An interventional study of Hemostatic sponge post tooth extraction in Hemostasis, Wound Closure and Pain, sponsored by Universidad Nacional de Caaguazu. Completed at 1 site in Paraguay. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-04-14.
Sponsored by Universidad Nacional de Caaguazu · Not applicable, Interventional, and Treatment
Tooth extraction is a common dental procedure, where hemostasis is crucial for patient recovery. This study evaluates the effectiveness of hemostatic sponges in controlling bleeding and promoting postoperative healing.
A non-randomized experimental study was conducted at the Santo Tomás de Aquino School of Dentistry Clinic with 30 patients undergoing tooth extractions. They were divided into two groups: one with hemostatic sponges (experimental) and the other without (control). Variables such as bleeding time, wound depth, pain, and postoperative complications at 1, 8, and 15 days were analyzed.
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's enrollment of 30 is below the median of 66 across 8,493 interventional studies indexed under Pain.
Browse Pain studies →Universidad Nacional de Caaguazu is the lead sponsor of 5 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
The colocation of a hemostatic sponge post extraction in the wound
Procedure: Hemostatic sponge post tooth extraction
No colocation of hemostatic sponge in the wound
Effectiveness of hemostatic sponges in patients undergoing tooth extractions, analyzing immediate hemostasis and scar development at different postoperative times.
Post-tooth extraction hemostasis.
Time measured in minutes from the end of the extraction procedure until complete bleeding cessation, assessed by direct clinical observation.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Wound dimensional changes
Measurement of socket length, width, and depth using calibrated periodontal probe. Data will be reported as mean change in millimeters from baseline measurement.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Pain intensity
Pain intensity measured using Visual Analog Scale (VAS). Higher scores indicate worse outcome.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Edema assessment
Edema assessed by clinical examination using a 4-point scale: 0 = no edema, 1 = mild edema, 2 = moderate edema, 3 = severe edema. Higher scores indicate worse outcome.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Tissue color changes evaluation
Evaluation of tissue color changes using a standardized 5-point wound healing color scale: 1 = normal pink, 2 = pale pink, 3 = red, 4 = dark red/purple, 5 = black/necrotic. Higher scores indicate worse healing.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Post-extraction complications
Incidence of post-extraction complications including but not limited to: dry socket, infection, delayed healing, excessive bleeding, and nerve damage. Complications will be assessed by clinical examination and participant reporting.
Time frame: From the beggining of the treatment inmediatly, then at day 1, day 8, and at day 15
Plan to share: Yes — On request
Supporting information: Study protocol, Informed consent form
Time frame: On request
Access criteria: Other researchers
Ran from Aug 2024 to primary completion in Mar 2025, 7 months.
Of 3,731 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's 7 months is below that.
Counting every sponsor, half of 3,830 studies reached it within 10 months; a quarter within 4 and three quarters within 23.
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This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Universidad Nacional de Caaguazu