An interventional study of DBT group psychotherapy and Supportive Psychotherapy in Borderline Personality Disorder (BPD), sponsored by Natalia Dewi Wardani, MD. Completed at 1 site in Indonesia. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-03-06.
Sponsored by Natalia Dewi Wardani, MD · Not applicable, Interventional, and Treatment
In the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients with Borderline Personality Disorder: A Study of Therapeutic Alliance, Depression, Cognitive Function, Impulsivity, Suicide Risk, BDNF Levels, NFkB Levels, SOD Levels."
Psychotherapy for Borderline Personality Disorder provided weekly for 13 weeks. Patients have given a logbooks. Researchers monitored patients weekly by telephone and monitor them during outpatient visits in the second, fourth, sixth, eighth, and twelfth weeks. Blood samples were taken before and 13 weeks after treatment. During the study, patients were advised not to consume any medications or herbal remedies outside of those prescribed by the doctor and recorded in the study.
278 studies on the registry are indexed under Borderline Personality Disorder; 70 are open to participants now.
This study's enrollment of 66 is close to the median of 70 across 221 interventional studies indexed under Borderline Personality Disorder.
Browse Borderline Personality Disorder studies →Natalia Dewi Wardani, MD is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
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DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
13 weeks, one session per week. Each week, 2-hour dialectical therapy group session for 5 patients per group.
Behavioral: DBT group psychotherapy
13 weeks, one session per week. Each week, one 30-minute session of individual supportive psychotherapy.
Behavioral: Supportive Psychotherapy
13 weeks, one session per week. Each week, one 2-hour dialectical therapy group session for 5 patients in a group.
13 weeks, one session per week. Each week, one 30-minute session of individual supportive psychotherapy
Therapeutic Alliances with California Psychotherapy Alliance Scales (CALPAS)
California Psychotherapy Alliance Scales (CALPAS) score. A higher CALPAS (California Psychotherapy Alliance Scale) score indicates a stronger, more positive therapeutic alliance between a patient and their therapist. The California Psychotherapy Alliance Scale (CALPAS) uses a 7-point Likert scale for its 24 items, ranging from 1 ("not at all") to 7 ("very much so"). Minimum score 24 and maximum score 168.
Time frame: 13 weeks
Depression with GRID Hamilton Depression Rating Scale (GRID HAM-D)
GRID Hamilton Depression Rating Scale (GRID HAM-D) score, interval, higher total scores indicating greater severity of depression. Minimum Score: 0 (No depression) Maximum Score: 52 (Severe depression)
Time frame: 13 weeks
cognitive function with Montreal Cognitive Assesment versi Indonesia (MoCA-Ina)
Montreal Cognitive Assesment Indonesian version (MoCA-Ina) score, interval. A 30-point screening tool validated to detect mild cognitive impairment (MCI) and dementia in Indonesia, with a score of 26 or higher considered normal.
Time frame: 13 weeks
impulsivity with Barrat Impulsiveness Scale (BIS11)
Barrat Impulsiveness Scale (BIS11) score, interval, Higher scores indicate greater impulsivity, with 30-51 indicating low, 52-71 average, and 72+ high impulsivity.
Time frame: 13 weeks
Suicide Risk with Columbia Suicide Severity Rating Scale (CSSRS)
Columbia Suicide Severity Rating Scale (CSSRS) score, interval, Any "Yes" answer to behavior or ideation requires further clinical assessment.
Time frame: 13 weeks
NFkB Levels in ng/ml
ratio scale, nanogram/mililiter
Time frame: 13 weeks
BDNF level in pg/ml
BDNF level in picogram/mililiter, ratio scale
Time frame: 13 weeks
SOD levels in ng/ml
ratio scale, nanogram/mililiter
Time frame: 13 weeks
Plan to share: No — The data are not publicly available due to privacy or ethical restrictions. The dataset involves sensitive information from minors regarding mental health, and sharing it publicly would compromise participant confidentiality as per the ethical approval obtained.
This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Borderline Personality Disorder →
Natalia Dewi Wardani, MD