An interventional study of Test interdental brush and Comparative interdental brush in Periodontal Disease, sponsored by Pierre Fabre Dermo Cosmetique. Recruiting at 1 site in Belgium. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-05-08.
Sponsored by Pierre Fabre Dermo Cosmetique · Not applicable, Interventional, and Prevention
The aim of this exploratory study is to evaluate the efficacy of the tested interdental brush versus comparative interdental brushes in adults with periodontal disease, over a 4-week period.
This study will take place at a single center as an intra-individual, split mouth, randomized, comparative study to evaluate the efficacy of the tested interdental brushes versus the comparative interdental brushes in adults with periodontal disease, over a 4-week period.
3 visits are planned:
Inclusion Criteria:
Non-inclusion criteria:
Each subject uses the test interdental brush on one side of the mouth for 4 weeks.
Other: Test interdental brush
Each subject uses the comparative interdental brush on the contralateral side of the mouth for 4 weeks.
Other: Comparative interdental brush
Interdental brush to be used twice a day during the whole study.
Interdental brush to be used twice a day during the whole study.
Effect on dental plaque
Dental plaque (%) will be assessed according to the O'Leary method on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Effect on gingival bleeding
Gingival bleeding (%) will be assessed on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Effect on pocket depth
Pocket depth (mm) will be assessed on each side of the mouth.
Time frame: Change from Visit 1 (Day 1) to Visit 2 (Day 29).
Interdental hygiene assessment by subject
Interdental hygiene on each side of the mouth at Visit 2 compared to Visit 1 will be assessed by the subject using a 4-point scale (0: no change, -1: slightly improvement, 2: improvement, 3: significant improvement)
Time frame: Visit 2 (Day 29).
Adverse events recording
Adverse events occurrence will be determined by the subject spontaneous reporting, the investigator's non-leading questioning and his/her clinical evaluation
Time frame: From Visit 1 (Day 1) to Visit 2 (Day 29)
Acceptability Questionnaire assessment
Acceptability questionnaire regarding the use of the interdental brushes will be completed by the subject.
Time frame: Visit 2 (Day 29)
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Pierre Fabre Dermo Cosmetique