An interventional study of Implantoplasty and Open flap debridement alone in Peri-Implantitis and Peri-implant Mucositis, sponsored by University of Oslo. Recruiting at 2 sites in Norway. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-29.
Sponsored by University of Oslo · Not applicable, Interventional, and Treatment
This double arm, split-mouth, single centre, controlled, randomised clinical study is designed to examine the effect of implantoplasty in treatment of peri-implantitis.
Peri-implantitis will be treated with open flap debridement, with or without implantoplasty.
322 studies on the registry are indexed under Peri-Implantitis; 88 are open to participants now.
This study's planned enrollment of 35 is below the median of 40 across 195 interventional studies indexed under Peri-Implantitis.
Browse Peri-Implantitis studies →University of Oslo is the lead sponsor of 177 studies on the registry; 24 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Open flap debridement with implantoplasty treatment
Procedure: Implantoplasty · Procedure: Open flap debridement alone
Open flap debridement withput implantoplasty treatment
Procedure: Implantoplasty · Procedure: Open flap debridement alone
Implantoplasty is the mechanical smoothening of rough titanium implants as part of the surgical treatment of peri-implantitis. Treatment is thought to facilitate self-performed oral hygiene.
Open flap debridement alone
Bleeding on probing
Measured with a periodontal probe
Time frame: 12 months after treatment
Bleeding on probing
Measured with a periodontal probe
Time frame: 24 months after treatment
Suppuration
Visible suppuration upon probing the implant with a periodontal probe
Time frame: 12 months after treatment
Suppuration
Visible suppuration upon probing the implant with a periodontal probe
Time frame: 24 months after treatment
Pocket probing depth
Measured with a periodontal probe
Time frame: 12 months after treatment
Pocket probing depth
Measured with a periodontal probe
Time frame: 24 months after treatment
Changes in patient-reported quality of life (QoL)
To assess QoL changes related to mouth and teeth prior to therapy to after therapy by the use of "The Oral Impacts on Daily Performance (OIDP)" instrument. Each question is assessed by a 5-point scale; (1) never affected; (2) less than once a month; (3) once or twice a month; (4) once or twice a week; and (5) every or nearly every day. The higher number represents more severe impact on quality of life; e.g. worse outcome. Each item will be dichotomised yielding the categories (A) affected; including scale categories (2)-(5), and (B) unaffected; including category (1)
Time frame: Preoperatively compared to 24 months after treatment
Clinical attachment loss measurements
Measured with a periodontal probe
Time frame: 12 months after treatment
Clinical attachment loss measurements
Measured with a periodontal probe
Time frame: 24 months after treatment
Radiographic bone loss
Measured on standardized radiograps
Time frame: 12 months after treatment
Radiographic bone loss
Measured on standardized radiograps
Time frame: 24 months after treatment
Implant fracture
Clinical examination to assess whether implants have fractured following treatment
Time frame: 24 months
Started Oct 2019 (actual). Primary completion is estimated for Jun 2027, 92 months after the start.
Of 119 non-industry interventional studies with no phase under Peri-Implantitis, half reached primary completion within 26 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 46. This study's planned 92 months is above that.
Counting every sponsor, half of 126 studies reached it within 26 months; a quarter within 12 and three quarters within 40.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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