An interventional study of telerehabilitation in Bronchiectasis and Telerehabilitation, sponsored by Hospitales Universitarios Virgen del Rocío. Not yet recruiting at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-20.
Sponsored by Hospitales Universitarios Virgen del Rocío · Not applicable, Interventional, and Treatment
Background: Home-based telerehabilitation (TR) has demonstrated benefits comparable to conventional rehabilitation in patients with chronic obstructive pulmonary disease, asthma, and pulmonary fibrosis. However, TR has not been thoroughly investigated in patients with bronchiectasis, despite evidence suggesting improvements in exercise capacity and quality of life.
Aims: To evaluate the effects of TR on functional capacity, quality of life, and inflammatory biomarkers, as well as its safety in patients with bronchiectasis.
Study design: Single-center randomized controlled trial with a parallel-group design.
Methods: Patients diagnosed with bronchiectasis will be recruited from the Surgical Medical Unit for Respiratory Diseases at Virgen del Rocío University Hospital. Participants will be randomly assigned to one of two groups: a control group receiving usual care, and a TR group undergoing supervised physical training for 12 weeks, three times per week. Outcome measures will include the 6-minute walk test, quality-of-life questionnaires, pulmonary function tests, symptom assessment, and adverse event recording, as well as sputum microbiology and analysis of inflammatory biomarkers. Assessments will be conducted at baseline and at the end of the intervention.
Expected results: A 12-week TR program is expected to significantly improve exercise capacity and quality of life in the intervention group. Additionally, this study may contribute to the development of future clinical guidelines regarding the use of TR in patients with bronchiectasis.
404 studies on the registry are indexed under Bronchiectasis; 125 are open to participants now.
This study's planned enrollment of 80 is above the median of 60 across 263 interventional studies indexed under Bronchiectasis.
Browse Bronchiectasis studies →Hospitales Universitarios Virgen del Rocío is the lead sponsor of 33 studies on the registry; 8 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Standard care for exacerbation and follow-up without rehabilitation.
Telerehabilitation: 12 weeks of supervised exercise interventions.
Other: telerehabilitation
3 days per week: supervised resistance training that includes upper and lower limb and core exercises, initially using with low weights, performed in 2 sets with 10 repetitions, with progressive weekly increases depending on symptoms. 4 days per week: endurance training. Patients will walk on days when they do not perform strength training, for at least 30 minutes, with the duration gradually increased each month depending on their symptoms.
Also known as: physical activity
6-minute walk distance
Patients walk through a 30-meter corridor faster than they can for 6 minutes
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
The quality of life
ST Georges respiratory questionnaire COPD assessment test. Scores range from 0 to 100, where 0 represents the best possible health (no limitations) and 100 the worst health status.
Time frame: Baseline, after 12 weeks of telerehabilitation program and at 3 and 6 months after completing the telerehabilitation program.
Pulmonary function tests
pulmonary function tests (FEV1, FVC)
Time frame: Baseline and after 12 weeks of telerehabilitation program.
Respiratory Muscle Strength
Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).
Time frame: Baseline and after 12 weeks of telerehabilitation program.
Exahled Nitric Oxide Fraction (FeNO)
Exahled Nitric Oxide Fraction (FeNO)
Time frame: Baseline and after 12 weeks of telerehabilitation program.
Sputum microbiology
The presence of Pseudomonas Aeruginosa through microbiological analysis of sputum
Time frame: Baseline, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Biological markers of Biological markers of inflammation
PCR, neutrophil/lymphocyte ratio, IL-1β, IL-6, TNF-α levels.
Time frame: Baseline and after 12 weeks of telerehabilitation program.
Dyspnoea
Modified Medical Research Council (mMRC) dyspnoea scale. Minimum value (Grade 0): Absence of dyspnea. Maximum value (Grade 4): Severe dyspnea.
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Bronchiectasis severity
The E-FACED questionnaire. Scores range from 0 to 9, where a score of 0-3 indicates mild severity, 4-6 indicates moderate severity, and ≥ 7 indicates severe disease.
Time frame: Baseline and after 12 weeks of telerehabilitation program.
Change from baseline in respiratory symptoms and adverse events.
Change from baseline in respiratory symptoms and adverse events.
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Blood pressure
Measurement of blood pressure using a sphygmomanometer. Blood Pressure Ranges in Adults: Normal: Less than 120/80 mmHg. Elevated: 120-129 / \< 80 mmHg. Hypertension Grade 1: 130-139 / 80-89 mmHg. Hypertension Grade 2: ≥ 140 / ≥ 90 mmHg.
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Heart rate
The heart rate value recorded by the sphygmomanometer will be documented.
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Oxygen saturation (SpO2)
Oxygen saturation is measured using a pulse oximeter. Values between 95% and 100% are considered normal. Values below 90% are considered hypoxemia. Normal values range between 95% and 100%.
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Exacerbation
Exacerbation rate
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Telerehabilitation adherence
Number of sessions completed by participants who take part in the rehabilitation program and training parameters registration
Time frame: Baseline, week 6, after 12 weeks of telerehabilitation program, and at 3 and 6 months after completing the telerehabilitation program.
Plan to share: No
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Hospitales Universitarios Virgen del Rocío