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CompletedNCT07429175Updated Feb 24, 2026

Sensory-Motor Relationship in Unilateral CP

An observational study in Cerebral Palsy, Hemiplegic, sponsored by Ankara University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 6 Years to 15 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-24.

Sponsored by Ankara University · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
110
Ages
6 Years to 15 Years
Sex
All
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Study summary

Cerebral palsy (CP) is characterized by many problems related to brain damage. One of these is sensory impairment. Sensory impairments in CP patients can also occur together with motor functions. Detecting sensory impairments (two-point discrimination, vibration, joint position sense, thermal sensation, stereognosis, graphesthesia) in the arm, forearm, and hand (upper extremity) in CP patients and investigating their relationship with motor functions is important. The aim of this research is to investigate the relationship between upper extremity sensory impairments and motor functions in patients diagnosed with unilateral (affecting one half of the body) CP.

Read the detailed description

The aim of this study is to investigate the relationship between sensory impairments and upper extremity motor functions in patients with unilateral cerebral palsy (CP). It will be planned as a cross-sectional study. The study will include 55 unilateral CP patients and 55 healthy volunteers. Sensory functions evaluated include two-point discrimination, joint position sense, vibration sense, thermal sense, stereognosis, and graphesthesia. Motor functions will be assessed using the Gross Motor Functional Classification System (GMFSS), Hand Skills Classification System (ESCS), Abilhand-Kids scale, Box and Block test, and Nine Hole Peg test. The relationship between sensory parameters and motor functions will be investigated.

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Conditions studied

  • Cerebral Palsy, Hemiplegic

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Keywords

  • cerebral palsy
  • sensory function
  • motor function
03

In context

Cerebral Palsy

1,853 studies on the registry are indexed under Cerebral Palsy; 435 are open to participants now.

This study's enrollment of 110 is above the median of 63 across 455 observational studies indexed under Cerebral Palsy.

Browse Cerebral Palsy studies →

Lead sponsor

Ankara University is the lead sponsor of 312 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
6 Years to 15 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Children with unilateral cerebral palsy (CP) who meet the inclusion criteria and who apply to the Physical Medicine and Rehabilitation Department Clinic or Outpatient Clinic of Ankara University Faculty of Medicine, as well as healthy volunteers, will be included in the study.

Inclusion criteria

  • Children aged 15 with unilateral cerebral palsy (CP)
  • Being between Gross Motor Functional Classification System I-IV
  • Not having undergone surgery or botulinum toxin application to the affected upper extremity in the last 6 months
  • Understanding what is said and being able to follow commands
  • The patient or their relatives having completed an informed consent form

Exclusion criteria

Exclusion Criteria:

  • Having a neurological disease affecting the motor and sensory system other than cerebral palsy
  • The participant having a dermatological, vascular, or orthopedic problem in the upper extremity that would prevent assessment
  • Having uncorrected vision and hearing problems
  • Having autism spectrum disorder and attention deficit hyperactivity disorder
  • Having insufficient intelligence level
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
110 participants (actual)
Patient registry
No

Groups and cohorts

  • Patient Group

    Children aged 6-15 with unilateral (hemiplegic) cerebral palsy

  • Healthy Group

    Healthy children aged 6-15

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What researchers measure

Primary outcomes

  1. Sensory Function:Two-point discrimination

    Two-point discrimination is defined as the ability to distinguish between two simultaneous points of touch, which is most acute in areas of the skin with a high density of touch receptors, such as the fingers and face. The test will be performed using a discriminator device called an esthesiometer.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  2. Sensory Function:Joint position sense

    Joint position sense is the ability to detect body segment position in space and is commonly used to represent proprioceptive performance.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  3. Sensory Function:Vibration

    Assessment of vibration sense is the best clinical test of the dorsal column pathway. A low-frequency (128 Hz) tuning fork is applied to bony prominences and the patient (with closed eyes) is asked to report when the vibration starts and stops.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  4. Sensory Function:thermal sense

    The volunteer's upper extremity is successively touched with tubes filled with hot and cold water, and the volunteer is asked to respond as hot or cold. Thermal sensation is recorded as 'preserved', 'impaired', or 'unable to assess'.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  5. Sensory Function:Stereognosis

    Without visual or auditory cues, objects are placed in a sequence, and the child is asked to grasp them and identify the name of the object. Each object is awarded '1' point for being correctly identified, and '0' points for not identifying it. Scores ranging from 0 to 6 are recorded.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  6. Sensory Function:Graphesthesia

    Six different drawings-letters, numbers, circles, and vertical lines-are made on the palm of the volunteer's hand using a blunt pencil, without any visual or auditory stimuli. Each correct drawing earns '1' point, and each incorrect drawing earns '0' points. Scores ranging from 0 to 6 are recorded.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  7. Motor Function: Gross Motor Functional Classification System

    This classification system consists of 5 levels.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  8. Motor Function: Hand Skills Classification System

    This classification system consists of 5 levels.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  9. Motor Function: Abilhand-Kids Scale

    Twenty-one daily activities were evaluated. Participants were asked to rate an activity-which the child attempted to perform independently using both upper extremities-on a scale of 0-42 points.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  10. Motor Function: Nine Hole Peg Test

    The Nine Hole Peg Test was developed to measure finger dexterity, also known as fine manual dexterity. The test consists of a wooden board with nine holes and nine small sticks designed to be inserted into those holes. The participant is asked to take the sticks from the box one by one with the hand being tested and insert them into the holes as quickly as possible; then, they must remove the sticks one by one and return them to the box.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

  11. Motor Function: Box and Block Test

    The Box and Block Test (BBT) measures unilateral gross manual dexterity. Participants are given 60 seconds to move wooden blocks by hand to the opposite compartment as quickly as possible. At the end of 60 seconds, the number of wooden blocks transferred to the opposite compartment is noted.

    Time frame: Single assessment at baseline (cross-sectional evaluation)

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Study locations

1 site
  • Ankara University, Faculty of Medicine
    Ankara, Turkey (Türkiye)
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07429175
Lead sponsor
Ankara University
Responsible party
Birkan Sonel Tur (Professor, MD, Ankara University) — Principal investigator
First posted
Feb 24, 2026
Start date
Sep 1, 2024
Primary completion
Nov 30, 2025
Completion
Nov 30, 2025
Last update
Feb 24, 2026

Study contacts

Birkan Sonel Tur, Professor
principal investigator · Ankara University, Faculty of Medicine

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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