An interventional study of Test interdental brush and Comparative interdental brush in Periodontal Disease, sponsored by Pierre Fabre Dermo Cosmetique. Recruiting at 1 site in Belgium. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-05-08.
Sponsored by Pierre Fabre Dermo Cosmetique (part of Pierre Fabre) · Not applicable, Interventional, and Prevention
The aim of this exploratory study is to evaluate the efficacy of the tested interdental brush versus comparative interdental brushes in adults with periodontal disease, over a 4-week period.
This study will take place at a single center as an intra-individual, split mouth, randomized, comparative study to evaluate the efficacy of the tested interdental brushes versus the comparative interdental brushes in adults with periodontal disease, over a 4-week period.
3 visits are planned:
867 studies on the registry are indexed under Periodontal Diseases; 189 are open to participants now.
This study's planned enrollment of 88 is above the median of 45 across 557 interventional studies indexed under Periodontal Diseases.
Browse Periodontal Diseases studies →Pierre Fabre Dermo Cosmetique is the lead sponsor of 59 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria:
Non-inclusion criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Childbearing potential
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Each subject uses the test interdental brush on one side of the mouth for 4 weeks.
Other: Test interdental brush
Each subject uses the comparative interdental brush on the contralateral side of the mouth for 4 weeks.
Other: Comparative interdental brush
Interdental brush to be used twice a day during the whole study.
Interdental brush to be used twice a day during the whole study.
Effect on dental plaque
Dental plaque (%) will be assessed according to the O'Leary method on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Effect on gingival bleeding
Gingival bleeding (%) will be assessed on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Effect on pocket depth
Pocket depth (mm) will be assessed on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Interdental hygiene assessment by subject
Interdental hygiene on each side of the mouth at Visit 2 compared to Visit 1 will be assessed by the subject using a 4-point scale (0: no change, -1: slightly improvement, 2: improvement, 3: significant improvement)
Time frame: Visit 2 (Day 29).
Adverse events recording
Adverse events occurrence will be determined by the subject spontaneous reporting, the investigator's non-leading questioning and his/her clinical evaluation
Time frame: From Visit 1 (Day 1) to Visit 2 (Day 29)
Acceptability Questionnaire assessment
Acceptability questionnaire regarding the use of the interdental brushes will be completed by the subject.
Time frame: Visit 2 (Day 29)
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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