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RecruitingNCT07428694Updated Feb 24, 2026

From Bench to Bedside: A Machine Learning Tool for the Detection of Inspiratory Leak

An observational study in Chronic Respiratory Failure, sponsored by University of Oslo. Recruiting at 1 site in Norway. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-24.

Sponsored by University of Oslo · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

Study of the applicability of machine learning tools in detecting inspiratory leakage in longterm non-invasive ventilation. The study was conducted in two stages. Firstly the ML model was trained on both bench model created scenarios and then ten patients. And secondly the success of the model was assessed in a proof of concept pilot study of ten patients.

02

Conditions studied

  • Chronic Respiratory Failure
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients undergoing treatment with Lumis 100/150 for type 2 chronic resiratory failure

Inclusion criteria

  • elective hospitalisation for control of non-invasive ventilation
  • use of ResMedLumis 100/150 ventilator
  • treatment for >3 months

Exclusion criteria

Exclusion Criteria:

  • current exacerbation
04

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
20 participants (estimated)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Correct interpretation of inspiratory leak by machine learning tool

    Measured in comparison with god standard method of polygraphy

    Time frame: one year

06

Study locations

1 of 1 sites recruiting
  • Oslo University Hospital
    Oslo, Norway
    Recruiting
07

Registry details

Key details

Study ID
NCT07428694
Lead sponsor
University of Oslo
Collaborators
Oslo University Hospital
Responsible party
Marte Skogstad Allgot (Principal investigator, University of Oslo) — Principal investigator
First posted
Feb 24, 2026
Start date
Oct 1, 2025
Primary completion
Oct 1, 2026 (estimated)
Completion
Oct 1, 2026 (estimated)
Last update
Feb 24, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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