ClinicalTrials.gg
Not yet recruitingNCT07600502Updated Sep 24, 2026

Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.

An interventional study of Hyperangulated videolaryngoscopy in Intubation Skill, Intubation Complications and Intubation With Uncuffed Endotracheal Tube, sponsored by NHS Lothian. Not yet recruiting at 1 site in United Kingdom. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-24.

Sponsored by NHS Lothian · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
500
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe. To see exactly where to put the tube, the anaesthetist uses a device called a laryngoscope.

A commonly used laryngoscope is the McGrath videolaryngoscope. It has a small camera and screen to help guide safe placement of the tube. It comes in two different shapes - one shaped in the same way laryngoscopes have been shaped for the last 80 years, and another newer design (McGrath X-blade) that matches the curve of patients' tongues better.

All different classes of videolaryngoscope have been shown to have benefits to patients; however, the best videolaryngoscope shape has yet to be determined.

The McGrath X-blade is currently recommended in patients in whom the anaesthetist thinks it might be slightly more difficult to place the tube, but some anaesthetists already prefer to use it in all their patients. This is not a new device or a new technique.

In this study, the investigators wish to explore if there is any special benefit of using it in all patients, by collecting some information when the device is used.

02

Conditions studied

  • Intubation Skill
  • Intubation Complications
  • Intubation With Uncuffed Endotracheal Tube

Keywords

  • videolaryngoscopy
  • hyperangulated blade
  • first-pass success
  • airway management
03

In context

Lead sponsor

NHS Lothian is the lead sponsor of 53 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adult patients undergoing surgical procedures requiring tracheal intubation as part of their routine anaesthetic care
  • Patients undergoing either naso- or oro-tracheal intubation
  • Patients undergoing tracheal intubation with or without administration of neuromuscular blocking agents (e.g. those undergoing surgery where facial nerve or recurrent laryngeal nerve monitoring will be utilised)

Exclusion criteria

Exclusion Criteria:

  • Patients \<18 years of age
  • Patients in whom tracheal intubation is not required as part of their routine anaesthetic care
  • Patients in whom tracheal intubation was not planned as part of their routine anaesthetic care, but was required as a rescue technique (e.g. for failed insertion of a supraglottic airway) since appropriate patient consent will not have been obtained · Patients that are physiologically unstable (where clinical care must take priority and/or patient is unable to consent for inclusion in the study)
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
500 participants (estimated)

Study arms

  • Experimental
    Use of McGrath X-blade to facilitate tracheal intubation

    Unselected adult patients who have been assessed as requiring tracheal intubation for their surgical intervention/ongoing care, will undergo their intubation procedure facilitated by McGrath X-blade

    Device: Hyperangulated videolaryngoscopy

Interventions

  • DeviceHyperangulated videolaryngoscopy

    Hyperangulated videolaryngoscopy using McGrath X-blade

06

What researchers measure

Primary outcomes

  1. First-pass success

    Incidence of successful tracheal intubation at the first attempt (without complications) using the McGrath-X blade

    Time frame: 5 minutes

Secondary outcomes

  1. Overall incidence of tracheal intubation success

    Overall incidence of tracheal intubation success with the McGrath-X blade without complications (maximum of 3 attempts with the device)

    Time frame: 5 minutes

  2. Incidence of complications

    Incidence of immediate airway-related complications

    Time frame: 5 minutes

07

Study locations

1 site
08

References and documents

Publications

  • Saul SA, Ward PA, McNarry AF. Airway Management: The Current Role of Videolaryngoscopy. J Pers Med. 2023 Aug 29;13(9):1327. doi: 10.3390/jpm13091327. PubMed 37763095 ↗
  • Hansel J, Rogers AM, Lewis SR, Cook TM, Smith AF. Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation: a Cochrane systematic review and meta-analysis update. Br J Anaesth. 2022 Oct;129(4):612-623. doi: 10.1016/j.bja.2022.05.027. Epub 2022 Jul 9. PubMed 35820934 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Nov 2026; primary completion for Jun 2027, 7 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 30, 2026
First posted
May 20, 2026
StartEst.
Nov 2026
Primary completionEst.
Jun 2027
CompletionEst.
Sep 2027
Last update
Sep 24, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07600502
Lead sponsor
NHS Lothian
Collaborators
Medtronic
Responsible party
Sponsor
First posted
May 20, 2026
Start date
Nov 2026 (estimated)
Primary completion
Jun 2027 (estimated)
Completion
Sep 2027 (estimated)
Last update
Sep 24, 2026

Study contacts

Patrick A Ward
Contact
patrick.ward@nhs.scot
+44(0)1506523064
Pamela Milligan
Contact
pamela.milligan@nhs.scot
+44(0)1506523064
Patrick A Ward
study director · NHS Lothian

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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