An observational study in Atrial Fibrillation and Atrial Arrhythmia, sponsored by University of Chicago. Completed at 20 sites in 9 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-12.
Sponsored by University of Chicago · Observational
The purpose of this multicenter study is to collect information from routine clinical practices for patients with left atrial appendage occlusion (LAAO) devices presenting for pulmonary vein isolation (PVI) or left atrial ablation. Assessment will include characterization of patient characteristics, procedural details, management of post-procedure anticoagulation, and clinical outcomes.
3,870 studies on the registry are indexed under Atrial Fibrillation; 924 are open to participants now.
This study's enrollment of 198 is below the median of 300 across 1,363 observational studies indexed under Atrial Fibrillation.
Browse Atrial Fibrillation studies →University of Chicago is the lead sponsor of 907 studies on the registry; 182 are open to participants now.
Of its 99 completed or terminated interventional studies of FDA-regulated products, 68 (69%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation.
Exclusion Criteria:
Individuals undergoing any type of atrial fibrillation ablation or left atrial arrhythmia ablation for routine care
Other: Data collection
Data collection on patient characteristics and comorbidities, baseline echocardiographic data, home medications including oral anticoagulation regimen, ablation data, left atrial appendage occlusion device data, and complication-related details from routine procedures and encounters
Patient characteristics
Data will be collected to characterize patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation
Time frame: Month 0, baseline
Procedural characteristics
Data will be collected to characterize pulmonary vein isolation or left atrial ablation procedural details for patients with left atrial appendage occlusion devices
Time frame: Month 0, during procedure
Post-procedure anticoagulation management
Data will be collected to characterize post-procedure anticoagulation management for patients with left atrial appendage occlusion devices
Time frame: Through 24 months
Clinical outcomes
Data will be collected to characterize clinical outcomes for patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation
Time frame: Through 24 months
Procedure-related complications
Data will be collected to characterize procedure-related complications for patients with left atrial appendage occlusion devices presenting for pulmonary vein isolation or left atrial ablation
Time frame: Through 6 months
This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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University of Chicago