by nasal endoscopic examination of the middle meatus after 1 month

07

Study locations

1 site
  • Kafrelsheikh University Hospitals
    Kafrelsheikh, Egypt
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07605026
Lead sponsor
Kafrelsheikh University
Responsible party
Ahmed Magdi Noaman Othman Orabi (Principal Investigator, Kafrelsheikh University) — Principal investigator
First posted
May 22, 2026
Start date
Jan 15, 2024
Primary completion
Jun 5, 2025
Completion
Jul 3, 2025
Last update
May 22, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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