ClinicalTrials.gg
Not yet recruitingNCT07406425COCO-CAREUpdated Sep 24, 2026

Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People.

An interventional study of Coconut oil mouth care and Glycerin mouthwashes in Geriatrics and Oral Health Care, sponsored by University Hospital, Limoges. Not yet recruiting at 2 sites in France. Open to participants aged 75 Years and older. Per ClinicalTrials.gov, last updated 2026-09-24.

Sponsored by University Hospital, Limoges · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
94
Allocation
Randomized
Ages
75 Years and older
Sex
All
01

Study summary

This is a prospective, longitudinal, randomised, open-label, multicentric, interventional, comparative superiority study.

The main objective is to demonstrate the superiority of oral care with coconut oil on the oral status of elderly people hospitalised in geriatrics, versus oral care with glycerol sticks.

02

Conditions studied

  • Geriatrics
  • Oral Health Care

Keywords

  • geriatrics
  • oral health care
  • elderly
  • coconut oil
  • palliative care
03

In context

Lead sponsor

University Hospital, Limoges is the lead sponsor of 264 studies on the registry; 38 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
75 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged 75 and over
  • Patients hospitalised in geriatric medicine and geriatric SMR departments
  • Patients able to open their mouths for treatment
  • Patients not able to carry out their oral hygiene on their own
  • Patients who have given their written consent (consent of the patient or patient consent accompanied by the designated representative if the patient is unable to give written consent)

Exclusion criteria

Exclusion Criteria:

  • Patients with a known allergy to coconut
  • Patients requiring medicated mouth care as prescribed by a doctor
  • Patients under guardianship, tutorship or curatorship
  • Confused patients who have had medically diagnosed dehydration for less than 48 hours
  • Patients with swallowing difficulties
  • Patients in the terminal phase of end of life

Secondary exclusion criteria:

  • Patients leaving the department between D1 and D8 (whatever the reason for discharge, and including in the event of death)
  • Patients whose condition progresses towards a terminal phase of the end of life between D1 and D8
  • Patients experiencing an allergic reaction to Coconut Oil during the study
  • Patients who may present with dehydration during the study
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
94 participants (estimated)

Study arms

  • Experimental
    Coconut oil mouth care

    Daily oral care is done with coconut oil throughout the patient's hospitalization

    Procedure: Coconut oil mouth care

  • Active comparator
    Glycerin mouthwashes

    Daily oral care is performed with glycerin sticks as in current practice.

    Procedure: Glycerin mouthwashes

Interventions

  • ProcedureCoconut oil mouth care

    Daily oral care is done with coconut oil throughout the patient's hospitalization

  • ProcedureGlycerin mouthwashes

    Daily oral care is performed with glycerin sticks as in current practice.

06

What researchers measure

Primary outcomes

  1. Revised Oral Assement Guide (ROAG) between Day 1 and Day 8

    Change in total score between Day 1 (D1) and Day 8 (D8) on the Revised Oral Assessment Guide (ROAG), translated in French. The scale assesses 8 indicators (voice, swallowing, lips, tongue,saliva, mucous membranes, gums and teeth) according to 3 levels. The result gives a total score out of 24 points

    Time frame: From Day 1 to Day 8

Secondary outcomes

  1. Weekly ROAG scores (Revised Oral Assment Guide)

    Weekly ROAG scores (overall score and score per indicator) for all participants included until discharge (an assessment will also be carried out at discharge).

    Time frame: Every week from the date of inclusion until the date of discharge, on average over 37 days.

  2. ROAG betwen Day 1 (D1) and Day 8 (D8) for patients with "palliative care" status

    Changes in the ROAG overall score between D1 and D8, translated in French. The degree of dependence is assessed using the KATZ scale (dependence group) at inclusion.

    Time frame: from Day 1 to Day 8

  3. Number of oral care stopped

    Number of patients who stopped the oral care initially proposed and reasons for discontinuing oral care, evaluated at the end of the study

    Time frame: At the end of the study, on average of 37 days.

07

Study locations

2 sites
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2026; primary completion for Apr 2028, 18 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 20, 2026
First posted
Feb 12, 2026
StartEst.
Oct 1, 2026
Primary completionEst.
Apr 15, 2028
CompletionEst.
Jun 1, 2028
Last update
Sep 24, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07406425
Responsible party
Sponsor
First posted
Feb 12, 2026
Start date
Oct 1, 2026 (estimated)
Primary completion
Apr 15, 2028 (estimated)
Completion
Jun 1, 2028 (estimated)
Last update
Sep 24, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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